CN118234387A - 包含封装的活性成分的颗粒 - Google Patents

包含封装的活性成分的颗粒 Download PDF

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Publication number
CN118234387A
CN118234387A CN202280075701.4A CN202280075701A CN118234387A CN 118234387 A CN118234387 A CN 118234387A CN 202280075701 A CN202280075701 A CN 202280075701A CN 118234387 A CN118234387 A CN 118234387A
Authority
CN
China
Prior art keywords
mixture
microcapsules
binder
filler
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202280075701.4A
Other languages
English (en)
Chinese (zh)
Inventor
布拉姆·贝卡尔特
克里斯托夫·波蒂尔
莉丝·范德维尔
克里斯·维瓦特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of CN118234387A publication Critical patent/CN118234387A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A23P30/20—Extruding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/20—Agglomerating; Granulating; Tabletting
    • A23P10/25—Agglomeration or granulation by extrusion or by pressing, e.g. through small holes, through sieves or between surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Manufacturing & Machinery (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
CN202280075701.4A 2021-11-16 2022-11-16 包含封装的活性成分的颗粒 Pending CN118234387A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21208533.6 2021-11-16
EP21208533 2021-11-16
PCT/EP2022/082128 WO2023088962A1 (en) 2021-11-16 2022-11-16 Granule comprising encapsulated active ingredients

Publications (1)

Publication Number Publication Date
CN118234387A true CN118234387A (zh) 2024-06-21

Family

ID=78676359

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202280075701.4A Pending CN118234387A (zh) 2021-11-16 2022-11-16 包含封装的活性成分的颗粒

Country Status (5)

Country Link
US (1) US20240423925A1 (https=)
EP (1) EP4432861B1 (https=)
JP (1) JP2024541321A (https=)
CN (1) CN118234387A (https=)
WO (1) WO2023088962A1 (https=)

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203997A (en) * 1977-02-17 1980-05-20 Merck Patent Gesellschaft Mit Beschrankter Haftung Directly-pressable ascorbic acid-containing granulates
JPH11196779A (ja) * 1998-01-07 1999-07-27 Nonogawa Shoji Kk 食品用顆粒組成物
US6482433B1 (en) * 1999-06-30 2002-11-19 Givaudan Sa Encapsulation of active ingredients
CN1583396A (zh) * 2003-08-22 2005-02-23 科倍隆W&P有限及两合公司 带混合搅拌盘螺旋式挤出机
US20060035008A1 (en) * 2002-11-14 2006-02-16 Givaudan Sa Edible film containing food acid
JP2006083340A (ja) * 2004-09-17 2006-03-30 Toppan Forms Co Ltd マイクロカプセル二次粒子とその製造方法ならびにマイクロカプセル含有樹脂組成物の製造方法
WO2006082499A1 (en) * 2005-02-03 2006-08-10 Nycomed Pharma As Melt granulation of a composition containing a calcium-containing compound
US20080226772A1 (en) * 2007-03-13 2008-09-18 Conopco, Inc. D/B/A Unilever Composite edible product comprising glygeride oil
CN102552162A (zh) * 2005-05-10 2012-07-11 诺瓦提斯公司 制备含有可压性差的治疗性化合物的组合物的挤压方法
US20170319486A1 (en) * 2016-04-22 2017-11-09 Catalent Pharma Solutions Inc. Twin-screw dry granulation for producing solid formulations
WO2021213994A1 (en) * 2020-04-22 2021-10-28 Dsm Ip Assets B.V. Dietary powder for use in beverage-dispensing machines

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107823150A (zh) * 2017-10-25 2018-03-23 北京素维生物科技有限公司 一种可快速分散的片剂及其制备方法
CN113598397B (zh) * 2021-08-05 2022-10-25 仙乐健康科技股份有限公司 微囊化包埋颗粒以及其制备方法

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203997A (en) * 1977-02-17 1980-05-20 Merck Patent Gesellschaft Mit Beschrankter Haftung Directly-pressable ascorbic acid-containing granulates
JPH11196779A (ja) * 1998-01-07 1999-07-27 Nonogawa Shoji Kk 食品用顆粒組成物
US6482433B1 (en) * 1999-06-30 2002-11-19 Givaudan Sa Encapsulation of active ingredients
US20060035008A1 (en) * 2002-11-14 2006-02-16 Givaudan Sa Edible film containing food acid
CN1583396A (zh) * 2003-08-22 2005-02-23 科倍隆W&P有限及两合公司 带混合搅拌盘螺旋式挤出机
JP2006083340A (ja) * 2004-09-17 2006-03-30 Toppan Forms Co Ltd マイクロカプセル二次粒子とその製造方法ならびにマイクロカプセル含有樹脂組成物の製造方法
WO2006082499A1 (en) * 2005-02-03 2006-08-10 Nycomed Pharma As Melt granulation of a composition containing a calcium-containing compound
CN102552162A (zh) * 2005-05-10 2012-07-11 诺瓦提斯公司 制备含有可压性差的治疗性化合物的组合物的挤压方法
US20080226772A1 (en) * 2007-03-13 2008-09-18 Conopco, Inc. D/B/A Unilever Composite edible product comprising glygeride oil
US20170319486A1 (en) * 2016-04-22 2017-11-09 Catalent Pharma Solutions Inc. Twin-screw dry granulation for producing solid formulations
WO2021213994A1 (en) * 2020-04-22 2021-10-28 Dsm Ip Assets B.V. Dietary powder for use in beverage-dispensing machines

Also Published As

Publication number Publication date
US20240423925A1 (en) 2024-12-26
JP2024541321A (ja) 2024-11-08
EP4432861B1 (en) 2026-01-28
EP4432861A1 (en) 2024-09-25
WO2023088962A1 (en) 2023-05-25

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