JP2024543512A5 - - Google Patents
Info
- Publication number
- JP2024543512A5 JP2024543512A5 JP2024529158A JP2024529158A JP2024543512A5 JP 2024543512 A5 JP2024543512 A5 JP 2024543512A5 JP 2024529158 A JP2024529158 A JP 2024529158A JP 2024529158 A JP2024529158 A JP 2024529158A JP 2024543512 A5 JP2024543512 A5 JP 2024543512A5
- Authority
- JP
- Japan
- Prior art keywords
- caution
- pharmaceutically acceptable
- alkyl
- acceptable salt
- compound according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2021/130956 | 2021-11-16 | ||
| CN2021130956 | 2021-11-16 | ||
| CN2022079709 | 2022-03-08 | ||
| CNPCT/CN2022/079709 | 2022-03-08 | ||
| CNPCT/CN2022/126722 | 2022-10-21 | ||
| CN2022126722 | 2022-10-21 | ||
| PCT/CN2022/131893 WO2023088233A1 (en) | 2021-11-16 | 2022-11-15 | Lysine acetyltransferase 6a (kat6a) inhibitors and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024543512A JP2024543512A (ja) | 2024-11-21 |
| JP2024543512A5 true JP2024543512A5 (https=) | 2025-11-25 |
Family
ID=86396236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024529158A Pending JP2024543512A (ja) | 2021-11-16 | 2022-11-15 | リジンアセチルトランスフェラーゼ６ａ（ｋａｔ６ａ）阻害剤およびその使用 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20240109880A1 (https=) |
| EP (1) | EP4433474A4 (https=) |
| JP (1) | JP2024543512A (https=) |
| KR (1) | KR20240109267A (https=) |
| CN (1) | CN118556053A (https=) |
| AR (1) | AR127681A1 (https=) |
| AU (1) | AU2022390319A1 (https=) |
| CA (1) | CA3237830A1 (https=) |
| CL (1) | CL2024001466A1 (https=) |
| CO (1) | CO2024007129A2 (https=) |
| IL (1) | IL312696A (https=) |
| MX (1) | MX2024005839A (https=) |
| PE (1) | PE20241355A1 (https=) |
| TW (1) | TW202334163A (https=) |
| UY (1) | UY40021A (https=) |
| WO (1) | WO2023088233A1 (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3225068A1 (en) * | 2021-07-05 | 2023-01-12 | Hangzhou Innogate Pharma Co., Ltd. | Compound serving as kat6 inhibitor |
| CN118556053A (zh) | 2021-11-16 | 2024-08-27 | 英矽智能科技知识产权有限公司 | 赖氨酸乙酰基转移酶6a(kat6a)抑制剂及其用途 |
| WO2023114710A1 (en) | 2021-12-13 | 2023-06-22 | Aurigene Oncology Limited | Fused benzoisoxazolyl compounds as kat6a inhibitors |
| CN116621859A (zh) * | 2022-02-18 | 2023-08-22 | 山东轩竹医药科技有限公司 | 三并环类kat6抑制剂 |
| KR20250006833A (ko) | 2022-03-28 | 2025-01-13 | 아이소스테릭스, 인코포레이티드 | 라이신 아세틸 전이효소의 myst 계열의 억제제 |
| KR20250143814A (ko) * | 2023-02-10 | 2025-10-02 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | 설폰아미드 유도체 결정 형태 및 이의 제조 방법 |
| WO2024189598A2 (en) | 2023-03-16 | 2024-09-19 | Olema Pharmaceuticals, Inc. | Acylsulfonamide kat6a inhibitors |
| JP2026512835A (ja) * | 2023-03-27 | 2026-04-21 | ベイジン・コンランズ・ファーマシューティカル・カンパニー・リミテッド | スルホンアミド化合物、その医薬組成物及び応用 |
| AR132470A1 (es) * | 2023-04-19 | 2025-07-02 | Insilico Medicine Ip Ltd | Inhibidor de lisina-acetiltransferasa 6a (kat6a), combinaciones y usos del mismo |
| KR20260016479A (ko) * | 2023-04-25 | 2026-02-03 | 인실리코 메디신 아이피 리미티드 | 결정질 리신 아세틸트랜스퍼라제 6a (kat6a) 억제제 및 그의 용도 |
