JP2024502954A5 - - Google Patents

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Publication number
JP2024502954A5
JP2024502954A5 JP2023539784A JP2023539784A JP2024502954A5 JP 2024502954 A5 JP2024502954 A5 JP 2024502954A5 JP 2023539784 A JP2023539784 A JP 2023539784A JP 2023539784 A JP2023539784 A JP 2023539784A JP 2024502954 A5 JP2024502954 A5 JP 2024502954A5
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JP
Japan
Prior art keywords
compound
optionally substituted
cells
independently
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023539784A
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English (en)
Japanese (ja)
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JP2024502954A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/012941 external-priority patent/WO2022159463A1/en
Publication of JP2024502954A publication Critical patent/JP2024502954A/ja
Publication of JP2024502954A5 publication Critical patent/JP2024502954A5/ja
Pending legal-status Critical Current

Links

JP2023539784A 2021-01-20 2022-01-19 ナノ材料 Pending JP2024502954A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163139734P 2021-01-20 2021-01-20
US63/139,734 2021-01-20
PCT/US2022/012941 WO2022159463A1 (en) 2021-01-20 2022-01-19 Nanomaterials

Publications (2)

Publication Number Publication Date
JP2024502954A JP2024502954A (ja) 2024-01-24
JP2024502954A5 true JP2024502954A5 (enExample) 2025-01-24

Family

ID=82549752

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023539784A Pending JP2024502954A (ja) 2021-01-20 2022-01-19 ナノ材料

Country Status (10)

