JP2025503521A5 - - Google Patents

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Publication number
JP2025503521A5
JP2025503521A5 JP2024538726A JP2024538726A JP2025503521A5 JP 2025503521 A5 JP2025503521 A5 JP 2025503521A5 JP 2024538726 A JP2024538726 A JP 2024538726A JP 2024538726 A JP2024538726 A JP 2024538726A JP 2025503521 A5 JP2025503521 A5 JP 2025503521A5
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JP
Japan
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compound according
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unsubstituted
membered
substituted
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024538726A
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English (en)
Japanese (ja)
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JP2025503521A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/053976 external-priority patent/WO2023129512A1/en
Publication of JP2025503521A publication Critical patent/JP2025503521A/ja
Publication of JP2025503521A5 publication Critical patent/JP2025503521A5/ja
Pending legal-status Critical Current

Links

JP2024538726A 2021-12-31 2022-12-23 ニコチンアミドｎ－メチルトランスフェラーゼの二環式阻害剤、その組成物および使用 Pending JP2025503521A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163295657P 2021-12-31 2021-12-31
US63/295,657 2021-12-31
PCT/US2022/053976 WO2023129512A1 (en) 2021-12-31 2022-12-23 Bicyclic inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof

Publications (2)

Publication Number Publication Date
JP2025503521A JP2025503521A (ja) 2025-02-04
JP2025503521A5 true JP2025503521A5 (cg-RX-API-DMAC7.html) 2025-12-23

Family

ID=87000165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024538726A Pending JP2025503521A (ja) 2021-12-31 2022-12-23 ニコチンアミドｎ－メチルトランスフェラーゼの二環式阻害剤、その組成物および使用

Country Status (5)

Country Link
US (1) US20250368638A1 (cg-RX-API-DMAC7.html)
EP (1) EP4456892A4 (cg-RX-API-DMAC7.html)
JP (1) JP2025503521A (cg-RX-API-DMAC7.html)
CN (1) CN119110724A (cg-RX-API-DMAC7.html)
WO (1) WO2023129512A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021163683A1 (en) 2020-02-14 2021-08-19 President And Fellows Of Harvard College Inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof
WO2025129168A1 (en) * 2023-12-15 2025-06-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Triazolone inhibitors of nicotinamide n-methyltransferase and their therapeutic uses
TW202545926A (zh) 2024-01-12 2025-12-01 瑞典商阿斯特捷利康公司 作為菸鹼醯胺ｎ—甲基轉移酶抑制劑的哌啶衍生物
CN119143652B (zh) * 2024-09-13 2025-11-28 山东大学 一种手性2位双取代吲哚啉化合物及其合成方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201908293A (zh) * 2017-07-12 2019-03-01 美商必治妥美雅史谷比公司 作為rock抑制劑之5員及雙環雜環醯胺
WO2021163683A1 (en) * 2020-02-14 2021-08-19 President And Fellows Of Harvard College Inhibitors of nicotinamide n-methyltransferase, compositions and uses thereof

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