| AU2024290895A1 (en) * | 2023-07-04 | 2026-01-29 | Shanghai Qilu Pharmaceutical Research And Development Centre Ltd. | Kat6 inhibitor |
| AU2024325442A1 (en) * | 2023-08-14 | 2026-03-26 | Shanghai Henlius Biologics Co., Ltd. | Sulfonamide compound, and preparation method therefor and use thereof |
| TW202530223A (zh) * | 2023-09-27 | 2025-08-01 | 美商艾索司特瑞克斯公司 | Ｍｙｓｔ抑制劑 |
| CN117448454B (zh) * | 2023-10-30 | 2025-09-30 | 赣南医科大学 | Kat6a在制备结直肠癌肝转移诊断试剂盒中的应用 |
| WO2025098417A1 (zh) * | 2023-11-08 | 2025-05-15 | 再和医药科技（苏州）有限公司 | 磺酰胺类化合物及其应用 |
| WO2026053122A1 (en) | 2024-09-04 | 2026-03-12 | Dana-Farber Cancer Institute, Inc. | Methods of treating retinoid responsive cancers |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2457418T3 (es) | 2007-07-16 | 2014-04-25 | Abbvie Inc. | Indazoles, bencisoxazoles y bencisotiazoles como inhibidores de proteína cinasas |
| MX2015010775A (es) | 2013-03-15 | 2016-04-25 | Genentech Inc | Benzoxazoles sustituidos y metodos para usarlos. |
| GB201510019D0 (en) | 2015-06-09 | 2015-07-22 | Cancer Therapeutics Crc Pty Ltd | Compounds |
| EP3548480A1 (en) | 2016-11-29 | 2019-10-09 | Epizyme, Inc. | Compounds containing a sulfonic group as kat inhibitors |
| MX2020007131A (es) | 2017-11-29 | 2021-01-08 | Epizyme Inc | Inhibidores de histona acetiltransferasa de la familia myst. |
| GB201810092D0 (en) * | 2018-06-20 | 2018-08-08 | Ctxt Pty Ltd | Compounds |
| GB201810581D0 (en) | 2018-06-28 | 2018-08-15 | Ctxt Pty Ltd | Compounds |
| CA3137472A1 (en) | 2019-04-25 | 2020-10-29 | Bayer Aktiengesellschaft | Acyl sulfonamides for treating cancer |
| DK4299135T3 (da) * | 2019-06-18 | 2025-09-08 | Pfizer | Benzisoxazol-sulfonamid-derivater |
| US12545669B2 (en) * | 2019-06-19 | 2026-02-10 | Pfizer Inc. | Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives |
| FI4181920T3 (fi) | 2020-07-15 | 2025-11-20 | Pfizer | Kat6-estäjämenetelmät ja yhdistelmät syövän hoitoon |
| US20240279207A1 (en) | 2020-10-16 | 2024-08-22 | The Broad Institute, Inc. | Substituted acyl sulfonamides for treating cancer |
| WO2022081842A1 (en) | 2020-10-16 | 2022-04-21 | The Broad Institute, Inc. | Substituted acyl sulfonamides for treating cancer |
| US20240254139A1 (en) | 2021-05-21 | 2024-08-01 | Aurigene Oncology Limited | Fused isoxazolyl compounds as kat6a inhibitors |
| CA3225068A1 (en) | 2021-07-05 | 2023-01-12 | Hangzhou Innogate Pharma Co., Ltd. | Compound serving as kat6 inhibitor |
| US20250145637A1 (en) | 2021-08-10 | 2025-05-08 | Jiangsu Hengrui Pharmaceuticals Co. Ltd. | Sulfonamide derivative, preparation method therefor and medical use thereof |
| CN118556053A (zh) | 2021-11-16 | 2024-08-27 | 英矽智能科技知识产权有限公司 | 赖氨酸乙酰基转移酶6a(kat6a)抑制剂及其用途 |
| WO2023114710A1 (en) | 2021-12-13 | 2023-06-22 | Aurigene Oncology Limited | Fused benzoisoxazolyl compounds as kat6a inhibitors |
