JP2024546431A5 - - Google Patents
Info
- Publication number
- JP2024546431A5 JP2024546431A5 JP2024527671A JP2024527671A JP2024546431A5 JP 2024546431 A5 JP2024546431 A5 JP 2024546431A5 JP 2024527671 A JP2024527671 A JP 2024527671A JP 2024527671 A JP2024527671 A JP 2024527671A JP 2024546431 A5 JP2024546431 A5 JP 2024546431A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- pharmaceutically acceptable
- acceptable salt
- independently
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163278242P | 2021-11-11 | 2021-11-11 | |
| US63/278,242 | 2021-11-11 | ||
| PCT/US2022/049607 WO2023086514A1 (en) | 2021-11-11 | 2022-11-10 | Ionizable cationic lipids for rna delivery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024546431A JP2024546431A (ja) | 2024-12-24 |
| JP2024546431A5 true JP2024546431A5 (https=) | 2025-12-03 |
Family
ID=86336481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024527671A Pending JP2024546431A (ja) | 2021-11-11 | 2022-11-10 | Ｒｎａ送達のためのイオン化可能なカチオン性脂質 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20230295081A1 (https=) |
| EP (1) | EP4430026A4 (https=) |
| JP (1) | JP2024546431A (https=) |
| KR (1) | KR20240128677A (https=) |
| CN (1) | CN118451059A (https=) |
| AR (1) | AR127659A1 (https=) |
| AU (1) | AU2022387111A1 (https=) |
| CA (1) | CA3237904A1 (https=) |
| IL (1) | IL312732A (https=) |
| MX (1) | MX2024005714A (https=) |
| TW (1) | TW202337498A (https=) |
| UY (1) | UY40016A (https=) |
| WO (1) | WO2023086514A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10383952B2 (en) | 2016-12-21 | 2019-08-20 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| CN116574070B (zh) * | 2023-04-07 | 2025-10-31 | 华南理工大学 | 一种多尾型可电离脂质及其制备方法与应用 |
| KR20260008111A (ko) * | 2023-05-10 | 2026-01-15 | 아크투루스 쎄라퓨틱스, 인크. | Rna 전달을 위한 이온화 가능한 양이온성 지질 |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2024253473A1 (ko) * | 2023-06-07 | 2024-12-12 | 포항공과대학교 산학협력단 | 핵산 치료제에 사용되는 기능성 지질 라이브러리를 합성하기 위한 단일 연속 유동 합성 방법 |
| WO2025076113A1 (en) * | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| US20250332281A2 (en) | 2023-12-15 | 2025-10-30 | Capstan Therapeutics, Inc. | Humanized anti-cd8 antibodies and uses thereof |
| WO2025166325A1 (en) | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025213138A1 (en) | 2024-04-05 | 2025-10-09 | Editas Medicine, Inc. | Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014089239A1 (en) * | 2012-12-07 | 2014-06-12 | Alnylam Pharmaceuticals, Inc. | Improved nucleic acid lipid particle formulations |
| US9834510B2 (en) * | 2015-12-30 | 2017-12-05 | Arcturus Therapeutics, Inc. | Aromatic ionizable cationic lipid |
| US10526284B2 (en) * | 2016-12-21 | 2020-01-07 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| SG11202110036RA (en) * | 2019-03-19 | 2021-10-28 | Arcturus Therapeutics Inc | Method of making lipid-encapsulated rna nanoparticles |
| JP7562995B2 (ja) * | 2020-06-10 | 2024-10-08 | 大日本印刷株式会社 | 重合性液晶組成物、重合体、位相差フィルム及びその製造方法、転写用積層体、光学部材及びその製造方法、並びに表示装置 |
-
2022
- 2022-11-10 WO PCT/US2022/049607 patent/WO2023086514A1/en not_active Ceased
- 2022-11-10 JP JP2024527671A patent/JP2024546431A/ja active Pending
- 2022-11-10 CA CA3237904A patent/CA3237904A1/en active Pending
- 2022-11-10 EP EP22893632.4A patent/EP4430026A4/en active Pending
- 2022-11-10 CN CN202280086428.5A patent/CN118451059A/zh active Pending
- 2022-11-10 US US17/985,045 patent/US20230295081A1/en active Pending
- 2022-11-10 KR KR1020247019290A patent/KR20240128677A/ko active Pending
- 2022-11-10 AU AU2022387111A patent/AU2022387111A1/en active Pending
- 2022-11-10 IL IL312732A patent/IL312732A/en unknown
- 2022-11-10 TW TW111143004A patent/TW202337498A/zh unknown
- 2022-11-10 MX MX2024005714A patent/MX2024005714A/es unknown
- 2022-11-11 AR ARP220103119A patent/AR127659A1/es unknown
- 2022-11-11 UY UY0001040016A patent/UY40016A/es unknown
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