JPS63256859A - Automatic analysis instrument - Google Patents

Abstract

PURPOSE:To quickly provide a result of inspection for which urgency is high by outputting the result of an electrolyte item in preference to a colorimetry item when only the electrolyte item is requested as the measurement item of a specimen. CONSTITUTION:The colorimetry item and the electrolyte item are different in analysis method and, therefore, the colorimetry item necessitates about 10min and the electrolyte item about 1min before the result of the analysis is decided. Two tables; a table for priority output which stores only the result of the electrolyte item among the measurement items and a table for general output which stores the results of computation of the other items except said item, are thereupon provided. Decision 101 as to whether the request is only for the electrolyte item is made when the measurement item is the request for only the electrolyte item. Storage 102 to the table for priority output is executed in the case of YES. Output is delivered from this priority table first at the time of outputting. The result of the inspection for which the urgency is high is, therefore, quickly provided.

Description

DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to an automatic analyzer, and particularly to an automatic analyzer suitable for measuring colorimetric items and electrolyte items that require different measurement times.

[Conventional technology]

With the development of clinical biochemical tests, it has become desirable to be able to measure colorimetric items and electrolyte items simultaneously. Conventionally,
The method used was to output one sample at a time in the order in which it was sampled. That is, the measurement results of the specimen are always output at regular intervals in accordance with the output timing of colorimetric items that require a long measurement time.

[Problem that the invention seeks to solve]

The above-mentioned conventional technology outputs the measurement results at the output timing of the colorimetric measurement results, regardless of whether or not there is a request for measurement of colorimetric items. For this reason, electricity.

When only the electrolyte item was requested, the output of the electrolyte item took the same amount of time as the colorimetric item, even though the measurement time was shorter than the colorimetric item.

Electrolyte items are very urgent test items, as they are sometimes measured on seriously ill patients who have fallen into a coma, and it is necessary to output measurement results quickly. For this reason,
There was a problem in that highly urgent test results could not be provided to users quickly.

SUMMARY OF THE INVENTION An object of the present invention is to solve these conventional problems and provide an automatic analyzer that can quickly output measurement results at a timing that meets the needs of the user.

[Means for solving problems]

The purpose of the above is to provide two tables: a priority output table that stores calculation results for only electrolyte items as measurement request items, and a general output table that stores calculation results for other items. This is achieved by providing a function to manage the output timing of the calculation results stored in the table.

[Effect]

Calculation results for electrolyte items that must be output quickly,
By storing the data in the priority output table and performing the data in the priority table first when outputting, electrolyte items can be output quickly regardless of the measurement time of colorimetric items.

〔Example〕

Hereinafter, one embodiment of the present invention will be described in detail with reference to the drawings.

FIG. 1 shows the configuration of an embodiment of the present invention.

The reaction table 1 has a plurality of reaction vessels 2 serving as measurement cells on its circumference, and can freely rotate around a rotation axis 3. The sample table 4 has a plurality of sample containers 5 on its circumference and can freely rotate around a rotation axis 6. The sample suction and discharge tube 7 is connected to a dispensing mechanism 59, and the sample can be sucked and discharged by the suction and discharge operation of the dispensing mechanism 59. This operation is performed in the order of colorimetry and electrolyte. Further, the sample intake/discharge pipe 7 is connected to the reaction table 1, the sample table 4, and the electrolyte measuring device 6 around the rotating shaft 8 by the rotating operation of the dispensing mechanism 59.
A sample suction/discharge tube cleaning mechanism 9 is installed under the rotating passage path of the sample suction/discharge tube 7.

The reagent is dispensed using the reagent dispenser 10. Channel 11. Channel 12.
Channel 13. This is performed by a reagent dispensing mechanism consisting of a flow path switch 14 and a reagent dispenser 15.

The stirring rod 2o is connected to the stirring mechanism 21, and the stirring rod 2o is connected to the stirring mechanism 21.
It rotates by the rotational movement of , and goes up and down by the vertical movement. A spectrometer 30 faces a light source lamp 31 and a reaction table 1.
When rotated, the reaction vessel 2 passes through the light beam 32, and the light absorption measurement is performed at that time.

