JP2025501731A5 - - Google Patents
Info
- Publication number
- JP2025501731A5 JP2025501731A5 JP2024536420A JP2024536420A JP2025501731A5 JP 2025501731 A5 JP2025501731 A5 JP 2025501731A5 JP 2024536420 A JP2024536420 A JP 2024536420A JP 2024536420 A JP2024536420 A JP 2024536420A JP 2025501731 A5 JP2025501731 A5 JP 2025501731A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- optionally substituted
- therapeutic
- lnp
- lnp preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163291639P | 2021-12-20 | 2021-12-20 | |
| US63/291,639 | 2021-12-20 | ||
| US202263354627P | 2022-06-22 | 2022-06-22 | |
| US63/354,627 | 2022-06-22 | ||
| PCT/US2022/053209 WO2023121975A1 (en) | 2021-12-20 | 2022-12-16 | Ionizable amine lipids and lipid nanoparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025501731A JP2025501731A (ja) | 2025-01-23 |
| JP2025501731A5 true JP2025501731A5 (enExample) | 2025-12-23 |
Family
ID=85157159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024536420A Pending JP2025501731A (ja) | 2021-12-20 | 2022-12-16 | イオン化可能なアミン脂質及び脂質ナノ粒子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240335385A1 (enExample) |
| EP (1) | EP4452935A1 (enExample) |
| JP (1) | JP2025501731A (enExample) |
| AU (1) | AU2022418511A1 (enExample) |
| CA (1) | CA3241488A1 (enExample) |
| WO (1) | WO2023121975A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3145913A1 (en) | 2019-07-29 | 2021-02-04 | James Everett Dahlman | Nanomaterials containing constrained lipids and uses thereof |
| IL294318A (en) | 2020-01-09 | 2022-08-01 | Guide Therapeutics Llc | Nanomaterials |
| EP4281080A4 (en) | 2021-01-20 | 2025-09-24 | Beam Therapeutics Inc | NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT |
| CN116761888A (zh) | 2021-01-20 | 2023-09-15 | 比姆医疗股份有限公司 | 纳米材料 |
| US20260035338A1 (en) * | 2022-10-13 | 2026-02-05 | Shenzhen Shenxin Biotechnology Co., Ltd. | Amino lipid compound and lipid nanoparticle for delivering bioactive ingredient |
| TW202543585A (zh) | 2024-03-08 | 2025-11-16 | 美商健臻公司 | 脂質奈米粒子 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| WO2026030375A2 (en) | 2024-07-30 | 2026-02-05 | Genzyme Corporation | Lipid nanoparticles and methods of manufacture and use thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030083272A1 (en) | 1997-09-19 | 2003-05-01 | Lahive & Cockfield, Llp | Sense mrna therapy |
| CA2721333C (en) | 2008-04-15 | 2020-12-01 | Protiva Biotherapeutics, Inc. | Novel lipid formulations for nucleic acid delivery |
| KR20190039347A (ko) * | 2010-06-03 | 2019-04-10 | 알닐람 파마슈티칼스 인코포레이티드 | 활성제의 전달을 위한 생분해성 지질 |
| WO2013086354A1 (en) * | 2011-12-07 | 2013-06-13 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
| US20150165054A1 (en) | 2013-12-12 | 2015-06-18 | President And Fellows Of Harvard College | Methods for correcting caspase-9 point mutations |
| US10426737B2 (en) * | 2013-12-19 | 2019-10-01 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| JP6948313B6 (ja) | 2015-09-17 | 2022-01-14 | モデルナティエックス インコーポレイテッド | 治療剤の細胞内送達のための化合物および組成物 |
| IL310721B2 (en) | 2015-10-23 | 2025-11-01 | Harvard College | Nucleobase editors and uses thereof |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| TWI894123B (zh) * | 2017-12-27 | 2025-08-21 | 日商武田藥品工業有限公司 | 含核酸之脂質奈米粒子及其用途 |
| JP7693552B2 (ja) | 2019-02-13 | 2025-06-17 | ビーム セラピューティクス インク． | アデノシンデアミナーゼ塩基エディターおよびそれを用いて標的配列中の核酸塩基を改変する方法 |
| CN114127044A (zh) * | 2019-04-25 | 2022-03-01 | 英特利亚治疗股份有限公司 | 可电离的胺类脂质和脂质纳米颗粒 |
| WO2020246581A1 (ja) * | 2019-06-07 | 2020-12-10 | 富士フイルム株式会社 | 脂質組成物 |
-
2022
- 2022-12-16 CA CA3241488A patent/CA3241488A1/en active Pending
- 2022-12-16 WO PCT/US2022/053209 patent/WO2023121975A1/en not_active Ceased
- 2022-12-16 AU AU2022418511A patent/AU2022418511A1/en active Pending
- 2022-12-16 EP EP22851198.6A patent/EP4452935A1/en active Pending
- 2022-12-16 JP JP2024536420A patent/JP2025501731A/ja active Pending
-
2024
- 2024-06-18 US US18/746,810 patent/US20240335385A1/en active Pending
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