CA3244826A1 - COMPOUNDS FOR THE TREATMENT OF HAIR LOSS - Google Patents

COMPOUNDS FOR THE TREATMENT OF HAIR LOSS

Info

Publication number
CA3244826A1
CA3244826A1 CA3244826A CA3244826A CA3244826A1 CA 3244826 A1 CA3244826 A1 CA 3244826A1 CA 3244826 A CA3244826 A CA 3244826A CA 3244826 A CA3244826 A CA 3244826A CA 3244826 A1 CA3244826 A1 CA 3244826A1
Authority
CA
Canada
Prior art keywords
alkyl
formula
respect
compound
pct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3244826A
Other languages
English (en)
French (fr)
Inventor
Daniel Lui SUN
Daniel Walter GIL
Original Assignee
Pelage Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pelage Pharmaceuticals Inc filed Critical Pelage Pharmaceuticals Inc
Publication of CA3244826A1 publication Critical patent/CA3244826A1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3244826A 2021-12-29 2022-12-29 COMPOUNDS FOR THE TREATMENT OF HAIR LOSS Pending CA3244826A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163294769P 2021-12-29 2021-12-29
US63/294,769 2021-12-29
PCT/US2022/082555 WO2023130024A1 (en) 2021-12-29 2022-12-29 Compounds for treatment of hair loss

Publications (1)

Publication Number Publication Date
CA3244826A1 true CA3244826A1 (en) 2023-07-06

Family

ID=85199318

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3244826A Pending CA3244826A1 (en) 2021-12-29 2022-12-29 COMPOUNDS FOR THE TREATMENT OF HAIR LOSS

Country Status (9)

Country Link
US (1) US20250145626A1 (enExample)
EP (1) EP4456984A1 (enExample)
JP (1) JP2025501324A (enExample)
KR (1) KR20240130763A (enExample)
CN (1) CN118843627A (enExample)
AU (1) AU2022424022A1 (enExample)
CA (1) CA3244826A1 (enExample)
IL (1) IL314012A (enExample)
WO (1) WO2023130024A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12649736B2 (en) 2019-12-20 2026-06-09 The Regents Of The University Of California Synthesis of compounds to promote hair growth
EP4172159A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
WO2026067664A1 (zh) * 2024-09-26 2026-04-02 海思科医药集团股份有限公司 一种氰基取代的杂环衍生物及其在医药上的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL321754A (en) * 2017-06-30 2025-08-01 Univ California Compositions and methods for modulating hair growth
MX2021008089A (es) * 2019-01-02 2021-08-05 Univ California Composiciones y metodos para modular el crecimiento del cabello.
EP4172159A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth
EP4172158A4 (en) * 2020-06-30 2024-01-10 The Regents of the University of California Compositions and methods for modulating hair growth

Also Published As

Publication number Publication date
CN118843627A (zh) 2024-10-25
US20250145626A1 (en) 2025-05-08
AU2022424022A1 (en) 2024-07-18
WO2023130024A1 (en) 2023-07-06
JP2025501324A (ja) 2025-01-17
IL314012A (en) 2024-08-01
KR20240130763A (ko) 2024-08-29
EP4456984A1 (en) 2024-11-06

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