JP2025023916A5 - - Google Patents
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- Publication number
- JP2025023916A5 JP2025023916A5 JP2024178540A JP2024178540A JP2025023916A5 JP 2025023916 A5 JP2025023916 A5 JP 2025023916A5 JP 2024178540 A JP2024178540 A JP 2024178540A JP 2024178540 A JP2024178540 A JP 2024178540A JP 2025023916 A5 JP2025023916 A5 JP 2025023916A5
- Authority
- JP
- Japan
- Prior art keywords
- rna molecule
- pharmaceutical composition
- secretion
- immunostimulatory
- nucleotides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 230000003308 immunostimulating effect Effects 0.000 claims 8
- 230000028327 secretion Effects 0.000 claims 6
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 102000006992 Interferon-alpha Human genes 0.000 claims 3
- 108010047761 Interferon-alpha Proteins 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 230000001939 inductive effect Effects 0.000 claims 3
- 108060008682 Tumor Necrosis Factor Proteins 0.000 claims 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 claims 2
- 229940044616 toll-like receptor 7 agonist Drugs 0.000 claims 2
- 102000008070 Interferon-gamma Human genes 0.000 claims 1
- 108010074328 Interferon-gamma Proteins 0.000 claims 1
- 102000003814 Interleukin-10 Human genes 0.000 claims 1
- 108090000174 Interleukin-10 Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 210000003719 b-lymphocyte Anatomy 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 230000036755 cellular response Effects 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 230000002538 fungal effect Effects 0.000 claims 1
- 229960003130 interferon gamma Drugs 0.000 claims 1
- 229940076144 interleukin-10 Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 230000003071 parasitic effect Effects 0.000 claims 1
- 210000005134 plasmacytoid dendritic cell Anatomy 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2017057094 | 2017-03-24 | ||
| EPPCT/EP2017/057094 | 2017-03-24 | ||
| PCT/EP2018/057206 WO2018172426A1 (en) | 2017-03-24 | 2018-03-21 | Methods and compositions for stimulating immune response |
| JP2019551991A JP7651261B2 (ja) | 2017-03-24 | 2018-03-21 | 免疫応答を刺激するための方法及び組成物 |
| JP2022193597A JP2023036615A (ja) | 2017-03-24 | 2022-12-02 | 免疫応答を刺激するための方法及び組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022193597A Division JP2023036615A (ja) | 2017-03-24 | 2022-12-02 | 免疫応答を刺激するための方法及び組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025023916A JP2025023916A (ja) | 2025-02-19 |
| JP2025023916A5 true JP2025023916A5 (https=) | 2025-03-03 |
Family
ID=61911533
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019551991A Active JP7651261B2 (ja) | 2017-03-24 | 2018-03-21 | 免疫応答を刺激するための方法及び組成物 |
| JP2022193597A Pending JP2023036615A (ja) | 2017-03-24 | 2022-12-02 | 免疫応答を刺激するための方法及び組成物 |
| JP2024178540A Pending JP2025023916A (ja) | 2017-03-24 | 2024-10-11 | 免疫応答を刺激するための方法及び組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019551991A Active JP7651261B2 (ja) | 2017-03-24 | 2018-03-21 | 免疫応答を刺激するための方法及び組成物 |
| JP2022193597A Pending JP2023036615A (ja) | 2017-03-24 | 2022-12-02 | 免疫応答を刺激するための方法及び組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11471522B2 (https=) |
| EP (2) | EP3600389B1 (https=) |
| JP (3) | JP7651261B2 (https=) |
| AU (1) | AU2018240421B2 (https=) |
| CA (1) | CA3056819A1 (https=) |
| ES (1) | ES2951684T3 (https=) |
| WO (1) | WO2018172426A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2951684T3 (es) | 2017-03-24 | 2023-10-24 | BioNTech SE | Métodos y composiciones para estimular la respuesta inmune |
| US12194157B2 (en) | 2020-04-09 | 2025-01-14 | Finncure Oy | Carrier for targeted delivery to a host |
| FI20215508A1 (en) | 2020-04-09 | 2021-10-10 | Niemelae Erik Johan | Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection |
| WO2022099003A1 (en) * | 2020-11-06 | 2022-05-12 | Sanofi | Lipid nanoparticles for delivering mrna vaccines |
| CN114733455B (zh) * | 2022-04-15 | 2023-02-14 | 北京田园奥瑞生物科技有限公司 | 一种利用生物改性β-环糊精纳米磁颗粒进行快速哺乳动物精子分型的方法 |
| WO2025144938A1 (en) | 2023-12-26 | 2025-07-03 | Emmune, Inc. | Systems for nucleic acid transfer |
| WO2025223684A1 (en) | 2024-04-23 | 2025-10-30 | BioNTech SE | Methods and compositions for stimulating immune response |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007526253A (ja) * | 2004-02-19 | 2007-09-13 | コーリー ファーマシューティカル グループ，インコーポレイテッド | 免疫刺激性ウイルスｒｎａオリゴヌクレオチド |
| EP2167662A2 (en) * | 2007-05-14 | 2010-03-31 | Technische Universität München | Pharmaceutical compounds comprising abasic oligonucleotides |
| EP3263707A1 (en) * | 2009-03-17 | 2018-01-03 | Rheinische Friedrich-Wilhelms-Universität Bonn | Tlr8 ligand and uses thereof |
| US8840902B2 (en) * | 2010-03-16 | 2014-09-23 | Biontech Ag | Tumor vaccination involving a humoral immune response against self-proteins |
| WO2013126963A1 (en) * | 2012-02-29 | 2013-09-06 | Benitec Biopharma Limited | Pain treatment |
| WO2016179034A2 (en) | 2015-05-01 | 2016-11-10 | The Trustees Of The University Of Pennsylvania | Methods and compositions for stimulating immune response using potent immunostimulatory rna motifs |
| JP7384512B2 (ja) | 2015-10-22 | 2023-11-21 | モデルナティエックス インコーポレイテッド | 広域インフルエンザウイルスワクチン |
| ES2951684T3 (es) | 2017-03-24 | 2023-10-24 | BioNTech SE | Métodos y composiciones para estimular la respuesta inmune |
-
2018
- 2018-03-21 ES ES18716138T patent/ES2951684T3/es active Active
- 2018-03-21 EP EP18716138.5A patent/EP3600389B1/en active Active
- 2018-03-21 WO PCT/EP2018/057206 patent/WO2018172426A1/en not_active Ceased
- 2018-03-21 CA CA3056819A patent/CA3056819A1/en active Pending
- 2018-03-21 AU AU2018240421A patent/AU2018240421B2/en active Active
- 2018-03-21 US US16/496,858 patent/US11471522B2/en active Active
- 2018-03-21 EP EP23172071.5A patent/EP4241786A3/en active Pending
- 2018-03-21 JP JP2019551991A patent/JP7651261B2/ja active Active
-
2022
- 2022-09-12 US US17/931,215 patent/US12168051B2/en active Active
- 2022-12-02 JP JP2022193597A patent/JP2023036615A/ja active Pending
-
2024
- 2024-10-11 JP JP2024178540A patent/JP2025023916A/ja active Pending
- 2024-11-13 US US18/946,351 patent/US20260115272A1/en active Pending
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