Details of the electrolyte measuring bag @60 are as shown in FIG. First, the internal standard solution syringe 64 starts operating and discharges the internal standard solution 65 into the dilution tank 68 . Next, the zipper
The syringe 69 operates to draw the internal standard solution in the dilution tank 68 into the electrolyte constant temperature tank 70 . The internal standard solution is stopped within the ion selection electrode 61°62.63, and the electromotive force of the internal standard solution is measured. This measurement result is stored in the storage device 5o in FIG.
is memorized.

The principles of analysis of colorimetric items will be described below with reference to FIG. When the sample container 5 containing the sample to be measured, for example, serum, comes to the sampling position 41, the tip of the sample suction/discharge tube 7 is immersed into the sample container 5, sucks in a certain amount of serum, and then the sample suction/discharge tube 7
hold within. After that, the sample suction and exhaust pipe 7 is connected to the reaction table 1.
The blood serum held in the reaction container 2, which has been transferred to the discharge position 51, is discharged.

After the discharge is completed, the reagent suction/discharge tube is moved onto the reagent suction/discharge tube cleaning mechanism 9 and the inside and outside of the sample suction/discharge tube 7 is washed with water. When the sampling operation is completed, the reaction container 2 reaches the sample dispensing position 52 through a transfer process. Therefore, the flow path changer 14
1 and the flow path 12, the sample dispenser 15 discharges the reagent in the sample container 16 from the reagent discharge tube 10 into the reaction container 2.

By the above operation, the sample to be measured mixes with the reagent and starts a reaction. Thereafter, the reaction container 2 that has reached the stirring position 53 through the transfer process again is stirred by the stirring frame 20 to continue the reaction. Thereafter, the reaction container 2 reaches the cleaning position 54 through a further transfer process. During this time, that is, during the transfer process from the reagent discharge position 52 to the washing position 54,
A light absorption measurement is carried out in the spectrometer 30 each time the reaction vessel 2 passes through the light beam 32 .

The reaction vessel 2 that has reached the cleaning position 54 has its internal liquid sucked and discharged by the reaction vessel suction and discharge pipe 42, is washed by the cleaning mechanism 58 through cleaning positions 55, 56, and 57, and is then transferred again from the discharge position 51 through the subsequent transfer process. Used as reaction vessel 2.

Next, the principle of measuring electrolyte items will be explained with reference to FIGS. 1 and 2. The sample 22 set on the sample table 4 is moved to the center of the dilution tank 68 by the sample suction/discharge pipe 7, and the sample 22 is discharged into the dilution tank 68.

At this time, the diluent syringe 66 is activated and the diluent 6
7 is discharged into the dilution tank 68. The sample 22 mixed with the diluent 67 is sucked into an electrolyte constant temperature bath 70 by a zipper syringe 69, and the electromotive force of the electrolyte is measured. and,
It is stored in the storage device 50. Furthermore, the concentration of the electrolyte is calculated from the difference between the electromotive force of the internal standard solution 65 stored in the storage device 50. The mixed liquid of the measured sample and diluent is transferred to the waste liquid tank 71 using a zipper syringe 69.
is discharged. All these operations are controlled by the control device 40.

As mentioned above, because the analytical methods for colorimetric items and electrolyte items are different, there is a difference in the time from the start of the analysis until the analysis results are finalized, with the colorimetric item being approximately 10 minutes and the electrolyte item being approximately 10 minutes. It is 1 minute. For this reason, in the past, even though the electrolyte items were determined first, they were not output until the colorimetric items were determined.

The difference in output timing between the conventional method and the present invention will be explained with reference to FIG. When the analysis starts, N1 ・
Sampling is performed in the order of El, N2, and N3.

For general sample N3 and emergency sample E1, for which only electrolyte items were requested to be measured, the data is finalized one minute after the end of sampling, but in the past, output to the outside was performed 10 minutes after the end of sampling.

In contrast, in the present invention, output to the outside is performed immediately after electrolyte data is determined.

In addition, in claim 2, only in the case of an emergency sample for which measurement of only electrolyte items is requested, the electrolyte data is output to the outside immediately after it is determined, and when only the electrolyte items are requested for a general sample, the conventional method is output. will be output at the same timing.

