JP2025506318A5 - - Google Patents
Info
- Publication number
- JP2025506318A5 JP2025506318A5 JP2023547446A JP2023547446A JP2025506318A5 JP 2025506318 A5 JP2025506318 A5 JP 2025506318A5 JP 2023547446 A JP2023547446 A JP 2023547446A JP 2023547446 A JP2023547446 A JP 2023547446A JP 2025506318 A5 JP2025506318 A5 JP 2025506318A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- variable region
- chain variable
- antibody
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210132762.1A CN114181310B (zh) | 2022-02-14 | 2022-02-14 | 抗tigit抗体、其药物组合物及用途 |
| CN202210132762.1 | 2022-02-14 | ||
| PCT/CN2023/075862 WO2023151693A1 (zh) | 2022-02-14 | 2023-02-14 | 包含抗tigit抗体和抗pd-1-抗vegfa双特异性抗体的药物组合物及用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025506318A JP2025506318A (ja) | 2025-03-11 |
| JP2025506318A5 true JP2025506318A5 (https=) | 2026-02-27 |
Family
ID=80607015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023547446A Pending JP2025506318A (ja) | 2022-02-14 | 2023-02-14 | 抗ｔｉｇｉｔ抗体と抗ｐｄ－１－抗ｖｅｇｆａ二重特異性抗体を含有する医薬組成物及び使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250034253A1 (https=) |
| EP (1) | EP4273170A4 (https=) |
| JP (1) | JP2025506318A (https=) |
| KR (1) | KR20240145470A (https=) |
| CN (1) | CN114181310B (https=) |
| AU (1) | AU2023217806A1 (https=) |
| CA (1) | CA3208430A1 (https=) |
| IL (1) | IL314785A (https=) |
| MX (1) | MX2024009976A (https=) |
| WO (1) | WO2023151693A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112022002028A2 (pt) * | 2019-08-02 | 2022-04-12 | Cttq Akeso Shanghai Biomed Tech Co Ltd | Anticorpo anti-pd-1 e uso farmacêutico do mesmo |
| IL310217A (en) * | 2021-07-23 | 2024-03-01 | Akeso Biopharma Inc | Pharmaceutical composition and use |
| WO2023020625A1 (zh) * | 2021-08-20 | 2023-02-23 | 中山康方生物医药有限公司 | 包含抗TIGIT抗体和TGF-βR的融合蛋白、其药物组合物及用途 |
| CN114181310B (zh) * | 2022-02-14 | 2022-07-05 | 中山康方生物医药有限公司 | 抗tigit抗体、其药物组合物及用途 |
| CN116284395B (zh) * | 2022-12-12 | 2024-11-08 | 合肥天港免疫药物有限公司 | 抗cd155的抗体及其应用 |
| CN116143923B (zh) * | 2022-12-30 | 2025-11-11 | 合肥天港免疫药物有限公司 | 高亲和力tigit抗体及其应用 |
| KR20250151519A (ko) * | 2023-02-20 | 2025-10-21 | 아케소 바이오파마 컴퍼니 리미티드 | TGF-βRII 세포 외 영역 단편을 포함하는 융합 단백질, 및 이의 약제학적 조성물, 및 이의 용도 |
| WO2025056056A1 (zh) * | 2023-09-14 | 2025-03-20 | 中山康方生物医药有限公司 | 药物组合及用途 |
| CN120530139A (zh) * | 2023-12-29 | 2025-08-22 | 成都优洛生物科技有限公司 | 抗tl1a抗体或其抗原结合片段及应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5747654A (en) | 1993-06-14 | 1998-05-05 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant disulfide-stabilized polypeptide fragments having binding specificity |
| CA2611861C (en) * | 2005-06-08 | 2017-11-28 | The Brigham And Women's Hospital, Inc. | Methods and compositions for the treatment of persistent infections |
