JP2024543377A5 - - Google Patents
Info
- Publication number
- JP2024543377A5 JP2024543377A5 JP2024527355A JP2024527355A JP2024543377A5 JP 2024543377 A5 JP2024543377 A5 JP 2024543377A5 JP 2024527355 A JP2024527355 A JP 2024527355A JP 2024527355 A JP2024527355 A JP 2024527355A JP 2024543377 A5 JP2024543377 A5 JP 2024543377A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- compound according
- groups
- independently selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163263875P | 2021-11-10 | 2021-11-10 | |
| US63/263,875 | 2021-11-10 | ||
| PCT/US2022/049426 WO2023086399A1 (en) | 2021-11-10 | 2022-11-09 | Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024543377A JP2024543377A (ja) | 2024-11-21 |
| JP2024543377A5 true JP2024543377A5 (https=) | 2025-11-07 |
Family
ID=85132852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024527355A Pending JP2024543377A (ja) | 2021-11-10 | 2022-11-09 | 造血前駆体キナーゼの二官能性分解物質およびその治療的使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US12091426B2 (https=) |
| EP (1) | EP4430052A1 (https=) |
| JP (1) | JP2024543377A (https=) |
| KR (1) | KR20240101654A (https=) |
| CN (1) | CN118510786A (https=) |
| AR (1) | AR127625A1 (https=) |
| AU (1) | AU2022388571A1 (https=) |
| CA (1) | CA3235913A1 (https=) |
| IL (1) | IL312361A (https=) |
| MX (1) | MX2024005431A (https=) |
| TW (1) | TW202334170A (https=) |
| WO (1) | WO2023086399A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2024008868A (es) | 2022-01-18 | 2024-09-23 | Maze Therapeutics Inc | Inhibidores de la apolipoproteína l1 (apol1) y métodos de uso. |
| WO2025029995A1 (en) * | 2023-08-01 | 2025-02-06 | Arvinas Operations, Inc. | Hpk1 targeting compounds and uses thereof |
| CN117126133A (zh) * | 2023-08-14 | 2023-11-28 | 中国海洋大学 | 一种化合物及其用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201600373YA (en) | 2013-07-31 | 2016-02-26 | Gilead Sciences Inc | Syk inhibitors |
| EP3710443A1 (en) | 2017-11-17 | 2020-09-23 | Arvinas Operations, Inc. | Compounds and methods for the targeted degradation of interleukin-1 receptor-associated kinase 4 polypeptides |
| IL315310A (en) | 2017-12-26 | 2024-10-01 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
| WO2020023851A1 (en) | 2018-07-26 | 2020-01-30 | Yale University | Bifunctional substitued pyrimidines as modulators of fak proteolyse |
| JP7472103B2 (ja) | 2018-08-22 | 2024-04-22 | クルゲン（シャンハイ），インク． | トロポミオシン受容体キナーゼ（ｔｒｋ）分解化合物とその使用方法 |
| WO2020092528A1 (en) * | 2018-10-31 | 2020-05-07 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity |
| US11203591B2 (en) | 2018-10-31 | 2021-12-21 | Gilead Sciences, Inc. | Substituted 6-azabenzimidazole compounds |
| JP7503851B2 (ja) | 2019-05-06 | 2024-06-21 | アイカーン スクール オブ メディスン アット マウント シナイ | Ｈｐｋ１の分解剤としてのヘテロ二官能性化合物 |
| WO2021168197A1 (en) | 2020-02-19 | 2021-08-26 | Nurix Therapeutics, Inc. | Bifunctional degraders of interleukin-1 receptor-associated kinases and therapeutic use thereof |
| US11739101B2 (en) * | 2020-05-06 | 2023-08-29 | Nurix Therapeutics, Inc. | Bifunctional degraders of hematopoietic progenitor kinase and therapeutic uses thereof |
-
2022
- 2022-11-09 AR ARP220103080A patent/AR127625A1/es unknown
- 2022-11-09 US US18/054,118 patent/US12091426B2/en active Active
- 2022-11-09 AU AU2022388571A patent/AU2022388571A1/en active Pending
- 2022-11-09 KR KR1020247019189A patent/KR20240101654A/ko active Pending
- 2022-11-09 JP JP2024527355A patent/JP2024543377A/ja active Pending
- 2022-11-09 CN CN202280087971.7A patent/CN118510786A/zh active Pending
- 2022-11-09 IL IL312361A patent/IL312361A/en unknown
- 2022-11-09 CA CA3235913A patent/CA3235913A1/en active Pending
- 2022-11-09 MX MX2024005431A patent/MX2024005431A/es unknown
- 2022-11-09 TW TW111142873A patent/TW202334170A/zh unknown
- 2022-11-09 WO PCT/US2022/049426 patent/WO2023086399A1/en not_active Ceased
- 2022-11-09 EP EP22850684.6A patent/EP4430052A1/en active Pending
-
2024
- 2024-08-07 US US18/797,148 patent/US20240400587A1/en active Pending
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