JP2025509106A5 - - Google Patents
Info
- Publication number
- JP2025509106A5 JP2025509106A5 JP2024549763A JP2024549763A JP2025509106A5 JP 2025509106 A5 JP2025509106 A5 JP 2025509106A5 JP 2024549763 A JP2024549763 A JP 2024549763A JP 2024549763 A JP2024549763 A JP 2024549763A JP 2025509106 A5 JP2025509106 A5 JP 2025509106A5
- Authority
- JP
- Japan
- Prior art keywords
- plasmid vector
- orf
- vector according
- protein
- orf encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TH2201001686 | 2022-03-21 | ||
| TH2201001686 | 2022-03-21 | ||
| PCT/TH2023/000003 WO2023182948A1 (en) | 2022-03-21 | 2023-03-21 | Internal ribosome entry site (ires), plasmid vector and circular mrna for enhancing protein expression |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025509106A JP2025509106A (ja) | 2025-04-11 |
| JP2025509106A5 true JP2025509106A5 (https=) | 2026-04-01 |
Family
ID=86054332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024549763A Pending JP2025509106A (ja) | 2022-03-21 | 2023-03-21 | タンパク質発現を増強するための、配列内リボソーム進入部位（ＩＲＥＳ）、プラスミドベクター及び環状ｍＲＮＡ |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250243507A1 (https=) |
| EP (1) | EP4496598A1 (https=) |
| JP (1) | JP2025509106A (https=) |
| CN (1) | CN118871134A (https=) |
| AU (1) | AU2023240827A1 (https=) |
| WO (1) | WO2023182948A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2024234874A1 (en) | 2023-03-15 | 2025-10-09 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025128871A2 (en) | 2023-12-13 | 2025-06-19 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2025174765A1 (en) | 2024-02-12 | 2025-08-21 | Renagade Therapeutics Management Inc. | Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents |
| WO2026006644A1 (en) * | 2024-06-26 | 2026-01-02 | Emervax, Inc. | Circular mrna yellow fever vaccine |
| WO2026006593A1 (en) | 2024-06-28 | 2026-01-02 | Orna Therapeutics, Inc. | Synthetic internal ribosome entry sites |
| CN119464284B (zh) * | 2024-09-29 | 2026-02-13 | 复旦大学附属肿瘤医院 | 一种用于免疫细胞高效蛋白表达的环形rna疫苗平台及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2996697B1 (en) | 2013-05-15 | 2019-06-26 | Robert Kruse | Intracellular translation of circular rna |
| CN112399860B (zh) | 2018-06-06 | 2024-08-16 | 麻省理工学院 | 用于在真核细胞中翻译的环状rna |
| BR112021023411A2 (pt) | 2019-05-22 | 2022-02-01 | Massachusetts Inst Technology | Composições e métodos de rna circular |
| CN114981409A (zh) * | 2019-09-03 | 2022-08-30 | 美洛德生物医药公司 | 用于基因组整合的方法和组合物 |
| JP7851254B2 (ja) * | 2020-03-20 | 2026-04-24 | オルナ セラピューティクス インコーポレイテッド | 環状ｒｎａ組成物及び方法 |
| AU2021269137A1 (en) * | 2020-05-08 | 2022-12-15 | Orna Therapeutics, Inc. | Circular RNA compositions and methods |
| WO2021236855A1 (en) * | 2020-05-19 | 2021-11-25 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
| IL298362A (en) * | 2020-05-20 | 2023-01-01 | Flagship Pioneering Innovations Vi Llc | Coronavirus antigen compositions and their uses |
| AU2021300378A1 (en) * | 2020-07-01 | 2023-01-19 | Elevatebio Technologies, Inc. | Compositions and methods for cellular reprogramming using circular RNA |
| US20230346921A1 (en) * | 2020-08-21 | 2023-11-02 | Peking University | Circular rna vaccines and methods of use thereof |
| AU2021336976A1 (en) * | 2020-09-03 | 2023-03-23 | Flagship Pioneering Innovations Vi, Llc | Immunogenic compositions and uses thereof |
| BR112023023642A2 (pt) * | 2021-05-11 | 2024-01-30 | Myeloid Therapeutics Inc | Métodos e composições para integração genômica |
| CN115404240A (zh) * | 2021-05-28 | 2022-11-29 | 上海环码生物医药有限公司 | 制备环形rna的构建体、方法及其用途 |
| TW202317767A (zh) * | 2021-06-10 | 2023-05-01 | 美商歐納醫療公司 | 環狀rna組合物及方法 |
| CN115702940A (zh) * | 2021-08-05 | 2023-02-17 | 苏州科锐迈德生物医药科技有限公司 | 包含环状rna分子的制剂在制备治疗肿瘤的药物中的应用 |
-
2023
- 2023-03-21 WO PCT/TH2023/000003 patent/WO2023182948A1/en not_active Ceased
- 2023-03-21 EP EP23718371.0A patent/EP4496598A1/en active Pending
- 2023-03-21 US US18/848,164 patent/US20250243507A1/en active Pending
- 2023-03-21 JP JP2024549763A patent/JP2025509106A/ja active Pending
- 2023-03-21 AU AU2023240827A patent/AU2023240827A1/en active Pending
- 2023-03-21 CN CN202380027077.5A patent/CN118871134A/zh active Pending
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