Country Link
US (2) US12059477B2 (enExample)
EP (1) EP4281050A4 (enExample)
JP (1) JP2024502954A (enExample)
KR (1) KR20230131863A (enExample)
CN (1) CN116761888A (enExample)
AU (1) AU2022210313A1 (enExample)
CA (1) CA3203742A1 (enExample)
IL (1) IL303846A (enExample)
MX (1) MX2023008333A (enExample)
WO (1) WO2022159463A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3145913A1 (en) 2019-07-29 2021-02-04 James Everett Dahlman Nanomaterials containing constrained lipids and uses thereof
IL294318A (en) 2020-01-09 2022-08-01 Guide Therapeutics Llc Nanomaterials
EP4281080A4 (en) 2021-01-20 2025-09-24 Beam Therapeutics Inc NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT
CN116761888A (zh) 2021-01-20 2023-09-15 比姆医疗股份有限公司 纳米材料
JP2024503441A (ja) * 2021-01-20 2024-01-25 ビーム セラピューティクス インク. イオン化可能な脂質を含むナノ材料
CA3260437A1 (en) 2022-07-20 2024-01-25 Beam Therapeutics Inc. NANOMATERIALS INCLUDING TRIOLS
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110977A (en) 1990-02-14 1992-05-05 Eastman Kodak Company Ester-containing quaternary ammonium salts as adhesion improving toner charge agents
US20030083272A1 (en) 1997-09-19 2003-05-01 Lahive & Cockfield, Llp Sense mrna therapy
CA2721333C (en) 2008-04-15 2020-12-01 Protiva Biotherapeutics, Inc. Novel lipid formulations for nucleic acid delivery
PE20181541A1 (es) 2011-10-27 2018-09-26 Massachusetts Inst Technology Derivados de aminoacidos funcionalizados en la terminal n capaces de formar microesferas encapsuladoras de farmaco
CN107879960B (zh) 2013-03-08 2021-06-22 诺华股份有限公司 用于传递活性成分的脂质和脂质组合物
US20150165054A1 (en) 2013-12-12 2015-06-18 President And Fellows Of Harvard College Methods for correcting caspase-9 point mutations
US10426737B2 (en) 2013-12-19 2019-10-01 Novartis Ag Lipids and lipid compositions for the delivery of active agents
EP3083556B1 (en) 2013-12-19 2019-12-25 Novartis AG Lipids and lipid compositions for the delivery of active agents
US10125092B2 (en) 2014-09-05 2018-11-13 Novartis Ag Lipids and lipid compositions for the delivery of active agents
ES2880103T3 (es) * 2015-05-21 2021-11-23 Ohio State Innovation Foundation Derivados de benceno-1, 3, 5-tricarboxamida y usos de los mismos
JP6948313B6 (ja) 2015-09-17 2022-01-14 モデルナティエックス インコーポレイテッド 治療剤の細胞内送達のための化合物および組成物
IL310721B2 (en) 2015-10-23 2025-11-01 Harvard College Nucleobase editors and uses thereof
CN110214183A (zh) 2016-08-03 2019-09-06 哈佛大学的校长及成员们 腺苷核碱基编辑器及其用途
CN120682290A (zh) 2017-07-04 2025-09-23 尹图赛利有限公司 包含可裂解接头的化合物及其用途
CA3081414A1 (en) 2017-10-30 2019-05-09 Georgia Tech Research Corporation Multiplexed analysis of materials for tissue delivery
US11622942B2 (en) 2017-11-14 2023-04-11 Ohio State Innovation Foundation Benzene-1,3,5-tricarboxamide derived ester lipids and uses thereof
US20220009878A1 (en) 2018-10-02 2022-01-13 Intellia Therapeutics, Inc. Ionizable amine lipids
BR112021010853A2 (pt) * 2018-12-05 2021-08-31 Intellia Therapeutics, Inc. Lipídios de amina modificados
CN119700703A (zh) 2019-01-17 2025-03-28 佐治亚技术研究公司 含有氧化的胆固醇的药物递送系统
JP7693552B2 (ja) 2019-02-13 2025-06-17 ビーム セラピューティクス インク. アデノシンデアミナーゼ塩基エディターおよびそれを用いて標的配列中の核酸塩基を改変する方法
CN114127044A (zh) 2019-04-25 2022-03-01 英特利亚治疗股份有限公司 可电离的胺类脂质和脂质纳米颗粒
JP2022536112A (ja) 2019-06-05 2022-08-12 ガイド セラピューティクス,インコーポレーテッド 組織送達のための材料の分析
CA3145913A1 (en) 2019-07-29 2021-02-04 James Everett Dahlman Nanomaterials containing constrained lipids and uses thereof
WO2021021636A1 (en) 2019-07-29 2021-02-04 Georgia Tech Research Corporation Oligonucleotide antagonists for rna guided genome editing
KR20220113737A (ko) 2019-12-06 2022-08-16 가이드 테라퓨틱스 엘엘씨 나노물질
IL294318A (en) 2020-01-09 2022-08-01 Guide Therapeutics Llc Nanomaterials
EP4262819A4 (en) 2020-12-21 2024-12-04 Beam Therapeutics Inc. NANOMATERIALS WITH ESTER-BOUND ACETALS
EP4262818A4 (en) 2020-12-21 2025-03-26 Beam Therapeutics Inc. NANOMATERIALS WITH CARBONATES
JP2024503976A (ja) 2020-12-21 2024-01-30 ビーム セラピューティクス インク. アセタールを含むナノ材料
EP4281080A4 (en) 2021-01-20 2025-09-24 Beam Therapeutics Inc NANOMATERIALS COMPRISING A BIODEGRADABLE ELEMENT
CN116761888A (zh) 2021-01-20 2023-09-15 比姆医疗股份有限公司 纳米材料
JP2024503441A (ja) 2021-01-20 2024-01-25 ビーム セラピューティクス インク. イオン化可能な脂質を含むナノ材料
CA3203784A1 (en) 2021-01-20 2022-07-28 Beam Therapeutics Inc. Ionizable lipids for nanomaterials
EP4452925A1 (en) 2021-12-20 2024-10-30 Beam Therapeutics Inc. Nanomaterial comprising diamines
WO2023121970A1 (en) 2021-12-20 2023-06-29 Beam Therapeutics Inc. Ionizable amine and ester lipids and lipid nanoparticles
CA3241488A1 (en) 2021-12-20 2023-06-29 Beam Therapeutics Inc. Ionizable amine lipids and lipid nanoparticles
JP2025500824A (ja) 2021-12-20 2025-01-15 ビーム セラピューティクス インク. 四価脂質化合物を含むナノ材料
EP4452942A1 (en) 2021-12-20 2024-10-30 Beam Therapeutics Inc. Nanomaterials comprising disulfides

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