JP2025513851A - 遺伝子治療のためのｉｒａｋ４モジュレーターの使用 - Google Patents

遺伝子治療のためのｉｒａｋ４モジュレーターの使用 Download PDF

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JP2025513851A
JP2025513851A JP2024560405A JP2024560405A JP2025513851A JP 2025513851 A JP2025513851 A JP 2025513851A JP 2024560405 A JP2024560405 A JP 2024560405A JP 2024560405 A JP2024560405 A JP 2024560405A JP 2025513851 A JP2025513851 A JP 2025513851A
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gene therapy
capsid
irak
aav
individual
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JP2025513851A5 (https=
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ソウラブ・ロイ・チョードリー
モナ・モトワニ
クリスティアン・ミュラー
ジョン・リード
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Genzyme Corp
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Genzyme Corp
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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JP2024560405A 2022-04-12 2023-04-12 遺伝子治療のためのｉｒａｋ４モジュレーターの使用 Pending JP2025513851A (ja)

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US202263330245P 2022-04-12 2022-04-12
US63/330,245 2022-04-12
PCT/US2023/065689 WO2023201274A1 (en) 2022-04-12 2023-04-12 Use of an irak4 modulator for gene therapy

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JP2025513851A true JP2025513851A (ja) 2025-04-30
JP2025513851A5 JP2025513851A5 (https=) 2026-04-20

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US (1) US20230405014A1 (https=)
EP (1) EP4508226A1 (https=)
JP (1) JP2025513851A (https=)
KR (1) KR20250004738A (https=)
CN (1) CN119343458A (https=)
AU (1) AU2023253700A1 (https=)
CA (1) CA3248216A1 (https=)
IL (1) IL316222A (https=)
MX (1) MX2024012617A (https=)
TW (1) TW202402329A (https=)
WO (1) WO2023201274A1 (https=)

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KR20220145325A (ko) 2019-12-17 2022-10-28 카이메라 쎄라퓨틱스 인코포레이티드 Irak 분해제 및 이의 용도
TW202535949A (zh) 2023-12-20 2025-09-16 美商必治妥美雅史谷比公司 靶向IL-18受體β(IL-18RB)之抗體及相關方法
WO2025158385A1 (en) * 2024-01-25 2025-07-31 Genzyme Corporation Pegylated il-2 for suppressing adaptive immune response to gene therapy

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TW202210483A (zh) 2020-06-03 2022-03-16 美商凱麥拉醫療公司 Irak降解劑之結晶型
US20230250110A1 (en) 2020-06-03 2023-08-10 Kymera Therapeutics, Inc. Deuterated irak degraders and uses thereof

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