JP2025106309A5 - - Google Patents

Info

Publication number
JP2025106309A5
JP2025106309A5 JP2025046395A JP2025046395A JP2025106309A5 JP 2025106309 A5 JP2025106309 A5 JP 2025106309A5 JP 2025046395 A JP2025046395 A JP 2025046395A JP 2025046395 A JP2025046395 A JP 2025046395A JP 2025106309 A5 JP2025106309 A5 JP 2025106309A5
Authority
JP
Japan
Prior art keywords
composition
car
subject
cells
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025046395A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025106309A (ja
Filing date
Publication date
Priority claimed from JP2021563033A external-priority patent/JP2022529380A/ja
Application filed filed Critical
Publication of JP2025106309A publication Critical patent/JP2025106309A/ja
Publication of JP2025106309A5 publication Critical patent/JP2025106309A5/ja
Pending legal-status Critical Current

Links

JP2025046395A 2019-04-26 2025-03-21 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用 Pending JP2025106309A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962839175P 2019-04-26 2019-04-26
US62/839,175 2019-04-26
JP2021563033A JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用
PCT/US2020/029768 WO2020219843A1 (en) 2019-04-26 2020-04-24 Chimeric antigen receptor constructs and their use in car-t cells

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021563033A Division JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用

Publications (2)

Publication Number Publication Date
JP2025106309A JP2025106309A (ja) 2025-07-15
JP2025106309A5 true JP2025106309A5 (https=) 2025-10-27

Family

ID=72941305

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021563033A Pending JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用
JP2025046395A Pending JP2025106309A (ja) 2019-04-26 2025-03-21 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021563033A Pending JP2022529380A (ja) 2019-04-26 2020-04-24 キメラ抗原受容体構築物およびｃａｒ－ｔ細胞におけるそれらの使用

Country Status (5)

Country Link
US (1) US12479890B2 (https=)
EP (1) EP3959236A4 (https=)
JP (2) JP2022529380A (https=)
CN (1) CN114269777A (https=)
WO (1) WO2020219843A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110225760B (zh) * 2016-09-15 2023-11-07 埃里西拉医疗公司 T细胞免疫疗法
TW202332765A (zh) * 2021-09-20 2023-08-16 美商英麥提克斯股份有限公司 用於ｔ細胞療法之ｔ細胞群體的單核球耗盡
KR20250097810A (ko) * 2022-09-13 2025-06-30 가부시키가이샤 사이토-팩토 이식을 위한 t 세포 및 이의 제조 방법
WO2024236547A1 (en) * 2023-05-18 2024-11-21 Inceptor Bio, Llc Modified phagocytic cells expressing chimeric antigen receptors comprising a herpes virus entry mediator (hvem) co-stimulatory domain and uses thereof
WO2026047626A1 (en) * 2024-08-30 2026-03-05 Inceptor Bio, Llc Compositions and methods involving immune cells engineered for binding bispecific antibodies for use in cell therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170241877A1 (en) * 2002-03-11 2017-08-24 Janusz B. Pawliszyn System and method for desorbing and detecting an analyte sorbed on a solid phase microextraction device
US10246505B2 (en) * 2013-11-25 2019-04-02 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptors to control HIV infection
WO2015092024A2 (en) 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
EP3593812A3 (en) * 2014-03-15 2020-05-27 Novartis AG Treatment of cancer using chimeric antigen receptor
KR20250067191A (ko) * 2014-09-17 2025-05-14 노파르티스 아게 입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
WO2016081518A2 (en) 2014-11-17 2016-05-26 Adicet Bio, Inc. Engineered gamma delta t-cells
BR112017013176A2 (en) * 2014-12-19 2018-05-15 Dana-Farber Cancer Institute Inc. chimeric antigen receptors and methods for using them
US20180258149A1 (en) 2015-09-17 2018-09-13 Novartis Ag Car t cell therapies with enhanced efficacy
JP7068169B2 (ja) * 2016-01-08 2022-05-16 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 条件付活性ヘテロ二量体ポリペプチド及びその使用方法
AU2017225733A1 (en) 2016-03-04 2018-09-27 Novartis Ag Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore
WO2017172952A1 (en) * 2016-04-01 2017-10-05 Promab Biotechnologies, Inc. Flag tagged cd19-car-t cells
EP3336107A1 (en) * 2016-12-15 2018-06-20 Miltenyi Biotec GmbH Immune cells expressing an antigen binding receptor and a chimeric costimulatory receptor
SG10202107808SA (en) * 2017-01-18 2021-08-30 F1 Oncology Inc Chimeric antigen receptors against axl or ror2 and methods of use thereof
CN110615842B (zh) * 2018-06-20 2023-05-09 上海隆耀生物科技有限公司 一种包含共刺激受体的嵌合抗原受体及应用

Similar Documents

Publication Publication Date Title
JP2025106309A5 (https=)
EP4083073A1 (en) Novel chimeric antigen receptor and use thereof
JP7222600B2 (ja) 腫瘍細胞に特異的なキメラ抗原レセプター
US20250136697A1 (en) Methods and compositions comprising b7h3 chimeric antigen receptors
CN114401989A (zh) 靶向bcma的抗体及嵌合抗原受体
CN115232209A (zh) 靶向gprc5d的抗体及其用途
WO2022247795A1 (zh) 靶向Claudin18.2的纳米抗体及其用途
JP2018528786A5 (https=)
CN113717942A (zh) 一种联合嵌合抗原受体和i型干扰素的免疫治疗方法及其应用
CN110461881A (zh) 嵌合抗原受体
AU2023415250A1 (en) Antibody or antibody fragment targeting b7-h3, and use thereof in field of chimeric antigen receptor immune cell therapy
WO2023107593A2 (en) In vivo delivery to immune cells
WO2022148410A1 (zh) 抗pd-l1/抗4-1bb天然抗体结构样异源二聚体形式双特异抗体及其制备
JP2025513626A (ja) Ｃｉｉｔａ遺伝子がノックアウトされた操作された免疫細胞及びその用途
US20240299543A1 (en) Self-polarizing immune cells
CA3158047A1 (en) Bi-functional antibody against pd-l1 and tgf?
KR20250080888A (ko) 신규한 항메소텔린 키메라 항원 수용체 및 변형 면역 세포
US20230270858A1 (en) Novel co-stimulatory domain and use thereof
Battin et al. Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents
JPWO2020219843A5 (https=)
JPWO2021016585A5 (https=)
KR102393776B1 (ko) Cd22에 특이적인 인간화 항체 및 이를 이용한 키메라 항원 수용체
CN117430712A (zh) 靶向cxcr6的嵌合抗原受体及其用途
CN116600820A (zh) 嵌合抗原受体(car)间隔子修饰增强car t细胞功能
JPWO2022235662A5 (https=)