JP2025503493A5 - - Google Patents
Info
- Publication number
- JP2025503493A5 JP2025503493A5 JP2024538092A JP2024538092A JP2025503493A5 JP 2025503493 A5 JP2025503493 A5 JP 2025503493A5 JP 2024538092 A JP2024538092 A JP 2024538092A JP 2024538092 A JP2024538092 A JP 2024538092A JP 2025503493 A5 JP2025503493 A5 JP 2025503493A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- variable region
- chain variable
- cancer
- ror1 antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111623091 | 2021-12-28 | ||
| CN202111623091.0 | 2021-12-28 | ||
| CN202210230033 | 2022-03-10 | ||
| CN202210230033.X | 2022-03-10 | ||
| PCT/CN2022/142644 WO2023125619A1 (zh) | 2021-12-28 | 2022-12-28 | 抗ror1抗体和抗ror1抗体药物偶联物及其医药用途 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025503493A JP2025503493A (ja) | 2025-02-04 |
| JP2025503493A5 true JP2025503493A5 (https=) | 2026-01-13 |
Family
ID=86997955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024538092A Pending JP2025503493A (ja) | 2021-12-28 | 2022-12-28 | 抗ｒｏｒ１抗体と抗ｒｏｒ１抗体薬物複合体及びその医薬的使用 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250121081A1 (https=) |
| EP (1) | EP4458850A4 (https=) |
| JP (1) | JP2025503493A (https=) |
| KR (1) | KR20240125944A (https=) |
| CN (1) | CN118302448A (https=) |
| CA (1) | CA3242972A1 (https=) |
| TW (1) | TW202330619A (https=) |
| WO (1) | WO2023125619A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12144827B2 (en) | 2021-02-25 | 2024-11-19 | Lyell Immunopharma, Inc. | ROR1 targeting chimeric antigen receptor |
| CN118496347B (zh) * | 2024-05-30 | 2024-10-25 | 北京航空航天大学杭州创新研究院 | 一种用于抗体寡核苷酸偶联的方法 |
| WO2026077395A1 (zh) * | 2024-10-10 | 2026-04-16 | 杭州博之锐生物制药有限公司 | 抗ror1抗体药物-偶联物的联合用药 |
| WO2026077394A1 (zh) * | 2024-10-10 | 2026-04-16 | 杭州博之锐生物制药有限公司 | 一种抗ror1抗体-药物偶联物的药物组合物及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| US5208020A (en) | 1989-10-25 | 1993-05-04 | Immunogen Inc. | Cytotoxic agents comprising maytansinoids and their therapeutic use |
| EP1400536A1 (en) | 1991-06-14 | 2004-03-24 | Genentech Inc. | Method for making humanized antibodies |
| EP2478912B1 (en) | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| ES2818103T3 (es) * | 2015-01-16 | 2021-04-09 | Juno Therapeutics Inc | Anticuerpos y receptores de antígenos quiméricos específicos para ROR1 |
| US20200338210A1 (en) * | 2016-12-22 | 2020-10-29 | Ardeagen Corporation | Anti-ror1 antibody and conjugates thereof |
| AU2018289581C1 (en) | 2017-06-23 | 2025-01-30 | VelosBio Inc. | ROR1 antibody immunoconjugates |
| GB201710835D0 (en) * | 2017-07-05 | 2017-08-16 | Ucl Business Plc | ROR1 Antibodies |
| GB201710838D0 (en) * | 2017-07-05 | 2017-08-16 | Ucl Business Plc | Bispecific antibodies |
| GB201721802D0 (en) * | 2017-12-22 | 2018-02-07 | Almac Discovery Ltd | Ror1-specific antigen binding molecules |
| WO2020063676A1 (zh) | 2018-09-26 | 2020-04-02 | 江苏恒瑞医药股份有限公司 | 依喜替康类似物的配体-药物偶联物及其制备方法和应用 |
| CN114829402B (zh) * | 2019-09-27 | 2024-11-05 | 南京艾美斐生物医药科技有限公司 | 抗ror1抗体及其制备方法与应用 |
| WO2021115497A2 (zh) * | 2020-12-08 | 2021-06-17 | 和铂医药(上海)有限责任公司 | 蛋白-药物偶联物和定点偶联方法 |
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2022
- 2022-12-28 KR KR1020247023063A patent/KR20240125944A/ko active Pending
- 2022-12-28 EP EP22914871.3A patent/EP4458850A4/en active Pending
- 2022-12-28 US US18/724,604 patent/US20250121081A1/en active Pending
- 2022-12-28 CN CN202280078230.2A patent/CN118302448A/zh active Pending
- 2022-12-28 WO PCT/CN2022/142644 patent/WO2023125619A1/zh not_active Ceased
- 2022-12-28 CA CA3242972A patent/CA3242972A1/en active Pending
- 2022-12-28 TW TW111150439A patent/TW202330619A/zh unknown
- 2022-12-28 JP JP2024538092A patent/JP2025503493A/ja active Pending