JP2024534667A - 神経系疾患の直接分化転換治療 - Google Patents

神経系疾患の直接分化転換治療 Download PDF

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JP2024534667A
JP2024534667A JP2024519557A JP2024519557A JP2024534667A JP 2024534667 A JP2024534667 A JP 2024534667A JP 2024519557 A JP2024519557 A JP 2024519557A JP 2024519557 A JP2024519557 A JP 2024519557A JP 2024534667 A JP2024534667 A JP 2024534667A
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glial cells
neurons
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JPWO2023051802A5 (enExample
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ハイポー チョウ
シントー フー
チンリン スー
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シャンハイ ジェネマジック バイオサイエンシズ カンパニー,リミティド
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JP2024519557A 2021-09-30 2022-09-30 神経系疾患の直接分化転換治療 Pending JP2024534667A (ja)

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CN202111158620.4 2021-09-30
CN202111158620.4A CN115887655B (zh) 2021-09-30 2021-09-30 直接转分化治疗神经系统疾病
PCT/CN2022/123409 WO2023051802A1 (zh) 2021-09-30 2022-09-30 直接转分化治疗神经系统疾病

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JP2024534667A true JP2024534667A (ja) 2024-09-20
JPWO2023051802A5 JPWO2023051802A5 (enExample) 2025-10-08

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WO2024199511A1 (zh) * 2023-03-30 2024-10-03 上海鲸奇生物科技有限公司 治疗神经系统疾病的表达载体和组合物
WO2025173411A1 (ja) * 2024-02-14 2025-08-21 国立大学法人筑波大学 網膜神経節細胞分化誘導用キット、医薬組成物及び緑内障モデル

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FR2774698B1 (fr) * 1998-02-12 2002-03-01 Rhone Poulenc Rorer Sa Utilisation d'elements de regulation negative pour l'expression neurospecifique de transgenes
ITVA20060041A1 (it) * 2006-07-05 2008-01-06 Dialectica Srl Uso di composti derivati amminotiazolici, di loro composizioni farmaceutiche, nel trattamento di malattie caratterizzate dalla anormale repressione della trascrizione genica, particolarmente il morbo di huntington
CA2704314A1 (en) * 2007-11-02 2009-05-07 Nederlands Instituut Voor Neurowetenschappen Polypeptides involved in neuronal regeneration-associated gene expression
WO2011099502A1 (ja) * 2010-02-10 2011-08-18 公立大学法人横浜市立大学 神経選択的転写抑制因子NRSFに特異的に結合するmSin3B に結合する化合物の利用
US20150299698A1 (en) * 2012-11-01 2015-10-22 The Regents Of The University Of California Methods for engineering non-neuronal cells into neurons and using newly engineered neurons to treat neurodegenerative diseases
US20160031958A1 (en) * 2014-08-01 2016-02-04 Oregon Health & Science University Methods and compositions useful in manipulating the stability of re1 silencing transcription factor
CA3062995A1 (en) * 2017-05-12 2018-11-15 New York Stem Cell Foundation, Inc. Systems
GB202017810D0 (en) * 2018-04-11 2020-12-23 Univ California Reprogramming of non-neuronal cells into neurons and methods and compositions to treat neurodegenerative diseases and disorders
CA3103663A1 (en) * 2018-06-18 2019-12-26 University Of Rochester Inhibition of re1-silencing transcription factor in the treatment of schizophrenia and other neuropsychiatric disorders
IL293165A (en) * 2019-11-22 2022-07-01 Alcamena Stem Cell Therapeutics Llc Compositions and methods for silencing transcription factor re1 target genes

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WO2023051802A1 (zh) 2023-04-06
US20250115650A1 (en) 2025-04-10
CN118201623A (zh) 2024-06-14
EP4410296A4 (en) 2025-10-15
CN115887655B (zh) 2025-06-17
CN115887655A (zh) 2023-04-04
EP4410296A1 (en) 2024-08-07

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