JP2025507372A5 - - Google Patents

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Publication number
JP2025507372A5
JP2025507372A5 JP2024547599A JP2024547599A JP2025507372A5 JP 2025507372 A5 JP2025507372 A5 JP 2025507372A5 JP 2024547599 A JP2024547599 A JP 2024547599A JP 2024547599 A JP2024547599 A JP 2024547599A JP 2025507372 A5 JP2025507372 A5 JP 2025507372A5
Authority
JP
Japan
Prior art keywords
dsrna agent
agent according
nucleotides
nucleotide
tau
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024547599A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025507372A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/062440 external-priority patent/WO2023154900A2/en
Publication of JP2025507372A publication Critical patent/JP2025507372A/ja
Publication of JP2025507372A5 publication Critical patent/JP2025507372A5/ja
Pending legal-status Critical Current

Links

JP2024547599A 2022-02-11 2023-02-10 微小管関連タンパク質タウ（ＭＡＰＴ）ｉＲＮＡ剤組成物およびその使用方法 Pending JP2025507372A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263309399P 2022-02-11 2022-02-11
US63/309,399 2022-02-11
US202263322618P 2022-03-22 2022-03-22
US63/322,618 2022-03-22
PCT/US2023/062440 WO2023154900A2 (en) 2022-02-11 2023-02-10 Microtubule associated protein tau (mapt) irna agent compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2025507372A JP2025507372A (ja) 2025-03-18
JP2025507372A5 true JP2025507372A5 (https=) 2026-02-17

Family

ID=87565165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024547599A Pending JP2025507372A (ja) 2022-02-11 2023-02-10 微小管関連タンパク質タウ（ＭＡＰＴ）ｉＲＮＡ剤組成物およびその使用方法

Country Status (4)

Country Link
US (1) US20250171777A1 (https=)
EP (1) EP4476338A2 (https=)
JP (1) JP2025507372A (https=)
WO (1) WO2023154900A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12551569B2 (en) 2024-03-31 2026-02-17 Arrowhead Pharmaceuticals, Inc. RNAi agents for inhibiting expression of microtubule associated protein tau (MAPT), compositions thereof, and methods of use
WO2026048822A1 (ja) * 2024-08-30 2026-03-05 東亞合成株式会社 Ｍａｐｔ ｒｎａ配列に基づく新規二本鎖ｒｎａ及びその利用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2145014B1 (en) 2007-04-05 2012-12-12 The J. David Gladstone Institutes Agents that reduce neuronal overexcitation
US10513701B2 (en) * 2015-03-25 2019-12-24 Università Degli Studi Di Trento RNA interference mediated therapy for neurodegenerative diseases
AU2021246024A1 (en) 2020-03-30 2022-10-27 Alnylam Pharmaceuticals, Inc. Microtubule associated protein Tau (MAPT) iRNA agent compositions and methods of use thereof

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