| EP3255060A1 (en) * | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| KR102236367B1 (ko) | 2013-07-26 | 2021-04-05 | 삼성전자주식회사 | DARPin을 포함하는 이중 특이 키메라 단백질 |
| CA2942546C (en) | 2014-03-17 | 2022-11-22 | Mitsubishi Tanabe Pharma Corporation | Antibody-fynomer conjugates |
| MD4733C1 (ro) * | 2014-08-19 | 2021-07-31 | Merck Sharp & Dohme Corp | Anticorpi anti-TIGIT |
| PE20181046A1 (es) | 2015-09-25 | 2018-07-03 | Genentech Inc | Anticuerpos anti-tigit y metodos de uso |
| LT3618863T (lt) * | 2017-05-01 | 2023-10-10 | Agenus Inc. | Anti-tigit antikūnai ir jų panaudojimo būdai |
| JP7317272B2 (ja) * | 2017-09-29 | 2023-07-31 | ジエンス ヘンルイ メデイシンカンパニー リミテッド | Ｔｉｇｉｔ抗体、その抗原結合断片及びその医療用途 本願は、２０１９年９月２９日に出願された出願番号ｃｎ２０１７１０９０８５６５．３に基づいたものであり、その優先権を主張する。その開示は、その全体が参照により本明細書に組み込まれる。 |
| CN109053895B (zh) * | 2018-08-30 | 2020-06-09 | 中山康方生物医药有限公司 | 抗pd-1-抗vegfa的双功能抗体、其药物组合物及其用途 |
| CN111196852A (zh) * | 2018-11-16 | 2020-05-26 | 四川科伦博泰生物医药股份有限公司 | 抗tigit抗体及其用途 |
| PH12022551278A1 (en) * | 2019-11-25 | 2023-11-20 | Akeso Biopharma Inc | Anti-pd-1-anti-vegfa bispecific antibody, pharmaceutical composition and use thereof |
| CN110960543A (zh) * | 2019-12-10 | 2020-04-07 | 安徽瀚海博兴生物技术有限公司 | 一种联合抗vegf-抗pd1双特异性抗体用于制备抗癌药物 |
| CN113214400B (zh) * | 2020-01-21 | 2022-11-08 | 甫康（上海）健康科技有限责任公司 | 一种双特异性抗pd-l1/vegf抗体及其用途 |
| TW202142230A (zh) * | 2020-01-27 | 2021-11-16 | 美商建南德克公司 | 用於以抗ｔｉｇｉｔ拮抗體抗體治療癌症之方法 |
| WO2021263085A2 (en) * | 2020-06-25 | 2021-12-30 | Arch Oncology, Inc. | Combination therapy for the treatment of solid and hematological cancers |
| EP4192883A4 (en) * | 2020-08-05 | 2024-12-04 | Crystal Bioscience Inc. | Anti-tigit antibody and methods of use thereof |
| US11028172B1 (en) * | 2020-11-10 | 2021-06-08 | Lepu Biopharma Co., Ltd. | Anti-TIGIT antibodies and uses thereof |
| CN114181310B (zh) * | 2022-02-14 | 2022-07-05 | 中山康方生物医药有限公司 | 抗tigit抗体、其药物组合物及用途 |
-
2022
- 2022-02-14 CN CN202210132762.1A patent/CN114181310B/zh active Active
-
2023
- 2023-02-14 AU AU2023217806A patent/AU2023217806A1/en active Pending
- 2023-02-14 US US18/264,138 patent/US20250034253A1/en active Pending
- 2023-02-14 KR KR1020247026551A patent/KR20240145470A/ko active Pending
- 2023-02-14 CA CA3208430A patent/CA3208430A1/en active Pending
- 2023-02-14 MX MX2024009976A patent/MX2024009976A/es unknown
- 2023-02-14 JP JP2023547446A patent/JP2025506318A/ja active Pending
- 2023-02-14 WO PCT/CN2023/075862 patent/WO2023151693A1/zh not_active Ceased
- 2023-02-14 EP EP23745373.3A patent/EP4273170A4/en active Pending
- 2023-02-14 IL IL314785A patent/IL314785A/en unknown
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