JP2024518375A5 - - Google Patents
Info
- Publication number
- JP2024518375A5 JP2024518375A5 JP2023567891A JP2023567891A JP2024518375A5 JP 2024518375 A5 JP2024518375 A5 JP 2024518375A5 JP 2023567891 A JP2023567891 A JP 2023567891A JP 2023567891 A JP2023567891 A JP 2023567891A JP 2024518375 A5 JP2024518375 A5 JP 2024518375A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- lipid
- acceptable salt
- compound
- lipid composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163185303P | 2021-05-06 | 2021-05-06 | |
| US63/185,303 | 2021-05-06 | ||
| PCT/US2022/027874 WO2022235935A2 (en) | 2021-05-06 | 2022-05-05 | Ionizable cationic lipids for rna delivery |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024518375A JP2024518375A (ja) | 2024-05-01 |
| JP2024518375A5 true JP2024518375A5 (https=) | 2025-05-13 |
Family
ID=83932495
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023567891A Pending JP2024518375A (ja) | 2021-05-06 | 2022-05-05 | Ｒｎａ送達のためのイオン化可能なカチオン性脂質 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220389422A1 (https=) |
| EP (1) | EP4352038A4 (https=) |
| JP (1) | JP2024518375A (https=) |
| KR (1) | KR20240008872A (https=) |
| CN (2) | CN121517316A (https=) |
| AU (1) | AU2022268975A1 (https=) |
| CA (1) | CA3219192A1 (https=) |
| TW (1) | TW202313557A (https=) |
| WO (1) | WO2022235935A2 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10383952B2 (en) | 2016-12-21 | 2019-08-20 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| WO2022115645A1 (en) | 2020-11-25 | 2022-06-02 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids, and related methods of use |
| CA3271445A1 (en) * | 2022-11-16 | 2024-05-23 | Seawolf Therapeutics, Inc. | IONIZABLE LIPIDS AND LIPID NANOPARTICLE COMPOSITIONS FOR NUCLEIC ACID ADMINISTRATION |
| EP4683905A1 (en) * | 2023-03-22 | 2026-01-28 | Nanovation Therapeutics Inc. | Ionizable anionic lipids |
| KR20260008111A (ko) * | 2023-05-10 | 2026-01-15 | 아크투루스 쎄라퓨틱스, 인크. | Rna 전달을 위한 이온화 가능한 양이온성 지질 |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| CN117482066B (zh) * | 2023-11-02 | 2024-08-13 | 深圳市易瑞生物技术股份有限公司 | 脂质组合物和用于脂质组合物的化合物 |
| WO2025117732A1 (en) * | 2023-11-29 | 2025-06-05 | Akagera Medicines, Inc. | Lipid nanoparticles for delivery of nucleic acids and methods of use thereof |
| US20250332281A2 (en) | 2023-12-15 | 2025-10-30 | Capstan Therapeutics, Inc. | Humanized anti-cd8 antibodies and uses thereof |
| WO2025134071A1 (en) * | 2023-12-22 | 2025-06-26 | Sanofi | Malic and glutaric acid based ionizable lipids |
| WO2025140421A1 (zh) * | 2023-12-29 | 2025-07-03 | 北京剂泰医药科技有限公司 | 可电离脂质化合物及其在递送核酸疫苗中的用途 |
| CN117820149B (zh) * | 2023-12-29 | 2025-01-07 | 北京剂泰医药科技有限公司 | 可电离脂质化合物 |
| WO2025166325A1 (en) | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025213138A1 (en) | 2024-04-05 | 2025-10-09 | Editas Medicine, Inc. | Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| CN121021427A (zh) * | 2024-07-30 | 2025-11-28 | 广州市恒诺康医药科技有限公司 | 可离子化脂质及其用途 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110305769A1 (en) * | 2008-11-17 | 2011-12-15 | Enzon Pharmaceuticals, Inc. | Branched cationic lipids for nucleic acids delivery system |
| EP3485875A1 (en) * | 2011-11-04 | 2019-05-22 | Nitto Denko Corporation | Single use system for sterelily producing lipid-nucleic acid particles |
| US9579338B2 (en) * | 2011-11-04 | 2017-02-28 | Nitto Denko Corporation | Method of producing lipid nanoparticles for drug delivery |
| WO2013086354A1 (en) * | 2011-12-07 | 2013-06-13 | Alnylam Pharmaceuticals, Inc. | Biodegradable lipids for the delivery of active agents |
| AU2012347605B2 (en) * | 2011-12-07 | 2017-09-21 | Alnylam Pharmaceuticals, Inc. | Branched alkyl and cycloalkyl terminated biodegradable lipids for the delivery of active agents |
| WO2014089239A1 (en) * | 2012-12-07 | 2014-06-12 | Alnylam Pharmaceuticals, Inc. | Improved nucleic acid lipid particle formulations |
| JP6620093B2 (ja) * | 2013-07-23 | 2019-12-11 | アービュートゥス バイオファーマ コーポレイションＡｒｂｕｔｕｓ Ｂｉｏｐｈａｒｍａ Ｃｏｒｐｏｒａｔｉｏｎ | メッセンジャーｒｎａを送達するための組成物及び方法 |
| US10383952B2 (en) * | 2016-12-21 | 2019-08-20 | Arcturus Therapeutics, Inc. | Ionizable cationic lipid for RNA delivery |
| EP3842538A4 (en) * | 2018-08-10 | 2022-06-08 | Kyoto University | METHOD OF TRANSFECTION INTO CARDIOMYOCYTES USING CATIONIC LIPID |
| PT3908568T (pt) * | 2019-01-11 | 2024-09-30 | Acuitas Therapeutics Inc | Lípidos para a administração de agentes ativos por nanopartículas lipídicas |
| SG11202110036RA (en) * | 2019-03-19 | 2021-10-28 | Arcturus Therapeutics Inc | Method of making lipid-encapsulated rna nanoparticles |
| CN114901253A (zh) * | 2019-08-14 | 2022-08-12 | 爱康泰生治疗公司 | 用于递送核酸的改进的脂质纳米颗粒 |
-
2022
- 2022-05-05 KR KR1020237041979A patent/KR20240008872A/ko active Pending
- 2022-05-05 US US17/737,690 patent/US20220389422A1/en active Pending
- 2022-05-05 TW TW111116949A patent/TW202313557A/zh unknown
- 2022-05-05 AU AU2022268975A patent/AU2022268975A1/en active Pending
- 2022-05-05 JP JP2023567891A patent/JP2024518375A/ja active Pending
- 2022-05-05 CN CN202511412284.XA patent/CN121517316A/zh active Pending
- 2022-05-05 CN CN202280043621.0A patent/CN117715886B/zh active Active
- 2022-05-05 CA CA3219192A patent/CA3219192A1/en active Pending
- 2022-05-05 EP EP22799597.4A patent/EP4352038A4/en active Pending
- 2022-05-05 WO PCT/US2022/027874 patent/WO2022235935A2/en not_active Ceased
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