JP2024540994A5 - - Google Patents

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Publication number
JP2024540994A5
JP2024540994A5 JP2024524371A JP2024524371A JP2024540994A5 JP 2024540994 A5 JP2024540994 A5 JP 2024540994A5 JP 2024524371 A JP2024524371 A JP 2024524371A JP 2024524371 A JP2024524371 A JP 2024524371A JP 2024540994 A5 JP2024540994 A5 JP 2024540994A5
Authority
JP
Japan
Prior art keywords
dna
cytoplasmic
inhibitor
sensing inhibitor
nanoparticle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024524371A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540994A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/074084 external-priority patent/WO2023004437A1/en
Publication of JP2024540994A publication Critical patent/JP2024540994A/ja
Publication of JP2024540994A5 publication Critical patent/JP2024540994A5/ja
Pending legal-status Critical Current

Links

JP2024524371A 2021-07-23 2022-07-22 非ウイルス性dna送達のための方法および組成物 Pending JP2024540994A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163203451P 2021-07-23 2021-07-23
US63/203,451 2021-07-23
PCT/US2022/074084 WO2023004437A1 (en) 2021-07-23 2022-07-22 Method of enhancing gene therapy by targeting cgas-sting pathway

Publications (2)

Publication Number Publication Date
JP2024540994A JP2024540994A (ja) 2024-11-06
JP2024540994A5 true JP2024540994A5 (https=) 2025-07-25

Family

ID=84980517

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024524371A Pending JP2024540994A (ja) 2021-07-23 2022-07-22 非ウイルス性dna送達のための方法および組成物

Country Status (10)

Country Link
US (1) US20240350667A1 (https=)
EP (1) EP4373946A4 (https=)
JP (1) JP2024540994A (https=)
KR (1) KR20240083170A (https=)
CN (1) CN117980487A (https=)
AU (1) AU2022316228A1 (https=)
CA (1) CA3230386A1 (https=)
CO (1) CO2024002065A2 (https=)
IL (1) IL311167A (https=)
WO (1) WO2023004437A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024054901A1 (en) * 2022-09-09 2024-03-14 Spark Therapeutics, Inc. Piperazine compounds
CN117682973B (zh) * 2022-09-26 2026-03-20 中国药科大学 磺酰胺类化合物及其医药用途
WO2025265081A1 (en) * 2024-06-21 2025-12-26 Stylus Medicine, Inc. cGAS-STING PATHWAY INHIBITORS AND USES THEREOF
CN118908937B (zh) * 2024-07-10 2025-07-15 中山大学中山眼科中心 一种具有sting蛋白降解作用的化合物及其制备方法和用途
CN119185549B (zh) * 2024-10-25 2025-09-02 四川大学华西医院 Sting抑制剂在制备治疗或预防心脏骤停后综合征药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130037977A1 (en) * 2010-04-08 2013-02-14 Paul A. Burke Preparation of Lipid Nanoparticles
EP2934598B1 (en) * 2012-12-19 2018-04-18 Board Of Regents, The University Of Texas System Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
JP2022518504A (ja) * 2019-01-24 2022-03-15 ジェネレーション バイオ カンパニー 閉端dna(cedna)ならびに遺伝子療法または核酸療法に関連する免疫応答を低減させる方法における使用
EP4061403A4 (en) * 2019-11-19 2023-12-27 Spark Therapeutics, Inc. Secretable protein induced immune tolerization and treatment of autoimmune, allergic and other diseases and disorders

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