JP2025503546A - Ｉｌ－１０およびキメラ抗原受容体を発現するｃｄ４＋ｔ細胞およびその使用 - Google Patents

Ｉｌ－１０およびキメラ抗原受容体を発現するｃｄ４＋ｔ細胞およびその使用 Download PDF

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JP2025503546A
JP2025503546A JP2024539566A JP2024539566A JP2025503546A JP 2025503546 A JP2025503546 A JP 2025503546A JP 2024539566 A JP2024539566 A JP 2024539566A JP 2024539566 A JP2024539566 A JP 2024539566A JP 2025503546 A JP2025503546 A JP 2025503546A
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cells
car
cell
hla
genetically modified
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JP2025503546A5 (enExample
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フリーズ，ジャン エグバート デ
グラツィア ロンカロロ，マリア
パリアード，ザビエル
フリーズ，デイビッド デ
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ティーアール１エックス，インコーポレーテッド
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
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    • C12N5/0602—Vertebrate cells
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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JP2024539566A 2021-12-30 2022-12-27 Ｉｌ－１０およびキメラ抗原受容体を発現するｃｄ４＋ｔ細胞およびその使用 Pending JP2025503546A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163295491P 2021-12-30 2021-12-30
US63/295,491 2021-12-30
PCT/US2022/082431 WO2023129929A1 (en) 2021-12-30 2022-12-27 Cd4+ t cells expressing il-10 and chimeric antigen receptors and uses thereof

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JP2025503546A true JP2025503546A (ja) 2025-02-04
JP2025503546A5 JP2025503546A5 (enExample) 2026-01-07

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US (2) US20250108113A1 (enExample)
EP (1) EP4456927A1 (enExample)
JP (1) JP2025503546A (enExample)
KR (1) KR20250005566A (enExample)
CN (1) CN119136843A (enExample)
AR (2) AR128124A1 (enExample)
AU (1) AU2022423984A1 (enExample)
CA (1) CA3244829A1 (enExample)
IL (1) IL313935A (enExample)
TW (1) TW202334400A (enExample)
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EP4678187A1 (en) * 2024-07-11 2026-01-14 Medizinische Hochschule Hannover Compound for use in the treatment of inflammatory bowel disease

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