JP2025503971A5 - - Google Patents

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Publication number
JP2025503971A5
JP2025503971A5 JP2024544447A JP2024544447A JP2025503971A5 JP 2025503971 A5 JP2025503971 A5 JP 2025503971A5 JP 2024544447 A JP2024544447 A JP 2024544447A JP 2024544447 A JP2024544447 A JP 2024544447A JP 2025503971 A5 JP2025503971 A5 JP 2025503971A5
Authority
JP
Japan
Prior art keywords
cancer
pharmaceutical composition
pharmaceutically acceptable
mta
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024544447A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503971A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/011658 external-priority patent/WO2023146989A1/en
Publication of JP2025503971A publication Critical patent/JP2025503971A/ja
Publication of JP2025503971A5 publication Critical patent/JP2025503971A5/ja
Pending legal-status Critical Current

Links

JP2024544447A 2022-01-26 2023-01-26 化合物及び使用方法 Pending JP2025503971A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263303497P 2022-01-26 2022-01-26
US63/303,497 2022-01-26
PCT/US2023/011658 WO2023146989A1 (en) 2022-01-26 2023-01-26 Compounds and methods of use

Publications (2)

Publication Number Publication Date
JP2025503971A JP2025503971A (ja) 2025-02-06
JP2025503971A5 true JP2025503971A5 (enExample) 2026-02-16

Family

ID=85382515

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024544447A Pending JP2025503971A (ja) 2022-01-26 2023-01-26 化合物及び使用方法

Country Status (4)

Country Link
US (1) US20250171432A1 (enExample)
EP (1) EP4469447A1 (enExample)
JP (1) JP2025503971A (enExample)
WO (1) WO2023146989A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117658980A (zh) * 2022-09-08 2024-03-08 郑州同源康医药有限公司 双环类prmt5抑制剂
CN120476118A (zh) * 2023-01-17 2025-08-12 苏州浦合医药科技有限公司 Prmt5-mta抑制剂
CN121241054A (zh) * 2023-04-14 2025-12-30 北京双鹤润创科技有限公司 氮杂环羰基稠环衍生物及其用途
CR20250446A (es) 2023-04-21 2025-12-02 Gilead Sciences Inc Inhibidores de prmt5 y usos de los mismos
WO2025217297A1 (en) 2024-04-09 2025-10-16 Tango Therapeutics, Inc. Prmt5 inhibitors for use in methods of treating mta-accumulating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040138A (en) 1995-09-15 2000-03-21 Affymetrix, Inc. Expression monitoring by hybridization to high density oligonucleotide arrays
WO2011079236A1 (en) 2009-12-22 2011-06-30 The Ohio State University Research Foundation Compositions and methods for cancer detection and treatment
WO2022026892A1 (en) * 2020-07-31 2022-02-03 Tango Therapeutics, Inc. Piperidin-1- yl-n-pyrydi ne-3-yl-2-oxoacet am ide derivatives useful for the treatment of mtap-deficient and/or mt a-accumulating cancers
EP4347569A4 (en) * 2021-06-02 2025-03-26 Ideaya Biosciences, Inc. Combination therapy comprising a mat2a inhibitor and a type ii prmt inhibitor

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