JP2025505642A5 - - Google Patents

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Publication number
JP2025505642A5
JP2025505642A5 JP2024546404A JP2024546404A JP2025505642A5 JP 2025505642 A5 JP2025505642 A5 JP 2025505642A5 JP 2024546404 A JP2024546404 A JP 2024546404A JP 2024546404 A JP2024546404 A JP 2024546404A JP 2025505642 A5 JP2025505642 A5 JP 2025505642A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
composition according
antibody
administered
dose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024546404A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025505642A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/051076 external-priority patent/WO2023148702A1/en
Publication of JP2025505642A publication Critical patent/JP2025505642A/ja
Publication of JP2025505642A5 publication Critical patent/JP2025505642A5/ja
Pending legal-status Critical Current

Links

JP2024546404A 2022-02-07 2023-02-07 Egfr/met二重特異性抗体で処置された患者における注入関連反応を低減するための方法 Pending JP2025505642A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263307375P 2022-02-07 2022-02-07
US63/307,375 2022-02-07
US202263389042P 2022-07-14 2022-07-14
US63/389,042 2022-07-14
PCT/IB2023/051076 WO2023148702A1 (en) 2022-02-07 2023-02-07 Methods for reducing infusion-related reactions in patients treated with egfr/met bispecific antibodies

Publications (2)

Publication Number Publication Date
JP2025505642A JP2025505642A (ja) 2025-02-28
JP2025505642A5 true JP2025505642A5 (https=) 2026-01-21

Family

ID=85278233

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024546404A Pending JP2025505642A (ja) 2022-02-07 2023-02-07 Egfr/met二重特異性抗体で処置された患者における注入関連反応を低減するための方法

Country Status (10)

Country Link
US (1) US20230250195A1 (https=)
EP (1) EP4476255A1 (https=)
JP (1) JP2025505642A (https=)
KR (1) KR20240146675A (https=)
AU (1) AU2023215753A1 (https=)
CA (1) CA3251417A1 (https=)
IL (1) IL314756A (https=)
MX (1) MX2024009701A (https=)
TW (1) TW202342057A (https=)
WO (1) WO2023148702A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025185602A1 (en) * 2024-03-05 2025-09-12 Hansoh Bio Llc Immunoconjugates and pharmaceutical uses thereof
WO2026038160A1 (en) * 2024-08-13 2026-02-19 Janssen Biotech, Inc. Methods for reducing infusion-related reactions in patients treated with egfr/met bispecific antibodies

Family Cites Families (28)

* Cited by examiner, † Cited by third party
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GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
EP3042964A1 (en) 2004-06-04 2016-07-13 Genentech, Inc. Egfr mutations
WO2006028936A2 (en) 2004-09-02 2006-03-16 Genentech, Inc. Heteromultimeric molecules
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
PT1999154E (pt) 2006-03-24 2013-01-24 Merck Patent Gmbh Domínios proteicos heterodiméricos modificados
JP2009541275A (ja) 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー/エス 二重特異性抗体の生産
KR20100058509A (ko) 2007-07-31 2010-06-03 메디뮨 엘엘씨 다중특이적 에피토프 결합 단백질 및 이의 용도
AU2008343589A1 (en) 2007-12-19 2009-07-09 Centocor Ortho Biotech Inc. Design and generation of human de novo pIX phage display libraries via fusion to pIX or pVII, vectors, antibodies and methods
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
WO2010129304A2 (en) 2009-04-27 2010-11-11 Oncomed Pharmaceuticals, Inc. Method for making heteromultimeric molecules
HRP20241208T1 (hr) 2010-04-20 2024-11-22 Genmab A/S Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
SG194802A1 (en) * 2011-05-16 2013-12-30 Genzyme Corp Induction of immune tolerance by using methotrexate
BR112014010580B1 (pt) 2011-11-04 2021-01-12 Zymeworks, Inc. constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado
MX361088B (es) 2012-11-21 2018-11-26 Janssen Biotech Inc Anticuerpos del receptor del factor de crecimiento epidérmico aislado/del receptor del factor de crecimiento de hepatocitos (egfr/c-met) biespecíficos.
HUE054848T2 (hu) 2014-10-13 2021-09-28 Yuhan Corp Vegyületek és készítmények EGFR mutáns kináz aktivitás módosítására
KR102771603B1 (ko) 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
US11879013B2 (en) * 2019-05-14 2024-01-23 Janssen Biotech, Inc. Combination therapies with bispecific anti-EGFR/c-Met antibodies and third generation EGFR tyrosine kinase inhibitors
AU2020284706A1 (en) * 2019-05-28 2021-12-16 Alligator Bioscience Ab Method of providing safe administration of an anti-CD40 antibody
WO2021245238A1 (en) * 2020-06-04 2021-12-09 Bioinvent International Ab Improving antibody tolerability associated with intravenous administration
US20230174677A1 (en) * 2021-11-16 2023-06-08 Janssen Biotech, Inc. Use of Approved Bispecific EGFR and Met Specific Antibody Drug Product to Treat Non-Small Cell Lung Cancer (NSCLCL)

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