JP2024543954A - Nant covidワクチン交差反応性 - Google Patents

Nant covidワクチン交差反応性 Download PDF

Info

Publication number
JP2024543954A
JP2024543954A JP2024532354A JP2024532354A JP2024543954A JP 2024543954 A JP2024543954 A JP 2024543954A JP 2024532354 A JP2024532354 A JP 2024532354A JP 2024532354 A JP2024532354 A JP 2024532354A JP 2024543954 A JP2024543954 A JP 2024543954A
Authority
JP
Japan
Prior art keywords
sars
recombinant
protein
seq
vaccine composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024532354A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024543954A5 (https=
Inventor
パトリック、スン-シオン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunitybio Inc
Original Assignee
Immunitybio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunitybio Inc filed Critical Immunitybio Inc
Publication of JP2024543954A publication Critical patent/JP2024543954A/ja
Publication of JP2024543954A5 publication Critical patent/JP2024543954A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/215Coronaviridae, e.g. avian infectious bronchitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/20011Coronaviridae
    • C12N2770/20034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2024532354A 2021-11-30 2022-11-29 Nant covidワクチン交差反応性 Pending JP2024543954A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163284203P 2021-11-30 2021-11-30
US63/284,203 2021-11-30
PCT/US2022/080561 WO2023102375A1 (en) 2021-11-30 2022-11-29 Nant covid vaccine cross reactivity

Publications (2)

Publication Number Publication Date
JP2024543954A true JP2024543954A (ja) 2024-11-26
JP2024543954A5 JP2024543954A5 (https=) 2025-06-09

Family

ID=86613140

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024532354A Pending JP2024543954A (ja) 2021-11-30 2022-11-29 Nant covidワクチン交差反応性

Country Status (8)

Country Link
US (4) US11911459B2 (https=)
EP (1) EP4440614A4 (https=)
JP (1) JP2024543954A (https=)
KR (1) KR20240113521A (https=)
CN (1) CN118338912A (https=)
AU (1) AU2022400924A1 (https=)
CA (1) CA3236215A1 (https=)
WO (1) WO2023102375A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7692925B2 (ja) * 2020-03-11 2025-06-16 ナントセル,インコーポレイテッド Covid-19の治療及びその方法
EP4118225A1 (en) * 2020-03-13 2023-01-18 The Johns Hopkins University Exosomal nucleic acid vaccine modularly configured to harness multiple antigen presentation mechanisms
CN115666634A (zh) * 2020-03-27 2023-01-31 瑞典疫苗制药有限公司 用于治疗和预防冠状病毒的组合物和方法
WO2021255270A1 (en) * 2020-06-19 2021-12-23 Ziphius Vaccines Self-amplifying sars-cov-2 rna vaccine

Also Published As

Publication number Publication date
US12016916B2 (en) 2024-06-25
EP4440614A1 (en) 2024-10-09
CA3236215A1 (en) 2023-06-08
US11911459B2 (en) 2024-02-27
KR20240113521A (ko) 2024-07-22
US20240424088A1 (en) 2024-12-26
WO2023102375A1 (en) 2023-06-08
US20230190921A1 (en) 2023-06-22
EP4440614A4 (en) 2025-12-17
US20240226282A1 (en) 2024-07-11
US12168052B2 (en) 2024-12-17
CN118338912A (zh) 2024-07-12
AU2022400924A1 (en) 2024-05-02
US20240108717A1 (en) 2024-04-04

Similar Documents

Publication Publication Date Title
KR20220154121A (ko) 코로나바이러스 면역원성 조성물 및 이의 용도
EA012037B1 (ru) Поливалентные вакцины, содержащие рекомбинантные вирусные векторы
WO2022003119A1 (en) Cross-reactive coronavirus vaccine
WO2022090679A1 (en) Coronavirus polypeptide
JP6917303B2 (ja) 人工多抗原融合タンパク質およびその製造と使用
WO2023023940A1 (zh) 一种诱导广谱抗冠状病毒的t细胞疫苗免疫原及其应用
Ouaked et al. Non-clinical evaluation of local and systemic immunity induced by different vaccination strategies of the candidate tuberculosis vaccine M72/AS01
WO2023160654A1 (zh) 一种可诱导广谱中和活性重组多组分新冠病毒三聚体蛋白疫苗的制备及应用
KR101845571B1 (ko) 전통적 돼지열에 대한 마커 백신
US20230192777A1 (en) Epitopic vaccine for african swine fever virus
US12168052B2 (en) Nant COVID vaccine cross reactivity
WO2025189435A1 (zh) 针对猫fipv的多表位抗原构建rna疫苗的方法
CN110382518B (zh) 用于血清型a型口蹄疫病毒的嵌合疫苗
EP4341275A1 (en) Amino acids, nucleotides and vectors expressing the same and uses thereof in preventing sarbecovirus infection
US20260053900A1 (en) Use of virus-like particles in vaccination
US20250332246A1 (en) Enhanced expression via autotransporters
US20240092840A1 (en) Vaccine formulation comprising recombinant overlapping peptides and native proteins
US20220023412A1 (en) Compositions Useful in Both Homologous And Heterologous Vaccine Regimens
CN117801119A (zh) T细胞表位疫苗及其设计方法
WO2024152845A1 (zh) 抗SARS-CoV-2或突变体mRNA疫苗和重组蛋白亚单位疫苗制备及应用
AU2024333842A1 (en) T cell broad betacoronavirus vaccine
WO2025189436A1 (zh) 针对猫fipv的多表位抗原构建环状rna疫苗的方法
Pardieck et al. an der, Gracht, ETI an der, Veerkamp, DMB, Behr, F

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250529

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250529