JP2025501324A - 脱毛の治療のための化合物 - Google Patents

脱毛の治療のための化合物 Download PDF

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Publication number
JP2025501324A
JP2025501324A JP2024540046A JP2024540046A JP2025501324A JP 2025501324 A JP2025501324 A JP 2025501324A JP 2024540046 A JP2024540046 A JP 2024540046A JP 2024540046 A JP2024540046 A JP 2024540046A JP 2025501324 A JP2025501324 A JP 2025501324A
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JP
Japan
Prior art keywords
alkyl
formula
compound
respect
hair growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2024540046A
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English (en)
Japanese (ja)
Other versions
JP2025501324A5 (enExample
Inventor
ルイ サン、ダニエル
ウォルター ジル、ダニエル
Original Assignee
ペリジ ファーマシューティカルズ インコーポレイテッド
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Publication of JP2025501324A publication Critical patent/JP2025501324A/ja
Publication of JP2025501324A5 publication Critical patent/JP2025501324A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2024540046A 2021-12-29 2022-12-29 脱毛の治療のための化合物 Pending JP2025501324A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163294769P 2021-12-29 2021-12-29
US63/294,769 2021-12-29
PCT/US2022/082555 WO2023130024A1 (en) 2021-12-29 2022-12-29 Compounds for treatment of hair loss

Publications (2)

Publication Number Publication Date
JP2025501324A true JP2025501324A (ja) 2025-01-17
JP2025501324A5 JP2025501324A5 (enExample) 2026-01-05

Family

ID=85199318

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024540046A Pending JP2025501324A (ja) 2021-12-29 2022-12-29 脱毛の治療のための化合物

Country Status (9)

Country Link
US (1) US20250145626A1 (enExample)
EP (1) EP4456984A1 (enExample)
JP (1) JP2025501324A (enExample)
KR (1) KR20240130763A (enExample)
CN (1) CN118843627A (enExample)
AU (1) AU2022424022A1 (enExample)
CA (1) CA3244826A1 (enExample)
IL (1) IL314012A (enExample)
WO (1) WO2023130024A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12649736B2 (en) 2019-12-20 2026-06-09 The Regents Of The University Of California Synthesis of compounds to promote hair growth
EP4172159A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
WO2026067664A1 (zh) * 2024-09-26 2026-04-02 海思科医药集团股份有限公司 一种氰基取代的杂环衍生物及其在医药上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL321754A (en) * 2017-06-30 2025-08-01 Univ California Compositions and methods for modulating hair growth
MX2021008089A (es) * 2019-01-02 2021-08-05 Univ California Composiciones y metodos para modular el crecimiento del cabello.
EP4172159A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
EP4172158A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth

Also Published As

Publication number Publication date
CN118843627A (zh) 2024-10-25
US20250145626A1 (en) 2025-05-08
CA3244826A1 (en) 2023-07-06
AU2022424022A1 (en) 2024-07-18
WO2023130024A1 (en) 2023-07-06
IL314012A (en) 2024-08-01
KR20240130763A (ko) 2024-08-29
EP4456984A1 (en) 2024-11-06

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