IL311354A - polymorphs as ERBB inhibitors - Google Patents

polymorphs as ERBB inhibitors

Info

Publication number
IL311354A
IL311354A IL311354A IL31135424A IL311354A IL 311354 A IL311354 A IL 311354A IL 311354 A IL311354 A IL 311354A IL 31135424 A IL31135424 A IL 31135424A IL 311354 A IL311354 A IL 311354A
Authority
IL
Israel
Prior art keywords
polymorphs
erbb inhibitors
erbb
inhibitors
Prior art date
Application number
IL311354A
Other languages
English (en)
Hebrew (he)
Inventor
Wu-Yan Zhang
Reza Foroughi
Siyi Jiang
Meiqi Li
Juanjuan Shi
Original Assignee
Black Diamond Therapeutics Inc
Zhang wu yan
Reza Foroughi
Siyi Jiang
Meiqi Li
Juanjuan Shi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Black Diamond Therapeutics Inc, Zhang wu yan, Reza Foroughi, Siyi Jiang, Meiqi Li, Juanjuan Shi filed Critical Black Diamond Therapeutics Inc
Publication of IL311354A publication Critical patent/IL311354A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL311354A 2021-09-21 2022-09-21 polymorphs as ERBB inhibitors IL311354A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163246451P 2021-09-21 2021-09-21
PCT/US2022/044232 WO2023049168A1 (en) 2021-09-21 2022-09-21 Polymorphs as erbb inhibitors

Publications (1)

Publication Number Publication Date
IL311354A true IL311354A (en) 2024-05-01

Family

ID=83691602

Family Applications (1)

Application Number Title Priority Date Filing Date
IL311354A IL311354A (en) 2021-09-21 2022-09-21 polymorphs as ERBB inhibitors

Country Status (10)

Country Link
US (1) US20240425492A1 (https=)
EP (1) EP4405350A1 (https=)
JP (1) JP2024534517A (https=)
KR (1) KR20240099193A9 (https=)
CN (1) CN119110799A (https=)
AU (1) AU2022352658A1 (https=)
CA (1) CA3231697A1 (https=)
IL (1) IL311354A (https=)
MX (1) MX2024003475A (https=)
WO (1) WO2023049168A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020328598A1 (en) 2019-08-15 2022-03-03 Black Diamond Therapeutics, Inc. Alkynyl quinazoline compounds
CN120769850A (zh) * 2023-03-02 2025-10-10 江苏康缘药业股份有限公司 一种炔基取代的喹唑啉化合物的晶型、其制备方法和应用
WO2025038731A1 (en) * 2023-08-15 2025-02-20 Black Diamond Therapeutics, Inc. Method of treating cancers with alkyne substituted quinazoline derivatives
WO2025137424A1 (en) * 2023-12-21 2025-06-26 Black Diamond Therapeutics, Inc. Solid forms of an erbb inhibitor
WO2025137421A1 (en) * 2023-12-21 2025-06-26 Black Diamond Therapeutics, Inc. Compositions comprising alkyne substituted quinazoline derivatives and related uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020328598A1 (en) * 2019-08-15 2022-03-03 Black Diamond Therapeutics, Inc. Alkynyl quinazoline compounds
US20240075042A1 (en) * 2020-11-02 2024-03-07 Black Diamond Therapeutics, Inc. Method of treating cancers with alkyne substituted quinazoline derivatives

Also Published As

Publication number Publication date
KR20240099193A9 (ko) 2025-12-10
AU2022352658A1 (en) 2024-03-21
EP4405350A1 (en) 2024-07-31
US20240425492A1 (en) 2024-12-26
JP2024534517A (ja) 2024-09-20
KR20240099193A (ko) 2024-06-28
CA3231697A1 (en) 2023-03-30
MX2024003475A (es) 2024-04-05
CN119110799A (zh) 2024-12-10
WO2023049168A1 (en) 2023-03-30

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