| KR20250006833A (ko) | 2022-03-28 | 2025-01-13 | 아이소스테릭스, 인코포레이티드 | 라이신 아세틸 전이효소의 myst 계열의 억제제 |
-
2022
- 2022-11-15 CN CN202280089104.7A patent/CN118556053A/zh active Pending
- 2022-11-15 UY UY0001040021A patent/UY40021A/es unknown
- 2022-11-15 IL IL312696A patent/IL312696A/en unknown
- 2022-11-15 CA CA3237830A patent/CA3237830A1/en active Pending
- 2022-11-15 AR ARP220103138A patent/AR127681A1/es unknown
- 2022-11-15 WO PCT/CN2022/131893 patent/WO2023088233A1/en not_active Ceased
- 2022-11-15 JP JP2024529158A patent/JP2024543512A/ja active Pending
- 2022-11-15 MX MX2024005839A patent/MX2024005839A/es unknown
- 2022-11-15 TW TW111143477A patent/TW202334163A/zh unknown
- 2022-11-15 EP EP22894767.7A patent/EP4433474A4/en active Pending
- 2022-11-15 AU AU2022390319A patent/AU2022390319A1/en active Pending
- 2022-11-15 PE PE2024001081A patent/PE20241355A1/es unknown
- 2022-11-15 KR KR1020247019546A patent/KR20240109267A/ko active Pending
-
2023
- 2023-10-13 US US18/486,369 patent/US20240109880A1/en active Pending
- 2023-11-13 US US18/507,566 patent/US12091406B2/en active Active
-
2024
- 2024-05-15 CL CL2024001466A patent/CL2024001466A1/es unknown
- 2024-06-05 CO CONC2024/0007129A patent/CO2024007129A2/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2024543512A5 (https=) | ||
| RU2403251C2 (ru) | Производные 2, 4-ди(гетеро)ариламинопиримидина в качестве ингибиторов zap-70 | |
| RU2363700C2 (ru) | Производные хинуклидина и фармацевтические композиции, содержащие их | |
| JP2006524222A5 (https=) | ||
| BR122012009489B8 (pt) | processo para produzir 2-etóxi-1-{[2-(5-oxo-4,5-diidro-1,2,4-oxadiazol-3-il)bifenil-4-il]metil}-1h-benzimidazol-7-carboxilato de (5-metil-2-oxo-1,3-dioxol-4-il)metila ou um sal do mesmo, composição farmacéutica, e, uso | |
| RU2005106846A (ru) | Производные бензотиазола, характеризующиеся агонистической активностью к бета-2-адренорецепторам | |
| AR046297A1 (es) | Inhibidores de la dpp - iv metodos para prepararlos y composiciones farmaceuticas que los contienen como agente activo | |
| JP2021522280A5 (https=) | ||
| JP2019527203A5 (https=) | ||
| JP2021523200A5 (https=) | ||
| JP2006501295A5 (https=) | ||
| RU2013138372A (ru) | Производные азетидина, применяемые для лечения метаболических и воспалительных заболеваний | |
| TW200519092A (en) | Malonamide derivatives | |
| PE20040898A1 (es) | Nuevos compuestos derivados de pirimidina | |
| CY1111980T1 (el) | Παραγωγα του αμιδιου τα οποια φερουν ενα υποκαταστατο του κυκλοπροπυλαμινοκαρβονυλιου και χρησιμευουν ως αναστολεις κυτταροκινης | |
| RU2010136665A (ru) | Новые пиридиноны и пиридазиноны | |
| AR042192A1 (es) | Derivados antivirales de nucleosidos de pirimidina | |
| JP2008526999A5 (https=) | ||
| JP2024532329A5 (https=) | ||
| JP2013515037A5 (https=) | ||
| JP2021513543A5 (https=) | ||
| JP2004525183A5 (https=) | ||
| RU2008119994A (ru) | Ингибиторы калиевых каналов | |
| JP2010513489A5 (https=) | ||
| JP2004517088A5 (https=) |