JP2026020169A5 - - Google Patents
Info
- Publication number
- JP2026020169A5 JP2026020169A5 JP2025173688A JP2025173688A JP2026020169A5 JP 2026020169 A5 JP2026020169 A5 JP 2026020169A5 JP 2025173688 A JP2025173688 A JP 2025173688A JP 2025173688 A JP2025173688 A JP 2025173688A JP 2026020169 A5 JP2026020169 A5 JP 2026020169A5
- Authority
- JP
- Japan
- Prior art keywords
- fibrosis
- disease
- pharmaceutical composition
- composition according
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762535611P | 2017-07-21 | 2017-07-21 | |
| US62/535,611 | 2017-07-21 | ||
| JP2020502709A JP7383598B2 (ja) | 2017-07-21 | 2018-07-23 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
| PCT/US2018/043335 WO2019018855A1 (en) | 2017-07-21 | 2018-07-23 | ALPHA PROPELLER PROTEIN KINASE INHIBITORS ("COILED-COIL") ASSOCIATED WITH RHO |
| JP2023101681A JP7778745B2 (ja) | 2017-07-21 | 2023-06-21 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023101681A Division JP7778745B2 (ja) | 2017-07-21 | 2023-06-21 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2026020169A JP2026020169A (ja) | 2026-02-06 |
| JP2026020169A5 true JP2026020169A5 (https=) | 2026-03-31 |
Family
ID=65015613
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502709A Active JP7383598B2 (ja) | 2017-07-21 | 2018-07-23 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
| JP2023101681A Active JP7778745B2 (ja) | 2017-07-21 | 2023-06-21 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
| JP2025173688A Pending JP2026020169A (ja) | 2017-07-21 | 2025-10-15 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502709A Active JP7383598B2 (ja) | 2017-07-21 | 2018-07-23 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
| JP2023101681A Active JP7778745B2 (ja) | 2017-07-21 | 2023-06-21 | Ｒｈｏ関連コイルドコイル含有プロテインキナーゼの阻害剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11479533B2 (https=) |
| EP (1) | EP3654970A4 (https=) |
| JP (3) | JP7383598B2 (https=) |
| CN (1) | CN111050766A (https=) |
| CA (1) | CA3070115A1 (https=) |
| EA (1) | EA202090306A1 (https=) |
| WO (1) | WO2019018855A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019161162A1 (en) * | 2018-02-16 | 2019-08-22 | Constellation Pharmaceuticals, Inc. | P300/cbp hat inhibitors |
| JP7531379B2 (ja) * | 2019-12-31 | 2024-08-09 | 財團法人工業技術研究院 | βアミノ酸誘導体、これを含むキナーゼ阻害剤および医薬組成物ならびにその使用 |
| CN111707830B (zh) * | 2020-07-16 | 2023-08-15 | 首都医科大学附属北京朝阳医院 | Rock激酶活性在辅助诊断肺损害中的应用 |
| CN111707832B (zh) * | 2020-07-16 | 2023-08-15 | 首都医科大学附属北京朝阳医院 | Rock激酶活性在辅助诊断肾损害中的应用 |
| US20240423998A1 (en) * | 2021-11-29 | 2024-12-26 | Woolsey Pharmaceuticals, Inc. | Methods of treating agitation and other dementia-associated behavioral symptoms |
| JPWO2024075838A1 (https=) * | 2022-10-07 | 2024-04-11 | ||
| WO2025017500A1 (en) * | 2023-07-17 | 2025-01-23 | Graviton Bioscience Bv | Formulations of rock2 inhibitors for cns disorders |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003053941A2 (en) | 2001-12-20 | 2003-07-03 | Bristol-Myers Squibb Company | Barbituric acid derivatives as inhibitors of tnf-alpha converting enzyme (tace) and/or matrix metalloproteinases |
| TW200306819A (en) | 2002-01-25 | 2003-12-01 | Vertex Pharma | Indazole compounds useful as protein kinase inhibitors |
| MXPA05003317A (es) | 2002-09-25 | 2005-07-05 | Memory Pharm Corp | Indazoles, benzotiazoles y benzoisotiazoles asi como preparacion y usos de los mismos. |
| US8211919B2 (en) | 2005-09-02 | 2012-07-03 | Astellas Pharma Inc. | Amide derivatives as rock inhibitors |
| JP2011507850A (ja) | 2007-12-21 | 2011-03-10 | ザ スクリプス リサーチ インスティチュート | Ｒｈｏキナーゼインヒビターとしてのアニリドおよびアナログ |
| CN105102448B (zh) * | 2013-02-28 | 2018-03-06 | 百时美施贵宝公司 | 作为rock1和rock2抑制剂的苯基吡唑衍生物 |
| EP3019475A1 (en) | 2013-07-08 | 2016-05-18 | Bristol-Myers Squibb Company | Aryl amide kinase inhibitors |
| WO2015070170A1 (en) * | 2013-11-08 | 2015-05-14 | The Translational Genomics Research Institute | Compounds for cognitive enhancement and methods of use thereof |
| JP2017523214A (ja) | 2014-08-05 | 2017-08-17 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | ヘテロ環キナーゼ阻害剤 |
| US11926596B2 (en) * | 2017-07-21 | 2024-03-12 | Kadmon Corporation, Llc | Inhibitors of Rho associated coiled-coil containing protein kinase |
| EP3675861A4 (en) * | 2017-09-01 | 2021-01-06 | Kadmon Corporation, LLC | ALPHA SUPERWINDING PROTEIN KINASE INHIBITORS ("COILED-COIL") ASSOCIATED WITH RHO |
-
2018
- 2018-07-23 WO PCT/US2018/043335 patent/WO2019018855A1/en not_active Ceased
- 2018-07-23 EP EP18834641.5A patent/EP3654970A4/en active Pending
- 2018-07-23 JP JP2020502709A patent/JP7383598B2/ja active Active
- 2018-07-23 EA EA202090306A patent/EA202090306A1/ru unknown
- 2018-07-23 CN CN201880049759.5A patent/CN111050766A/zh active Pending
- 2018-07-23 US US16/632,662 patent/US11479533B2/en active Active
- 2018-07-23 CA CA3070115A patent/CA3070115A1/en active Pending
-
2023
- 2023-06-21 JP JP2023101681A patent/JP7778745B2/ja active Active
-
2025
- 2025-10-15 JP JP2025173688A patent/JP2026020169A/ja active Pending
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