JP2024540181A5 - - Google Patents
Info
- Publication number
- JP2024540181A5 JP2024540181A5 JP2024525653A JP2024525653A JP2024540181A5 JP 2024540181 A5 JP2024540181 A5 JP 2024540181A5 JP 2024525653 A JP2024525653 A JP 2024525653A JP 2024525653 A JP2024525653 A JP 2024525653A JP 2024540181 A5 JP2024540181 A5 JP 2024540181A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- aav
- recombinant aav
- capsid
- binding pair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163275731P | 2021-11-04 | 2021-11-04 | |
| US63/275,731 | 2021-11-04 | ||
| US202263369761P | 2022-07-28 | 2022-07-28 | |
| US63/369,761 | 2022-07-28 | ||
| PCT/US2022/079339 WO2023081850A1 (en) | 2021-11-04 | 2022-11-04 | Viral particles retargeted to skeletal muscle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024540181A JP2024540181A (ja) | 2024-10-31 |
| JP2024540181A5 true JP2024540181A5 (https=) | 2025-11-11 |
Family
ID=84537880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024525653A Pending JP2024540181A (ja) | 2021-11-04 | 2022-11-04 | 骨格筋に再標的化されたウイルス粒子 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20250304918A1 (https=) |
| EP (1) | EP4426359A1 (https=) |
| JP (1) | JP2024540181A (https=) |
| KR (1) | KR20240095211A (https=) |
| CN (1) | CN118201643A (https=) |
| AU (1) | AU2022380841A1 (https=) |
| CA (1) | CA3233698A1 (https=) |
| CL (2) | CL2024001307A1 (https=) |
| CO (1) | CO2024005350A2 (https=) |
| IL (1) | IL312598A (https=) |
| MX (1) | MX2024005314A (https=) |
| PE (1) | PE20241212A1 (https=) |
| WO (1) | WO2023081850A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4612184A1 (en) * | 2022-11-04 | 2025-09-10 | Regeneron Pharmaceuticals, Inc. | Calcium voltage-gated channel auxiliary subunit gamma 1 (cacng1) binding proteins and cacng1-mediated delivery to skeletal muscle |
| EP4665764A1 (en) * | 2023-02-13 | 2025-12-24 | Regeneron Pharmaceuticals, Inc. | Treatment of muscle related disorders with anti-human cacng1 antibodies |
| CN121568720A (zh) * | 2023-07-10 | 2026-02-24 | 瑞泽恩制药公司 | 抗人类cacng1抗体-药物缀合物及其用途 |
| TW202528546A (zh) * | 2023-09-07 | 2025-07-16 | 美商再生元醫藥公司 | 經共價表面修飾之腺相關病毒的生產及純化 |
| WO2025087345A1 (en) * | 2023-10-25 | 2025-05-01 | Suzhou Cure Genetics Biosciences Co., Limited | Targeted viral particles |
| WO2026037757A1 (en) | 2024-08-13 | 2026-02-19 | F. Hoffmann-La Roche Ag | Modified aav particles |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2224907A1 (en) | 1995-07-25 | 1997-02-13 | Introgene B.V. | Methods and means for targeted gene delivery |
| WO1998011244A2 (en) | 1996-09-11 | 1998-03-19 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Aav4 vector and uses thereof |
| US6156303A (en) | 1997-06-11 | 2000-12-05 | University Of Washington | Adeno-associated virus (AAV) isolates and AAV vectors derived therefrom |
| WO1999061601A2 (en) | 1998-05-28 | 1999-12-02 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Aav5 vector and uses thereof |
| ATE362542T1 (de) | 1998-11-05 | 2007-06-15 | Univ Pennsylvania | Nukleinsäuresequenzen des adeno-assoziierten virus des serotyps i, und vektoren und wirtszellen, die diese enthalten |
| ES2602610T3 (es) | 2007-05-31 | 2017-02-21 | Medigene Ag | Proteína estructural mutada de un parvovirus |
| US8236557B2 (en) | 2008-05-28 | 2012-08-07 | University Of Missouri-Columbia | Hybrid-AAV vectors to deliver large gene expression cassette |
| ES2724975T3 (es) | 2009-12-10 | 2019-09-18 | Regeneron Pharma | Ratones que producen anticuerpos de cadena pesada |
| GB201002362D0 (en) | 2010-02-11 | 2010-03-31 | Isis Innovation | Peptide tag systems that spontaneously form an irreversible link to protein partners via isopeptide bonds |
| CA3124228C (en) | 2014-03-21 | 2024-05-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
| EP3151866B1 (en) | 2014-06-09 | 2023-03-08 | Voyager Therapeutics, Inc. | Chimeric capsids |
| JP6832280B2 (ja) | 2015-01-16 | 2021-02-24 | ユニバーシティ オブ ワシントンＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｗａｓｈｉｎｇｔｏｎ | 新規のマイクロジストロフィンおよび使用の関連する方法 |
| CN117887804A (zh) | 2017-02-02 | 2024-04-16 | 纽约基因组研究中心公司 | 用于识别或量化在生物样品中的靶标的方法和组合物 |
| PE20200488A1 (es) | 2017-06-27 | 2020-03-03 | Regeneron Pharma | Vectores virales recombinantes con tropismo modificado y usos de estos para la introduccion dirigida de material genetico a celulas humanas |
| ES2996886T3 (en) | 2017-06-27 | 2025-02-13 | Regeneron Pharma | Rodents comprising a humanized asgr1 locus |
| LT3645553T (lt) | 2017-06-27 | 2023-04-25 | Regeneron Pharmaceuticals, Inc. | Modifikuoto tropizmo rekombinantinės viruso dalelės ir jų panaudojimas genetinės medžiagos tiksliniam įvedimui į žmogaus ląsteles |
| WO2019084015A1 (en) | 2017-10-23 | 2019-05-02 | Daniel Schmidt | PROGRAMMABLE SET OF VIRUS COMPOSITES FOR ADMINISTRATION OF GENES TARGETING A RECEPTOR |
| US12258597B2 (en) * | 2018-02-07 | 2025-03-25 | Regeneron Pharmaceuticals, Inc. | Methods and compositions for therapeutic protein delivery |
| US20220028234A1 (en) | 2020-02-27 | 2022-01-27 | Mirza Faizan | Active security system and a method to detect and neutralize armed intruders |
-
2022
- 2022-11-04 JP JP2024525653A patent/JP2024540181A/ja active Pending
- 2022-11-04 CN CN202280073053.9A patent/CN118201643A/zh active Pending
- 2022-11-04 MX MX2024005314A patent/MX2024005314A/es unknown
- 2022-11-04 US US18/707,217 patent/US20250304918A1/en active Pending
- 2022-11-04 AU AU2022380841A patent/AU2022380841A1/en active Pending
- 2022-11-04 EP EP22826538.5A patent/EP4426359A1/en active Pending
- 2022-11-04 KR KR1020247013639A patent/KR20240095211A/ko active Pending
- 2022-11-04 PE PE2024000991A patent/PE20241212A1/es unknown
- 2022-11-04 CA CA3233698A patent/CA3233698A1/en active Pending
- 2022-11-04 WO PCT/US2022/079339 patent/WO2023081850A1/en not_active Ceased
- 2022-11-04 IL IL312598A patent/IL312598A/en unknown
-
2024
- 2024-04-25 CO CONC2024/0005350A patent/CO2024005350A2/es unknown
- 2024-04-29 CL CL2024001307A patent/CL2024001307A1/es unknown
-
2025
- 2025-03-21 CL CL2025000839A patent/CL2025000839A1/es unknown
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