JP2024534517A - Ｅｒｂｂ阻害剤としての多形 - Google Patents
Ｅｒｂｂ阻害剤としての多形 Download PDFInfo
- Publication number
- JP2024534517A JP2024534517A JP2024517482A JP2024517482A JP2024534517A JP 2024534517 A JP2024534517 A JP 2024534517A JP 2024517482 A JP2024517482 A JP 2024517482A JP 2024517482 A JP2024517482 A JP 2024517482A JP 2024534517 A JP2024534517 A JP 2024534517A
- Authority
- JP
- Japan
- Prior art keywords
- degrees
- compound
- radiation
- cancer
- xrpd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163246451P | 2021-09-21 | 2021-09-21 | |
| US63/246,451 | 2021-09-21 | ||
| PCT/US2022/044232 WO2023049168A1 (en) | 2021-09-21 | 2022-09-21 | Polymorphs as erbb inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024534517A true JP2024534517A (ja) | 2024-09-20 |
| JP2024534517A5 JP2024534517A5 (https=) | 2025-09-30 |
Family
ID=83691602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024517482A Pending JP2024534517A (ja) | 2021-09-21 | 2022-09-21 | Ｅｒｂｂ阻害剤としての多形 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240425492A1 (https=) |
| EP (1) | EP4405350A1 (https=) |
| JP (1) | JP2024534517A (https=) |
| KR (1) | KR20240099193A9 (https=) |
| CN (1) | CN119110799A (https=) |
| AU (1) | AU2022352658A1 (https=) |
| CA (1) | CA3231697A1 (https=) |
| IL (1) | IL311354A (https=) |
| MX (1) | MX2024003475A (https=) |
| WO (1) | WO2023049168A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020328598A1 (en) | 2019-08-15 | 2022-03-03 | Black Diamond Therapeutics, Inc. | Alkynyl quinazoline compounds |
| CN120769850A (zh) * | 2023-03-02 | 2025-10-10 | 江苏康缘药业股份有限公司 | 一种炔基取代的喹唑啉化合物的晶型、其制备方法和应用 |
| WO2025038731A1 (en) * | 2023-08-15 | 2025-02-20 | Black Diamond Therapeutics, Inc. | Method of treating cancers with alkyne substituted quinazoline derivatives |
| WO2025137424A1 (en) * | 2023-12-21 | 2025-06-26 | Black Diamond Therapeutics, Inc. | Solid forms of an erbb inhibitor |
| WO2025137421A1 (en) * | 2023-12-21 | 2025-06-26 | Black Diamond Therapeutics, Inc. | Compositions comprising alkyne substituted quinazoline derivatives and related uses |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020328598A1 (en) * | 2019-08-15 | 2022-03-03 | Black Diamond Therapeutics, Inc. | Alkynyl quinazoline compounds |
| US20240075042A1 (en) * | 2020-11-02 | 2024-03-07 | Black Diamond Therapeutics, Inc. | Method of treating cancers with alkyne substituted quinazoline derivatives |
-
2022
- 2022-09-21 CA CA3231697A patent/CA3231697A1/en active Pending
- 2022-09-21 MX MX2024003475A patent/MX2024003475A/es unknown
- 2022-09-21 AU AU2022352658A patent/AU2022352658A1/en active Pending
- 2022-09-21 CN CN202280075401.6A patent/CN119110799A/zh active Pending
- 2022-09-21 WO PCT/US2022/044232 patent/WO2023049168A1/en not_active Ceased
- 2022-09-21 EP EP22789775.8A patent/EP4405350A1/en active Pending
- 2022-09-21 JP JP2024517482A patent/JP2024534517A/ja active Pending
- 2022-09-21 IL IL311354A patent/IL311354A/en unknown
- 2022-09-21 KR KR1020247013097A patent/KR20240099193A9/ko active Pending
- 2022-09-21 US US18/693,733 patent/US20240425492A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20240099193A9 (ko) | 2025-12-10 |
| AU2022352658A1 (en) | 2024-03-21 |
| EP4405350A1 (en) | 2024-07-31 |
| IL311354A (en) | 2024-05-01 |
| US20240425492A1 (en) | 2024-12-26 |
| KR20240099193A (ko) | 2024-06-28 |
| CA3231697A1 (en) | 2023-03-30 |
| MX2024003475A (es) | 2024-04-05 |
| CN119110799A (zh) | 2024-12-10 |
| WO2023049168A1 (en) | 2023-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20250919 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20250919 |