JP2025516583A5 - - Google Patents
Info
- Publication number
- JP2025516583A5 JP2025516583A5 JP2024566316A JP2024566316A JP2025516583A5 JP 2025516583 A5 JP2025516583 A5 JP 2025516583A5 JP 2024566316 A JP2024566316 A JP 2024566316A JP 2024566316 A JP2024566316 A JP 2024566316A JP 2025516583 A5 JP2025516583 A5 JP 2025516583A5
- Authority
- JP
- Japan
- Prior art keywords
- capsid protein
- modified
- targeting peptide
- pharmaceutical composition
- approximately
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263340823P | 2022-05-11 | 2022-05-11 | |
| US63/340,823 | 2022-05-11 | ||
| US202263342324P | 2022-05-16 | 2022-05-16 | |
| US63/342,324 | 2022-05-16 | ||
| PCT/US2023/021905 WO2023220287A1 (en) | 2022-05-11 | 2023-05-11 | Adeno-associated viral vectors for targeting deep brain structures |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025516583A JP2025516583A (ja) | 2025-05-30 |
| JP2025516583A5 true JP2025516583A5 (enExample) | 2026-05-18 |
Family
ID=88730946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024566316A Pending JP2025516583A (ja) | 2022-05-11 | 2023-05-11 | 脳深部構造を標的とするアデノ随伴ウイルスベクター |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20260183425A1 (enExample) |
| EP (1) | EP4522272A4 (enExample) |
| JP (1) | JP2025516583A (enExample) |
| KR (1) | KR20250031153A (enExample) |
| CN (1) | CN119654334A (enExample) |
| AU (1) | AU2023269646A1 (enExample) |
| CA (1) | CA3252951A1 (enExample) |
| CO (1) | CO2024016255A2 (enExample) |
| IL (1) | IL316908A (enExample) |
| MX (1) | MX2024013890A (enExample) |
| WO (1) | WO2023220287A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4570260A1 (en) * | 2023-12-14 | 2025-06-18 | Medizinische Hochschule Hannover | Viral vector for transduction of adipocytes |
| WO2025231406A1 (en) * | 2024-05-02 | 2025-11-06 | The Children's Hospital Of Philadelphia | Methods to increase transduction of ependyma cells in brain |
| WO2025231387A1 (en) * | 2024-05-02 | 2025-11-06 | The Children's Hospital Of Philadelphia | Globus pallidus route of administration for deep brain gene therapies |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6342886B2 (ja) * | 2012-04-18 | 2018-06-13 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアＴｈｅ Ｃｈｉｌｄｒｅｎ’Ｓ Ｈｏｓｐｉｔａｌ Ｏｆ Ｐｈｉｌａｄｅｌｐｈｉａ | Ａａｖカプシドバリアントを使用した高効率な遺伝子導入のための組成物及び方法 |
| SI3645551T1 (sl) * | 2017-06-27 | 2024-06-28 | Regeneron Pharmaceuticals, Inc. | S tropizmi spremenjeni rekombinantni virusni vektorji in njihova uporaba za tarčni vnos genetskega materiala v človeške celice |
| US20220096574A1 (en) * | 2019-01-29 | 2022-03-31 | Holobiome, Inc. | Methods and compositions for treating and preventing central nervous system disorders and other conditions caused by gut microbial dysbiosis |
| TW202111127A (zh) * | 2019-07-24 | 2021-03-16 | 美商航海家醫療公司 | 用於治療亨丁頓舞蹈症之組合物及方法 |
| WO2021025995A1 (en) * | 2019-08-02 | 2021-02-11 | Voyager Therapeutics, Inc. | Aav variants with enhanced tropism |
| CN115023242B (zh) * | 2019-11-22 | 2025-03-14 | 费城儿童医院 | 腺相关病毒载体变体 |
-
2023
- 2023-05-11 EP EP23804269.1A patent/EP4522272A4/en active Pending
- 2023-05-11 WO PCT/US2023/021905 patent/WO2023220287A1/en not_active Ceased
- 2023-05-11 CN CN202380045864.2A patent/CN119654334A/zh active Pending
- 2023-05-11 JP JP2024566316A patent/JP2025516583A/ja active Pending
- 2023-05-11 IL IL316908A patent/IL316908A/en unknown
- 2023-05-11 AU AU2023269646A patent/AU2023269646A1/en active Pending
- 2023-05-11 US US18/863,862 patent/US20260183425A1/en active Pending
- 2023-05-11 CA CA3252951A patent/CA3252951A1/en active Pending
- 2023-05-11 KR KR1020247040677A patent/KR20250031153A/ko active Pending
-
2024
- 2024-11-08 MX MX2024013890A patent/MX2024013890A/es unknown
- 2024-11-28 CO CONC2024/0016255A patent/CO2024016255A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021520203A (ja) | 減少した肝臓向性を有するＡＡＶ９とＡＡＶｒｈ７４とのハイブリッド組換えアデノ随伴ウイルス血清型 | |
| JP2023514242A5 (enExample) | ||
| JP2021534809A (ja) | Ａａｖカプシドの向性の再指向化 | |
| RU2017121593A (ru) | Векторы aav, нацеленные на центральную нервную систему | |
| JP7663492B2 (ja) | 細胞透過性ペプチド | |
| US20260091120A1 (en) | Cell-penetrating peptides | |
| JP2022520232A5 (enExample) | ||
| JP2024517710A5 (enExample) | ||
| US9809823B2 (en) | DNA aptamers for promoting remyelination | |
| WO2003045439A1 (en) | Genetic remedies for neurodegenerative diseases | |
| JP2024515459A5 (enExample) | ||
| AU2024276934A1 (en) | Adeno-associated virus capsid protein, adeno-associated virus containing same, vector and use thereof | |
| JP2025513066A5 (enExample) | ||
| JP2025534332A (ja) | 治療用核酸及びその使用方法 | |
| CN116368157A (zh) | 用于溶解蛋白质聚集体的组合物和方法 | |
| TW202523846A (zh) | 用於治療與共濟蛋白(frataxin)不足有關之疾病之組合物及方法 | |
| Peng et al. | Viral-mediated gene therapy in pediatric neurological disorders | |
| JP2024527742A5 (enExample) | ||
| US20230330267A1 (en) | Novel engineered capsid serotype of recombinant adeno-associated viral vector with enhanced transduction efficiency and widespread distribution in the brain | |
| JP2025510975A5 (enExample) | ||
| AU2025248711A1 (en) | Gene Therapy For Addiction Disorders | |
| JP2024501022A5 (enExample) | ||
| CN113117096B (zh) | 一种NCAM模拟肽修饰的pH敏感基因仿生递释系统及其应用 | |
| WO2022055320A1 (ko) | 표적화된 유전자 전달을 위한 아데노-부속 바이러스 벡터 | |
| JP2022552003A5 (enExample) |