JP2024541900A - がんの治療のためのエンドキシフェン - Google Patents

がんの治療のためのエンドキシフェン Download PDF

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Publication number
JP2024541900A
JP2024541900A JP2024524402A JP2024524402A JP2024541900A JP 2024541900 A JP2024541900 A JP 2024541900A JP 2024524402 A JP2024524402 A JP 2024524402A JP 2024524402 A JP2024524402 A JP 2024524402A JP 2024541900 A JP2024541900 A JP 2024541900A
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JP
Japan
Prior art keywords
cancer
endoxifen
subject
response
treating
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Pending
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JP2024524402A
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English (en)
Japanese (ja)
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JP2024541900A5 (https=
Inventor
スティーブン シー． キー，
カーラ グランドリ，
カタニヤ カペリ，
Original Assignee
アトッサ・セラピューティクス・インコーポレイテッド
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Publication of JP2024541900A publication Critical patent/JP2024541900A/ja
Publication of JP2024541900A5 publication Critical patent/JP2024541900A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2024524402A 2021-10-28 2022-10-27 がんの治療のためのエンドキシフェン Pending JP2024541900A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163272869P 2021-10-28 2021-10-28
US63/272,869 2021-10-28
PCT/US2022/048061 WO2023076496A1 (en) 2021-10-28 2022-10-27 Endoxifen for treatment of cancers

Publications (2)

Publication Number Publication Date
JP2024541900A true JP2024541900A (ja) 2024-11-13
JP2024541900A5 JP2024541900A5 (https=) 2025-11-17

Family

ID=86158538

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024524402A Pending JP2024541900A (ja) 2021-10-28 2022-10-27 がんの治療のためのエンドキシフェン

Country Status (10)

Country Link
US (1) US20250041245A1 (https=)
EP (1) EP4422608A4 (https=)
JP (1) JP2024541900A (https=)
KR (1) KR20240093500A (https=)
CN (1) CN118159259A (https=)
AU (1) AU2022378576A1 (https=)
CA (1) CA3232972A1 (https=)
IL (1) IL312037A (https=)
MX (1) MX2024005220A (https=)
WO (1) WO2023076496A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4304574A4 (en) * 2021-03-11 2024-11-20 Atossa Therapeutics, Inc. ENDOXIFEN FOR THE TREATMENT OF OVARIAN CANCER
CN117338780A (zh) * 2023-09-21 2024-01-05 中国人民解放军海军军医大学 帕罗西汀在制备抗肿瘤药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013033430A1 (en) * 2011-09-02 2013-03-07 Wake Forest School Of Medicine Targeted delivery and prodrug designs for platinum-acridine anti-cancer compounds and methods thereof
ES2769634T3 (es) * 2011-11-04 2020-06-26 Szewczuk Myron R Uso de inhibidores de la sialidasa NEU1 en el tratamiento del cáncer
DE102015222031A1 (de) * 2015-11-10 2017-05-11 Robert Bosch Gesellschaft Für Medizinische Forschung Mbh Synthese von (Z)-Endoxifenhydrochlorid
WO2017127442A1 (en) * 2016-01-18 2017-07-27 The Regents Of The University Of California Methods for treating cancer with rorgamma inhibitors
JP7662204B2 (ja) * 2019-07-03 2025-04-15 アトッサ・セラピューティクス・インコーポレイテッド エンドキシフェンの徐放性組成物
JP7792335B2 (ja) * 2019-12-12 2025-12-25 センティ バイオサイエンシズ インコーポレイテッド 細胞の調節されたアーマリングのための方法及び組成物
EP4304574A4 (en) * 2021-03-11 2024-11-20 Atossa Therapeutics, Inc. ENDOXIFEN FOR THE TREATMENT OF OVARIAN CANCER
AU2023260712A1 (en) * 2022-04-26 2024-11-14 Atossa Therapeutics, Inc. High dose endoxifen formulations and methods of use

Also Published As

Publication number Publication date
EP4422608A4 (en) 2025-09-24
WO2023076496A1 (en) 2023-05-04
IL312037A (en) 2024-06-01
CA3232972A1 (en) 2023-05-04
AU2022378576A1 (en) 2024-03-28
CN118159259A (zh) 2024-06-07
EP4422608A1 (en) 2024-09-04
MX2024005220A (es) 2024-05-16
US20250041245A1 (en) 2025-02-06
KR20240093500A (ko) 2024-06-24

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