JP2025106309A5 - - Google Patents

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Publication number
JP2025106309A5
JP2025106309A5 JP2025046395A JP2025046395A JP2025106309A5 JP 2025106309 A5 JP2025106309 A5 JP 2025106309A5 JP 2025046395 A JP2025046395 A JP 2025046395A JP 2025046395 A JP2025046395 A JP 2025046395A JP 2025106309 A5 JP2025106309 A5 JP 2025106309A5
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JP
Japan
Prior art keywords
composition
car
subject
cells
antigen
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Pending
Application number
JP2025046395A
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English (en)
Japanese (ja)
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JP2025106309A (ja
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Priority claimed from JP2021563033A external-priority patent/JP2022529380A/ja
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Publication of JP2025106309A publication Critical patent/JP2025106309A/ja
Publication of JP2025106309A5 publication Critical patent/JP2025106309A5/ja
Pending legal-status Critical Current

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JP2025046395A 2019-04-26 2025-03-21 キメラ抗原受容体構築物およびcar-t細胞におけるそれらの使用 Pending JP2025106309A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962839175P 2019-04-26 2019-04-26
US62/839,175 2019-04-26
JP2021563033A JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびcar-t細胞におけるそれらの使用
PCT/US2020/029768 WO2020219843A1 (en) 2019-04-26 2020-04-24 Chimeric antigen receptor constructs and their use in car-t cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021563033A Division JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびcar-t細胞におけるそれらの使用

Publications (2)

Publication Number Publication Date
JP2025106309A JP2025106309A (ja) 2025-07-15
JP2025106309A5 true JP2025106309A5 (https=) 2025-10-27

Family

ID=72941305

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021563033A Pending JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびcar-t細胞におけるそれらの使用
JP2025046395A Pending JP2025106309A (ja) 2019-04-26 2025-03-21 キメラ抗原受容体構築物およびcar-t細胞におけるそれらの使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021563033A Pending JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびcar-t細胞におけるそれらの使用

Country Status (5)

Country Link
US (1) US12479890B2 (https=)
EP (1) EP3959236A4 (https=)
JP (2) JP2022529380A (https=)
CN (1) CN114269777A (https=)
WO (1) WO2020219843A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018050225A1 (en) * 2016-09-15 2018-03-22 Yu Di T-cell immunotherapy
TW202332765A (zh) * 2021-09-20 2023-08-16 美商英麥提克斯股份有限公司 用於t細胞療法之t細胞群體的單核球耗盡
KR20250097810A (ko) * 2022-09-13 2025-06-30 가부시키가이샤 사이토-팩토 이식을 위한 t 세포 및 이의 제조 방법
WO2024236547A1 (en) * 2023-05-18 2024-11-21 Inceptor Bio, Llc Modified phagocytic cells expressing chimeric antigen receptors comprising a herpes virus entry mediator (hvem) co-stimulatory domain and uses thereof
WO2026047626A1 (en) * 2024-08-30 2026-03-05 Inceptor Bio, Llc Compositions and methods involving immune cells engineered for binding bispecific antibodies for use in cell therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170241877A1 (en) * 2002-03-11 2017-08-24 Janusz B. Pawliszyn System and method for desorbing and detecting an analyte sorbed on a solid phase microextraction device
EP3074419B1 (en) * 2013-11-25 2018-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptors to control hiv infection
WO2015092024A2 (en) * 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
US20170335281A1 (en) 2014-03-15 2017-11-23 Novartis Ag Treatment of cancer using chimeric antigen receptor
JP6839074B2 (ja) * 2014-09-17 2021-03-03 ノバルティス アーゲー 養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング
IL297773B2 (en) 2014-11-17 2024-07-01 Adicet Bio Inc Engineered gamma delta t-cells
EP3233900A2 (en) * 2014-12-19 2017-10-25 Dana-Farber Cancer Institute, Inc. Chimeric antigen receptors and methods of use thereof
AU2016323985B2 (en) * 2015-09-17 2022-12-15 Novartis Ag CAR T cell therapies with enhanced efficacy
IL299616A (en) * 2016-01-08 2023-03-01 Univ California Conditionally active heterodimeric polypeptides and methods of using them
KR20180118175A (ko) * 2016-03-04 2018-10-30 노파르티스 아게 다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도
WO2017172952A1 (en) * 2016-04-01 2017-10-05 Promab Biotechnologies, Inc. Flag tagged cd19-car-t cells
EP3336107A1 (en) * 2016-12-15 2018-06-20 Miltenyi Biotec GmbH Immune cells expressing an antigen binding receptor and a chimeric costimulatory receptor
JP7280827B2 (ja) * 2017-01-18 2023-05-24 エクスマ バイオテック コーポレイション Axlまたはror2に対するキメラ抗原受容体およびその使用方法
CN110615842B (zh) * 2018-06-20 2023-05-09 上海隆耀生物科技有限公司 一种包含共刺激受体的嵌合抗原受体及应用

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