JP2024541321A - カプセル化した活性成分を含む顆粒 - Google Patents

カプセル化した活性成分を含む顆粒 Download PDF

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Publication number
JP2024541321A
JP2024541321A JP2024527377A JP2024527377A JP2024541321A JP 2024541321 A JP2024541321 A JP 2024541321A JP 2024527377 A JP2024527377 A JP 2024527377A JP 2024527377 A JP2024527377 A JP 2024527377A JP 2024541321 A JP2024541321 A JP 2024541321A
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JP
Japan
Prior art keywords
mixture
granules
binder
microcapsules
filler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024527377A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024541321A5 (https=
Inventor
ブラム べカルト，
クリストフ ポルティエ，
リーズ ヴァンデヴィヴェール，
クリス ヴェルヴァート，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of JP2024541321A publication Critical patent/JP2024541321A/ja
Publication of JP2024541321A5 publication Critical patent/JP2024541321A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A23P30/20—Extruding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A23P10/25—Agglomeration or granulation by extrusion or by pressing, e.g. through small holes, through sieves or between surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
JP2024527377A 2021-11-16 2022-11-16 カプセル化した活性成分を含む顆粒 Pending JP2024541321A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21208533.6 2021-11-16
EP21208533 2021-11-16
PCT/EP2022/082128 WO2023088962A1 (en) 2021-11-16 2022-11-16 Granule comprising encapsulated active ingredients

Publications (2)

Publication Number Publication Date
JP2024541321A true JP2024541321A (ja) 2024-11-08
JP2024541321A5 JP2024541321A5 (https=) 2025-11-10

Family

ID=78676359

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024527377A Pending JP2024541321A (ja) 2021-11-16 2022-11-16 カプセル化した活性成分を含む顆粒

Country Status (5)

Country Link
US (1) US20240423925A1 (https=)
EP (1) EP4432861B1 (https=)
JP (1) JP2024541321A (https=)
CN (1) CN118234387A (https=)
WO (1) WO2023088962A1 (https=)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2706660A1 (de) * 1977-02-17 1978-08-24 Merck Patent Gmbh Ascorbinsaeure enthaltende granulate und verfahren zu ihrer herstellung
JPH11196779A (ja) * 1998-01-07 1999-07-27 Nonogawa Shoji Kk 食品用顆粒組成物
ZA200003120B (en) * 1999-06-30 2001-01-02 Givaudan Roure Int Encapsulation of active ingredients.
AU2003277788A1 (en) * 2002-11-14 2004-06-03 Givaudan Sa Edible film containing food acid
DE50312862D1 (de) * 2003-08-22 2010-08-19 Coperion Gmbh Schneckenmaschine mit Misch- und Knet-Scheiben
JP4766648B2 (ja) * 2004-09-17 2011-09-07 トッパン・フォームズ株式会社 マイクロカプセル二次粒子とその製造方法ならびにマイクロカプセル含有樹脂組成物の製造方法
US8846088B2 (en) * 2005-02-03 2014-09-30 Takeda Nycomed As Melt granulation of a composition containing a calcium-containing compound
NZ562304A (en) * 2005-05-10 2010-06-25 Novartis Ag Extrusion process for making compositions with poorly compressible therapeutic compounds e.g. metformin hydrochloride
ES2327296T3 (es) * 2007-03-13 2009-10-27 Unilever N.V. Producto comestible de material compuesto que comprende aceite glicerido.
WO2017185040A1 (en) * 2016-04-22 2017-10-26 University Of Mississippi Twin-screw dry granulation for producing solid formulations
CN107823150A (zh) * 2017-10-25 2018-03-23 北京素维生物科技有限公司 一种可快速分散的片剂及其制备方法
WO2021213994A1 (en) * 2020-04-22 2021-10-28 Dsm Ip Assets B.V. Dietary powder for use in beverage-dispensing machines
CN113598397B (zh) * 2021-08-05 2022-10-25 仙乐健康科技股份有限公司 微囊化包埋颗粒以及其制备方法

Also Published As

Publication number Publication date
US20240423925A1 (en) 2024-12-26
EP4432861B1 (en) 2026-01-28
EP4432861A1 (en) 2024-09-25
CN118234387A (zh) 2024-06-21
WO2023088962A1 (en) 2023-05-25

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