JP2025081323A5 - - Google Patents

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Publication number
JP2025081323A5
JP2025081323A5 JP2025009888A JP2025009888A JP2025081323A5 JP 2025081323 A5 JP2025081323 A5 JP 2025081323A5 JP 2025009888 A JP2025009888 A JP 2025009888A JP 2025009888 A JP2025009888 A JP 2025009888A JP 2025081323 A5 JP2025081323 A5 JP 2025081323A5
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JP
Japan
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drawings
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025009888A
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English (en)
Japanese (ja)
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JP2025081323A (ja
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Publication date
Priority claimed from PCT/US2020/014819 external-priority patent/WO2020154520A1/en
Application filed filed Critical
Publication of JP2025081323A publication Critical patent/JP2025081323A/ja
Publication of JP2025081323A5 publication Critical patent/JP2025081323A5/ja
Pending legal-status Critical Current

Links

JP2025009888A 2019-01-23 2025-01-23 ホスホジエステラーゼ4(pde4)阻害によるてんかんの治療方法 Pending JP2025081323A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962796002P 2019-01-23 2019-01-23
US62/796,002 2019-01-23
PCT/US2020/014819 WO2020154520A1 (en) 2019-01-23 2020-01-23 Methods of treating epilepsy via phosphodiesterase 4 (pde4) inhibition
JP2021543315A JP2022518292A (ja) 2019-01-23 2020-01-23 ホスホジエステラーゼ4(pde4)阻害によるてんかんの治療方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021543315A Division JP2022518292A (ja) 2019-01-23 2020-01-23 ホスホジエステラーゼ4(pde4)阻害によるてんかんの治療方法

Publications (2)

Publication Number Publication Date
JP2025081323A JP2025081323A (ja) 2025-05-27
JP2025081323A5 true JP2025081323A5 (https=) 2026-01-20

Family

ID=71735544

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021543315A Pending JP2022518292A (ja) 2019-01-23 2020-01-23 ホスホジエステラーゼ4(pde4)阻害によるてんかんの治療方法
JP2025009888A Pending JP2025081323A (ja) 2019-01-23 2025-01-23 ホスホジエステラーゼ4(pde4)阻害によるてんかんの治療方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021543315A Pending JP2022518292A (ja) 2019-01-23 2020-01-23 ホスホジエステラーゼ4(pde4)阻害によるてんかんの治療方法

Country Status (6)

Country Link
US (1) US20220098257A1 (https=)
EP (1) EP3914701B1 (https=)
JP (2) JP2022518292A (https=)
CN (1) CN113490739A (https=)
CA (1) CA3127357A1 (https=)
WO (1) WO2020154520A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201911603D0 (en) * 2019-08-14 2019-09-25 Healx Ltd Treatment
EP4001923B1 (en) 2020-11-23 2024-06-05 Roche Diagnostics GmbH Laboratory sample distribution system and laboratory automation system
EP4249607A1 (en) * 2022-03-21 2023-09-27 Warszawski Uniwersytet Medyczny Panel of markers for prediction of epilepsy recurrence in patients with tuberous sclerosis and the uses thereof
CN121022847B (zh) * 2025-10-31 2026-02-06 温州医科大学附属眼视光医院 一种敲除斑马鱼pde6a的sgRNA及其在视觉疾病中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1414841B1 (en) * 2001-07-10 2012-11-14 Lakewood-Amedex, Inc Oligonucleotide-containing pharmacological compositions and their use
US20050164275A1 (en) * 2002-10-18 2005-07-28 Incyte Corporation Phosphodiesterases
WO2006050057A2 (en) * 2004-10-28 2006-05-11 Celgene Corporation Methods and compositions using pde4 modulators for treatment and management of central nervous system injury
JP2009509984A (ja) * 2005-09-29 2009-03-12 バイエル・ヘルスケア・アクチェンゲゼルシャフト 泌尿器系障害の処置用のpde阻害剤およびそれらの組合せ
CA2657093A1 (en) * 2006-07-07 2008-01-10 Steven P. Govek Bicyclic heteroaryl inhibitors of pde4
EP2334180A4 (en) * 2008-09-15 2013-07-03 Univ California RESTRICTING DISEASES WITH A COMBINATION OF ACTIVE SUBSTANCES TO INCREASE THE CONCENTRATION OF EPOXYGENATED FATTY ACIDS AND ACTIVE SUBSTANCES TO INCREASE THE CAMP CONCENTRATION
US20130065936A1 (en) * 2010-05-14 2013-03-14 The Regents Of The University Of California Modulation of bioactive epoxy-fatty acid levels by phosphodiesterase inhibitors
US20130252924A1 (en) * 2010-11-11 2013-09-26 Akron Molecules Gmbh Compounds and Methods for Treating Pain
US8865723B2 (en) * 2012-10-25 2014-10-21 Tetra Discovery Partners Llc Selective PDE4 B inhibition and improvement in cognition in subjects with brain injury
WO2014083099A1 (en) * 2012-11-30 2014-06-05 Leo Pharma A/S A method of inhibiting the expression of il-22 in activated t-cells
CN107787322B (zh) * 2015-06-17 2023-07-07 辉瑞大药厂 三环化合物以及它们作为磷酸二酯酶抑制剂的用途
CN113332292A (zh) * 2016-02-23 2021-09-03 辉瑞公司 6,7-二氢-5H-吡唑并[5,1-b][1,3]噁嗪-2-甲酰胺化合物

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