JP2025530308A - 高純度及び高安定性のタンパク質の製造方法 - Google Patents

高純度及び高安定性のタンパク質の製造方法

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Publication number
JP2025530308A
JP2025530308A JP2025514802A JP2025514802A JP2025530308A JP 2025530308 A JP2025530308 A JP 2025530308A JP 2025514802 A JP2025514802 A JP 2025514802A JP 2025514802 A JP2025514802 A JP 2025514802A JP 2025530308 A JP2025530308 A JP 2025530308A
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JP
Japan
Prior art keywords
albumin
human albumin
recombinant human
exchange chromatography
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025514802A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025530308A5 (https=
Inventor
▲イ▼ 項
志蕾 岳
文▲ブン▼ 董
廷臣 管
Original Assignee
通化安睿特生物製薬股▲フェン▼有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 通化安睿特生物製薬股▲フェン▼有限公司 filed Critical 通化安睿特生物製薬股▲フェン▼有限公司
Publication of JP2025530308A publication Critical patent/JP2025530308A/ja
Publication of JP2025530308A5 publication Critical patent/JP2025530308A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2025514802A 2022-10-24 2023-08-28 高純度及び高安定性のタンパク質の製造方法 Pending JP2025530308A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202211301410.0A CN115677848A (zh) 2022-10-24 2022-10-24 一种制备高纯度高稳定性蛋白质的方法
CN202211301410.0 2022-10-24
PCT/CN2023/115220 WO2024087860A1 (zh) 2022-10-24 2023-08-28 一种制备高纯度高稳定性蛋白质的方法

Publications (2)

Publication Number Publication Date
JP2025530308A true JP2025530308A (ja) 2025-09-11
JP2025530308A5 JP2025530308A5 (https=) 2026-04-17

Family

ID=85065784

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025514802A Pending JP2025530308A (ja) 2022-10-24 2023-08-28 高純度及び高安定性のタンパク質の製造方法

Country Status (6)

Country Link
US (1) US20260098079A1 (https=)
EP (1) EP4610276A1 (https=)
JP (1) JP2025530308A (https=)
KR (1) KR20250088510A (https=)
CN (1) CN115677848A (https=)
WO (1) WO2024087860A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115677848A (zh) * 2022-10-24 2023-02-03 通化安睿特生物制药股份有限公司 一种制备高纯度高稳定性蛋白质的方法
CN118681001B (zh) * 2024-08-19 2024-12-06 通化安睿特生物制药股份有限公司 一种含人白蛋白和葡萄糖的透析液及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112516291A (zh) * 2019-09-17 2021-03-19 通化安睿特生物制药股份有限公司 含人白蛋白的制剂及其制备方法
CN113831405A (zh) * 2021-11-17 2021-12-24 华兰生物工程重庆有限公司 一种人血白蛋白的纯化方法
WO2022120547A1 (zh) * 2020-12-08 2022-06-16 通化安睿特生物制药股份有限公司 纯化重组蛋白的方法
JP2026509525A (ja) * 2023-03-16 2026-03-19 ユニヴァーシティ・オヴ・サンダーランド 創傷ドレッシング材

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
AU2016228806B2 (en) * 2015-03-12 2020-10-22 Medimmune, Llc Method of purifying albumin-fusion proteins
CN115677848A (zh) * 2022-10-24 2023-02-03 通化安睿特生物制药股份有限公司 一种制备高纯度高稳定性蛋白质的方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112516291A (zh) * 2019-09-17 2021-03-19 通化安睿特生物制药股份有限公司 含人白蛋白的制剂及其制备方法
WO2022120547A1 (zh) * 2020-12-08 2022-06-16 通化安睿特生物制药股份有限公司 纯化重组蛋白的方法
CN113831405A (zh) * 2021-11-17 2021-12-24 华兰生物工程重庆有限公司 一种人血白蛋白的纯化方法
JP2026509525A (ja) * 2023-03-16 2026-03-19 ユニヴァーシティ・オヴ・サンダーランド 創傷ドレッシング材

Also Published As

Publication number Publication date
KR20250088510A (ko) 2025-06-17
US20260098079A1 (en) 2026-04-09
WO2024087860A1 (zh) 2024-05-02
EP4610276A1 (en) 2025-09-03
CN115677848A (zh) 2023-02-03

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