Next, the output process to the printer when a request is made to measure only electrolyte items as measurement items for general or emergency samples will be explained with reference to the flowcharts of FIGS. 4 and 6.

FIG. 4 shows a process for storing calculation results in an output table. First, it is determined 101 whether there is only an electrolyte item, and if there is only an electrolyte item, the calculation result is stored 102 in a priority output table. Furthermore, if the analysis item is only colorimetry or colorimetry and electrolyte, the calculation results are stored 103 in the general output table.

FIG. 6 shows the process of outputting the data stored in the output table to the printer. First, a determination 110 is made as to whether it is the timing to output, and if it is the timing to output, the priority output table is Reference 111 is performed. Next, it is determined 112 whether priority output data is stored.
and if it is stored, output to the printer 11
3, clearing 114 of priority output data is executed.

On the other hand, if there is no priority output data, it is determined 119 whether the data pointed to by the pointer (information indicating the output order of data in the output table) has been output, and if it has been output, the pointer is updated 120.

If the data pointed to by the pointer has not been output yet, reference 115 is made to the general output table. Next, a determination 116 is made as to whether data is stored, and if data is present, output 117 to the printer is performed. Then, the pointer is updated 118.

The above has described the output to the printer when the measurement request item is only an electrolyte item, but this method is suitable for an emergency device that needs to output the electrolyte item particularly quickly.

Next, we will explain how to output to the printer when a request is made to measure only electrolyte items for an emergency sample (a sample to be analyzed during a general analysis). This method is suitable for routine testing equipment.

FIG. 5 shows the process of storing the calculation results in the output table. First, it is determined 105 whether the analysis sample is an emergency sample, and if it is a general sample, the calculation result is stored 108 in a general output table. In the case of an emergency sample, it is determined whether the analysis items are only electrolyte items (10).
6 is performed, and in the case of only electrolyte items, a determination 107 is performed on the calculation results in the priority output table. If the analysis item is only colorimetry or colorimetry and electrolyte, storage 108 is performed in the general output table. In addition, the output method to the printer is the same as the output method when only electrolyte items are requested for measurement as described in the explanation of Figure 6, but urgent samples are output with priority and only electrolyte items are requested. This is the case.

〔Effect of the invention〕

According to the present invention, when colorimetric items and electrolyte items that have different measurement times are analyzed, the electrolyte items can be output preferentially, so there is an effect that highly urgent test results can be provided quickly. Furthermore, in claim 2, since electrolyte items are not output preferentially except in emergencies, it is effective in managing analysis results in routine analysis.

[Brief explanation of drawings]

FIG. 1 is a configuration diagram of an automatic analyzer that is an embodiment of the present invention,
Fig. 2 is a configuration diagram of the electrolyte measuring device, Fig. 3 is an output timing chart of the conventional and present invention, Figs. 4 and 5 are diagrams showing the process of storing calculation results in an output table, and Fig. 6 is a diagram showing the process of storing calculation results in an output table. FIG. 6 is a diagram showing a process of outputting calculation results from an output table to a printer. 2... Reaction container, 15... Sample dispenser, 21...
Stirring mechanism, 30... Spectrometer, 40... Control device, 5
0...Storage device, 58...Washing mechanism, 69...Dispensing mechanism, 64...Syringe for internal standard solution, 66...
Syringe for diluted liquid, Kaya 1 Prisoner Kaya 20 7θ 14,, J pull 41σ, 11! C;～-Condolence Shiso〉Shiro S
9 Sinopa Shirinshi 7θ Electrolyzed Sisters 71 Haiyuu Yu〉fumo 3 Mouchihaya 4 Eyes Leaf 5 Prisoners

Claims (1)

[Scope of Claims] 1. A spectrometer that optically detects the characteristics of a specimen, a storage device that stores an output signal output from the spectrometer, an arithmetic device that calculates the concentration of the specimen from the output signal, and an electrolyte item. An automatic analyzer comprising an electrolyte measuring device for measuring , which is characterized in that when a request is made to measure only electrolyte items as measurement items of a specimen, the results are output with priority over colorimetric items. 2. An automatic analysis device according to claim 1, characterized in that when a request is made to measure only electrolyte as a measurement item, the electrolyte measurement result is output preferentially only in the case of an emergency sample. Device.