JP2024542199A5 - - Google Patents

Info

Publication number
JP2024542199A5
JP2024542199A5 JP2024529504A JP2024529504A JP2024542199A5 JP 2024542199 A5 JP2024542199 A5 JP 2024542199A5 JP 2024529504 A JP2024529504 A JP 2024529504A JP 2024529504 A JP2024529504 A JP 2024529504A JP 2024542199 A5 JP2024542199 A5 JP 2024542199A5
Authority
JP
Japan
Prior art keywords
hydrocarbyl
membered
halohydrocarbyl
general formula
optionally substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529504A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024542199A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/132954 external-priority patent/WO2023088441A1/zh
Publication of JP2024542199A publication Critical patent/JP2024542199A/ja
Publication of JP2024542199A5 publication Critical patent/JP2024542199A5/ja
Pending legal-status Critical Current

Links

JP2024529504A 2021-11-19 2022-11-18 Kif18a阻害剤 Pending JP2024542199A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CN202111399876 2021-11-19
CN202111399876.4 2021-11-19
CN202210225663.8 2022-03-09
CN202210225663 2022-03-09
CN202210667619 2022-06-13
CN202210667619.2 2022-06-13
PCT/CN2022/132954 WO2023088441A1 (zh) 2021-11-19 2022-11-18 Kif18a抑制剂

Publications (2)

Publication Number Publication Date
JP2024542199A JP2024542199A (ja) 2024-11-13
JP2024542199A5 true JP2024542199A5 (enExample) 2025-11-25

Family

ID=86396297

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529504A Pending JP2024542199A (ja) 2021-11-19 2022-11-18 Kif18a阻害剤

Country Status (9)

Country Link
US (1) US20260158017A1 (enExample)
EP (1) EP4434979A4 (enExample)
JP (1) JP2024542199A (enExample)
KR (1) KR20240108489A (enExample)
CN (1) CN118215657A (enExample)
AU (1) AU2022389558A1 (enExample)
CA (1) CA3237625A1 (enExample)
MX (1) MX2024005996A (enExample)
WO (1) WO2023088441A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL283639B2 (en) 2018-12-20 2024-06-01 Amgen Inc Kif18a inhibitors
KR20240109977A (ko) 2021-08-26 2024-07-12 볼라스트라 쎄라퓨틱스, 인코포레이티드 Kif18a의 스피로 인돌린 억제제
WO2024022508A1 (zh) * 2022-07-29 2024-02-01 武汉人福创新药物研发中心有限公司 Kif18a抑制剂及用途
CR20250087A (es) 2022-08-18 2025-07-11 Accent Therapeutics Inc Inhibidores de kif18a y usos de estos
CN117917405A (zh) * 2022-10-21 2024-04-23 杭州邦顺制药有限公司 Kif18a蛋白抑制剂
WO2024114730A1 (zh) * 2022-11-30 2024-06-06 微境生物医药科技(上海)有限公司 一种用于癌症治疗的药物组合物
JP2026508745A (ja) * 2022-12-02 2026-03-12 シェンチェン ジョングァー バイオロジカル テクノロジー カンパニー リミテッド アミド又はウレア系化合物
CN120569373A (zh) * 2023-01-05 2025-08-29 浙江海正药业股份有限公司 芳香酰胺类衍生物及其制备方法和医药上的用途
WO2024244972A1 (zh) * 2023-05-30 2024-12-05 浙江海正药业股份有限公司 芳香酰胺类衍生物及其制备方法和用途
EP4748837A1 (en) * 2023-07-21 2026-05-27 Zhejiang Hisun Pharmaceutical Co., Ltd. Aromatic amide derivative, and preparation method therefor and use thereof
CN121752573A (zh) * 2023-08-02 2026-03-27 上海湃隆生物科技有限公司 驱动蛋白kif18a抑制剂及其应用
CN121693499A (zh) * 2023-08-16 2026-03-17 上海湃隆生物科技有限公司 驱动蛋白kif18a抑制剂及其应用
WO2025190888A1 (en) * 2024-03-12 2025-09-18 F. Hoffmann-La Roche Ag Macrocyclic kif18a inhibitors and their use thereof
WO2025201407A1 (zh) * 2024-03-27 2025-10-02 上海齐鲁制药研究中心有限公司 驱动蛋白kif18a抑制剂及其使用方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO395396A0 (en) * 1996-12-02 1997-01-02 Fujisawa Pharmaceutical Co., Ltd. Benzamide derivatives
MA54550A (fr) * 2018-12-20 2022-03-30 Amgen Inc Inhibiteurs de kif18a
AU2019401495B2 (en) * 2018-12-20 2025-06-26 Amgen Inc. Heteroaryl amides useful as KIF18A inhibitors
AU2019404576B2 (en) * 2018-12-20 2025-07-17 Amgen Inc. Heteroaryl amides useful as KIF18A inhibitors
IL283639B2 (en) 2018-12-20 2024-06-01 Amgen Inc Kif18a inhibitors
AU2020325115B2 (en) * 2019-08-02 2026-03-12 Amgen Inc. Pyridine derivatives as KIF18A inhibitors
JP7699100B2 (ja) * 2019-08-02 2025-06-26 アムジエン・インコーポレーテツド Kif18a阻害剤
US20220289724A1 (en) * 2019-08-02 2022-09-15 Amgen Inc. Kif18a inhibitors
JP2023521802A (ja) * 2020-04-14 2023-05-25 アムジエン・インコーポレーテツド 新生物疾患の処置のためのkif18a阻害剤
KR20240070604A (ko) * 2021-09-24 2024-05-21 제논 파마슈티칼스 인크. 소듐 채널 활성화제로서 피리디닐아세트아미드 유도체

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