CN119343458A - Irak4调节剂用于基因疗法的用途 - Google Patents

Irak4调节剂用于基因疗法的用途 Download PDF

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Publication number
CN119343458A
CN119343458A CN202380044027.8A CN202380044027A CN119343458A CN 119343458 A CN119343458 A CN 119343458A CN 202380044027 A CN202380044027 A CN 202380044027A CN 119343458 A CN119343458 A CN 119343458A
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China
Prior art keywords
capsid
irak
aav
gene therapy
individual
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Pending
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CN202380044027.8A
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English (en)
Chinese (zh)
Inventor
S·R·丘杜里
M·莫特瓦尼
C·穆埃勒
J·里德
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Genzyme Corp
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Genzyme Corp
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Publication of CN119343458A publication Critical patent/CN119343458A/zh
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
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CN202380044027.8A 2022-04-12 2023-04-12 Irak4调节剂用于基因疗法的用途 Pending CN119343458A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263330245P 2022-04-12 2022-04-12
US63/330,245 2022-04-12
PCT/US2023/065689 WO2023201274A1 (en) 2022-04-12 2023-04-12 Use of an irak4 modulator for gene therapy

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CN119343458A true CN119343458A (zh) 2025-01-21

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US (1) US20230405014A1 (https=)
EP (1) EP4508226A1 (https=)
JP (1) JP2025513851A (https=)
KR (1) KR20250004738A (https=)
CN (1) CN119343458A (https=)
AU (1) AU2023253700A1 (https=)
CA (1) CA3248216A1 (https=)
IL (1) IL316222A (https=)
MX (1) MX2024012617A (https=)
TW (1) TW202402329A (https=)
WO (1) WO2023201274A1 (https=)

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KR20220145325A (ko) 2019-12-17 2022-10-28 카이메라 쎄라퓨틱스 인코포레이티드 Irak 분해제 및 이의 용도
TW202535949A (zh) 2023-12-20 2025-09-16 美商必治妥美雅史谷比公司 靶向IL-18受體β(IL-18RB)之抗體及相關方法
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