JP2024536496A5 - - Google Patents

Info

Publication number
JP2024536496A5
JP2024536496A5 JP2024522229A JP2024522229A JP2024536496A5 JP 2024536496 A5 JP2024536496 A5 JP 2024536496A5 JP 2024522229 A JP2024522229 A JP 2024522229A JP 2024522229 A JP2024522229 A JP 2024522229A JP 2024536496 A5 JP2024536496 A5 JP 2024536496A5
Authority
JP
Japan
Prior art keywords
cells
thymocytes
vpe
combination
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024522229A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024536496A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/046551 external-priority patent/WO2023064457A1/en
Publication of JP2024536496A publication Critical patent/JP2024536496A/ja
Publication of JP2024536496A5 publication Critical patent/JP2024536496A5/ja
Pending legal-status Critical Current

Links

JP2024522229A 2021-10-15 2022-10-13 胸腺細胞及びその製造方法 Pending JP2024536496A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163256443P 2021-10-15 2021-10-15
US63/256,443 2021-10-15
US202263296251P 2022-01-04 2022-01-04
US63/296,251 2022-01-04
US202263321136P 2022-03-18 2022-03-18
US63/321,136 2022-03-18
US202263388407P 2022-07-12 2022-07-12
US63/388,407 2022-07-12
PCT/US2022/046551 WO2023064457A1 (en) 2021-10-15 2022-10-13 Thymic cells and methods of making

Publications (2)

Publication Number Publication Date
JP2024536496A JP2024536496A (ja) 2024-10-04
JP2024536496A5 true JP2024536496A5 (cg-RX-API-DMAC7.html) 2025-08-22

Family

ID=85988846

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024522229A Pending JP2024536496A (ja) 2021-10-15 2022-10-13 胸腺細胞及びその製造方法

Country Status (8)

Country Link
US (1) US20240417687A1 (cg-RX-API-DMAC7.html)
EP (1) EP4416267A4 (cg-RX-API-DMAC7.html)
JP (1) JP2024536496A (cg-RX-API-DMAC7.html)
KR (1) KR20240075885A (cg-RX-API-DMAC7.html)
AU (1) AU2022366819A1 (cg-RX-API-DMAC7.html)
CA (1) CA3234507A1 (cg-RX-API-DMAC7.html)
IL (1) IL311994A (cg-RX-API-DMAC7.html)
WO (1) WO2023064457A1 (cg-RX-API-DMAC7.html)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024211601A1 (en) * 2023-04-05 2024-10-10 Thymmune Therapeutics, Inc. Thymic cell compositions and methods of making
WO2025250531A1 (en) * 2024-05-28 2025-12-04 Thymmune Therapeutics, Inc. Hypoimmune engineering for universal ipsc-derived cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6274510B2 (ja) * 2012-01-27 2018-02-07 国立大学法人京都大学 多能性幹細胞の心筋分化誘導法
JP6494515B2 (ja) * 2012-10-19 2019-04-03 エージェンシー フォー サイエンス, テクノロジー アンド リサーチ 幹細胞を1又は2以上の細胞系列に分化させる方法
KR102084561B1 (ko) * 2012-12-31 2020-03-04 얀센 바이오테크 인코포레이티드 췌장 내분비 세포로의 분화를 위한 공기-액체 계면에서의 인간 배아 줄기세포의 배양
WO2014134213A1 (en) * 2013-02-27 2014-09-04 The Regents Of The University Of California Generation of thymic epithelial progenitor cells in vitro
WO2019060336A1 (en) * 2017-09-20 2019-03-28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services IN VITRO GENERATION OF THYMIC ORGANOID FROM HUMAN PLURIPOTENT STEM CELLS
JP7740706B2 (ja) * 2019-04-01 2025-09-17 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク 多能性幹細胞の胸腺上皮細胞および胸腺上皮前駆細胞分化を促進する方法

Similar Documents

Publication Publication Date Title
RU2764465C1 (ru) Дифференцировка in vitro плюрипотентных стволовых клеток в панкреатические эндодермальные клетки (пэк) и эндокринные клетки
US9732322B2 (en) Compositions for mesoderm derived ISL1+ multipotent cells (IMPs), epicardial progenitor cells (EPCs) and multipotent C56C cells (C56Cs) and methods of producing and using same
KR101592180B1 (ko) 인간 영양 세포를 이용한 만능 줄기 세포 분화
KR101651661B1 (ko) 만능 줄기 세포의 분화
KR101592182B1 (ko) 인간 배아 줄기 세포의 분화
Foley et al. Heart induction: embryology to cardiomyocyte regeneration
US9175260B2 (en) Early mesoderm cells, a stable population of mesendoderm cells that has utility for generation of endoderm and mesoderm lineages and multipotent migratory cells (MMC)
EP2318520B1 (en) Compositions for mesoderm derived isl1+ multipotent cells (imps), epicardial progenitor cells (epcs) and multipotent cxcr4+cd56+ cells (c56cs) and methods of use
AU2005272681B2 (en) Compositions and methods for self-renewal and differentiation in human embryonic stem cells
CN101541953A (zh) 通过从人胚胎干细胞获得的定形内胚层细胞的分化得到胰和肝内胚层细胞及组织
JP2024153768A5 (cg-RX-API-DMAC7.html)
CN117448267B (zh) 一种用于骨关节炎药物的间充质干细胞构建方法与应用
WO2019177118A1 (ja) 多能性幹細胞から各種細胞への段階的製造方法
KR20250157326A (ko) 3차원 장관 오가노이드 유래 장 줄기세포 집합체 배양을 위한 화학적 조성이 명확한 2차원 배양법
EP4600349A1 (en) Stromal cell layer around intestinal organoid for enhancing engraftment and regeneration efficacy, and use thereof
CN113234664B (zh) 一种胰腺祖细胞的制备方法及其应用
WO2024070494A1 (ja) 膵内胚葉細胞の製造方法
US20240076618A1 (en) Generation of induced human thymic epithelial cells and its application in cell-based immunotherapies
RU2430158C1 (ru) Способ дифференцировки стволовых клеток взрослого человека в клетки, секретирующие инсулин
JP2023542973A (ja) ラフト培養物及びその作製方法
RU2782271C2 (ru) Дифференцирование эмбриональных стволовых клеток человека
CN116057171A (zh) 羊膜样上皮细胞的产生
JP2025509641A5 (cg-RX-API-DMAC7.html)
FR3151340A1 (fr) Différenciation neurale à partir de cellules pluripotentes
CN121013904A (zh) 临床级类器官