JP2024540461A5 - - Google Patents
Info
- Publication number
- JP2024540461A5 JP2024540461A5 JP2024529262A JP2024529262A JP2024540461A5 JP 2024540461 A5 JP2024540461 A5 JP 2024540461A5 JP 2024529262 A JP2024529262 A JP 2024529262A JP 2024529262 A JP2024529262 A JP 2024529262A JP 2024540461 A5 JP2024540461 A5 JP 2024540461A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- heavy chain
- light chain
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2021/131804 WO2023087255A1 (zh) | 2021-11-19 | 2021-11-19 | 双特异性抗体及其应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024540461A JP2024540461A (ja) | 2024-10-31 |
| JP2024540461A5 true JP2024540461A5 (cg-RX-API-DMAC10.html) | 2025-08-28 |
| JP7868145B2 JP7868145B2 (ja) | 2026-06-01 |
Family
ID=86395992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024529262A Active JP7868145B2 (ja) | 2021-11-19 | 2021-11-19 | 二重特異性抗体及びその用途 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20250002605A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP4435006A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7868145B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR20240100453A (cg-RX-API-DMAC10.html) |
| CN (3) | CN118201960B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2021474386A1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3238406A1 (cg-RX-API-DMAC10.html) |
| MX (1) | MX2024006079A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2023087255A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025190337A1 (zh) * | 2024-03-13 | 2025-09-18 | 武汉友芝友生物制药股份有限公司 | 使用抗EpCAM×CD3双特异性抗体改善或治疗恶性腹水的方法 |
| CN120346170B (zh) * | 2025-03-13 | 2026-07-03 | 武汉友芝友生物制药股份有限公司 | 抗EpCAM和CD3双特异性抗体药物组合物 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| AU2004242845B2 (en) * | 2003-05-31 | 2011-06-02 | Amgen Research (Munich) Gmbh | Human-anti-human CD3 binding molecules |
| NZ543202A (en) * | 2003-05-31 | 2008-04-30 | Micromet Ag | Pharmaceutical composition comprising a bispecific antibody for epcam |
| US8076459B2 (en) * | 2003-10-16 | 2011-12-13 | Micromet Ag | Multispecfic deimmunized CD3-binders |
| KR101837053B1 (ko) | 2008-10-01 | 2018-03-12 | 암젠 리서치 (뮌헨) 게엠베하 | 종간 특이적 ＰＳＣＡｘＣＤ３, ＣＤ19ｘＣＤ3, ｃ-ＭＥＴｘＣＤ3, 엔도시알린ｘＣＤ3, ＥｐＣＡＭｘＣＤ3, ＩＧＦ-1ＲｘＣＤ3 또는 ＦＡＰαｘＣＤ3 이중특이적 단일쇄 항체 |
| RU2012115480A (ru) | 2009-09-18 | 2013-10-27 | Микромет Аг | РЕЖИМ ДОЗИРОВАНИЯ ПРИ ВВЕДЕНИИ БИСПЕЦИФИЧЕСКОГО АНТИТЕЛА EpCAMxCD3 |
| TWI736437B (zh) * | 2010-11-30 | 2021-08-11 | 日商中外製藥股份有限公司 | 細胞傷害誘導治療劑 |
| US9382329B2 (en) * | 2012-08-14 | 2016-07-05 | Ibc Pharmaceuticals, Inc. | Disease therapy by inducing immune response to Trop-2 expressing cells |
| US10647768B2 (en) | 2014-05-29 | 2020-05-12 | Macrogenics, Inc. | Multi-chain polypeptide-containing tri-specific binding molecules |
| CN104592392B (zh) * | 2015-01-21 | 2018-08-28 | 武汉友芝友生物制药有限公司 | 一种双特异性抗体EpCAM×CD3的构建及应用 |
| CN104592391B (zh) * | 2015-01-21 | 2020-08-21 | 武汉友芝友生物制药有限公司 | 一种双特异性抗体EpCAM×CD3的构建及应用 |
| US20190170752A1 (en) * | 2016-08-08 | 2019-06-06 | Beigene, Ltd. | Method for predicting efficacy of immune checkpoint inhibitors in cancer patients |
| KR102491752B1 (ko) * | 2016-08-29 | 2023-01-26 | 싸이오서스 테라퓨틱스 엘티디. | 이중특이성 T 세포 세포 관여자(BiTE)가 보강된 아데노바이러스 |
| JP7621263B2 (ja) * | 2019-02-22 | 2025-01-24 | 武▲漢▼友芝友生物制▲薬▼股▲ふん▼有限公司 | 改変されたＦｃ断片、それを含む抗体、及びそれらの使用 |
| US20220340677A1 (en) * | 2019-09-09 | 2022-10-27 | Wuhan Yzy Biopharma Co., Ltd. | Split intein and preparation method for recombinant polypeptide using the same |
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2021
- 2021-11-19 CA CA3238406A patent/CA3238406A1/en active Pending
- 2021-11-19 EP EP21964409.3A patent/EP4435006A4/en active Pending
- 2021-11-19 CN CN202180104172.1A patent/CN118201960B/zh active Active
- 2021-11-19 MX MX2024006079A patent/MX2024006079A/es unknown
- 2021-11-19 JP JP2024529262A patent/JP7868145B2/ja active Active
- 2021-11-19 KR KR1020247020170A patent/KR20240100453A/ko active Pending
- 2021-11-19 US US18/711,094 patent/US20250002605A1/en active Pending
- 2021-11-19 CN CN202510748238.0A patent/CN120818062A/zh active Pending
- 2021-11-19 CN CN202510748232.3A patent/CN120818061A/zh active Pending
- 2021-11-19 AU AU2021474386A patent/AU2021474386A1/en active Pending
- 2021-11-19 WO PCT/CN2021/131804 patent/WO2023087255A1/zh not_active Ceased