JP2025505892A5 - - Google Patents

Info

Publication number
JP2025505892A5
JP2025505892A5 JP2024543870A JP2024543870A JP2025505892A5 JP 2025505892 A5 JP2025505892 A5 JP 2025505892A5 JP 2024543870 A JP2024543870 A JP 2024543870A JP 2024543870 A JP2024543870 A JP 2024543870A JP 2025505892 A5 JP2025505892 A5 JP 2025505892A5
Authority
JP
Japan
Prior art keywords
compound
solvent
alkyl
base
benzyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024543870A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025505892A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/011636 external-priority patent/WO2023146973A1/en
Publication of JP2025505892A publication Critical patent/JP2025505892A/ja
Publication of JP2025505892A5 publication Critical patent/JP2025505892A5/ja
Pending legal-status Critical Current

Links

JP2024543870A 2022-01-26 2023-01-26 Kif18a阻害剤の合成 Pending JP2025505892A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263303470P 2022-01-26 2022-01-26
US63/303,470 2022-01-26
PCT/US2023/011636 WO2023146973A1 (en) 2022-01-26 2023-01-26 Synthesis of a kif18a inhibitor

Publications (2)

Publication Number Publication Date
JP2025505892A JP2025505892A (ja) 2025-03-03
JP2025505892A5 true JP2025505892A5 (https=) 2026-01-30

Family

ID=85328813

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024543870A Pending JP2025505892A (ja) 2022-01-26 2023-01-26 Kif18a阻害剤の合成

Country Status (12)

Country Link
US (1) US20250129050A1 (https=)
EP (1) EP4469437A1 (https=)
JP (1) JP2025505892A (https=)
KR (1) KR20240144140A (https=)
CN (1) CN118922406A (https=)
AR (1) AR128353A1 (https=)
AU (1) AU2023211589A1 (https=)
CA (1) CA3248925A1 (https=)
IL (1) IL314221A (https=)
MX (1) MX2024009163A (https=)
TW (1) TW202342451A (https=)
WO (1) WO2023146973A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA54543A (fr) 2018-12-20 2022-03-30 Amgen Inc Inhibiteurs de kif18a
TW202416973A (zh) 2022-08-18 2024-05-01 美商雅客森醫療公司 Kif18a抑制劑及其用途
CN115925589A (zh) * 2022-12-26 2023-04-07 诚达药业股份有限公司 一种脂肪族亚磺酸钙盐及其制备方法
WO2025036479A1 (zh) * 2023-08-16 2025-02-20 上海湃隆生物科技有限公司 驱动蛋白kif18a抑制剂及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA54543A (fr) * 2018-12-20 2022-03-30 Amgen Inc Inhibiteurs de kif18a
MX2022012992A (es) * 2020-04-14 2022-11-08 Amgen Inc Inhibidores de kif18a para el tratamiento de enfermedades neoplasicas.

Similar Documents

Publication Publication Date Title
JP2025505892A5 (https=)
JP4594317B2 (ja) アミノクロトニル化合物の調製方法
US9035061B2 (en) Process for preparing a biphenyl-2-ylcarbamic acid
KR20230117416A (ko) 아미노피리미딘계 fak 억제제 화합물의 합성 방법
EP3097096A1 (en) 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1- (arylsulfonyl)-3,4-dihydropyrimidin-2(1h)-one and processes for their preparation
JP6556293B2 (ja) 純粋なニロチニブ及びその塩の調製のための方法
CN116730921A (zh) Ag-10的制备方法、其中间体及其盐
TW202342451A (zh) Kif18a抑制劑之合成
KR102698832B1 (ko) 엑토인의 제조방법
MXPA04008109A (es) Metodo para preparar cloruro de bencisoxasol metano sulfonilo y su amidacion para formar zonisamida.
CN105593218A (zh) 用于制备苯并异噻唑啉酮的方法
CN103755651A (zh) 2-(5-溴-4-(4-环丙基萘-1-基)-4h-1,2,4-三唑-3-基硫基)乙酸的盐的新晶型及其制备方法
KR20200110381A (ko) 술펜트라존의 합성 방법
US8729138B2 (en) Mixture of polyfluoroalkylsulfonamido alkyl amines
CS207750B2 (en) Method of making the n'-cyano-n'-alcyl-n-2-/5-methyl-1h-imidazol-4-yl/methyl thicethyl guanidines
TWI280243B (en) A process for the manufacture of the salts of sulfonylaminocarbonyl triazolinones
US8604208B2 (en) Polymorphs of sorafenib acid addition salts
HUT53878A (en) Process for producing substituted (quinoline-2-il-methoxy)-phenyl-n,n'-sulfonyl-carbamides and pharmaceutical preparations containing the compounds
KR100712234B1 (ko) 글리메피라이드의 제조방법
KR20200088570A (ko) 피마살탄 및 그의 제조 중간체의 제조방법
US20110237834A1 (en) Polyfluoroalkylsulfonamido alkyl halide intermediate
WO2025124936A1 (en) A process for making osimertinib
JP2014525422A (ja) [3−[(6−クロロ−3−ピリジニル)メチル]−2−チアゾリジニリデン]シアナミドを製造する方法
KR20140027921A (ko) 디(아릴아미노)아릴 화합물의 제조 방법 및 그 합성 중간체
EP1609792A1 (en) A process for the preparation of imiquimod and intermediates thereof