MX2024003475A - Polimorfos como inhibidores de erbb. - Google Patents

Polimorfos como inhibidores de erbb.

Info

Publication number
MX2024003475A
MX2024003475A MX2024003475A MX2024003475A MX2024003475A MX 2024003475 A MX2024003475 A MX 2024003475A MX 2024003475 A MX2024003475 A MX 2024003475A MX 2024003475 A MX2024003475 A MX 2024003475A MX 2024003475 A MX2024003475 A MX 2024003475A
Authority
MX
Mexico
Prior art keywords
polymorphs
erbb inhibitors
morphic forms
present disclosure
morphic
Prior art date
Application number
MX2024003475A
Other languages
English (en)
Spanish (es)
Inventor
Siyi Jiang
Wu- Yan ZHANG
Reza Foroughi
Meiqi Li
Juanjuan Shi
Original Assignee
Black Diamond Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Black Diamond Therapeutics Inc filed Critical Black Diamond Therapeutics Inc
Publication of MX2024003475A publication Critical patent/MX2024003475A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2024003475A 2021-09-21 2022-09-21 Polimorfos como inhibidores de erbb. MX2024003475A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163246451P 2021-09-21 2021-09-21
PCT/US2022/044232 WO2023049168A1 (en) 2021-09-21 2022-09-21 Polymorphs as erbb inhibitors

Publications (1)

Publication Number Publication Date
MX2024003475A true MX2024003475A (es) 2024-04-05

Family

ID=83691602

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2024003475A MX2024003475A (es) 2021-09-21 2022-09-21 Polimorfos como inhibidores de erbb.

Country Status (10)

Country Link
US (1) US20240425492A1 (https=)
EP (1) EP4405350A1 (https=)
JP (1) JP2024534517A (https=)
KR (1) KR20240099193A9 (https=)
CN (1) CN119110799A (https=)
AU (1) AU2022352658A1 (https=)
CA (1) CA3231697A1 (https=)
IL (1) IL311354A (https=)
MX (1) MX2024003475A (https=)
WO (1) WO2023049168A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020328598A1 (en) 2019-08-15 2022-03-03 Black Diamond Therapeutics, Inc. Alkynyl quinazoline compounds
CN120769850A (zh) * 2023-03-02 2025-10-10 江苏康缘药业股份有限公司 一种炔基取代的喹唑啉化合物的晶型、其制备方法和应用
WO2025038731A1 (en) * 2023-08-15 2025-02-20 Black Diamond Therapeutics, Inc. Method of treating cancers with alkyne substituted quinazoline derivatives
WO2025137424A1 (en) * 2023-12-21 2025-06-26 Black Diamond Therapeutics, Inc. Solid forms of an erbb inhibitor
WO2025137421A1 (en) * 2023-12-21 2025-06-26 Black Diamond Therapeutics, Inc. Compositions comprising alkyne substituted quinazoline derivatives and related uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020328598A1 (en) * 2019-08-15 2022-03-03 Black Diamond Therapeutics, Inc. Alkynyl quinazoline compounds
US20240075042A1 (en) * 2020-11-02 2024-03-07 Black Diamond Therapeutics, Inc. Method of treating cancers with alkyne substituted quinazoline derivatives

Also Published As

Publication number Publication date
KR20240099193A9 (ko) 2025-12-10
AU2022352658A1 (en) 2024-03-21
EP4405350A1 (en) 2024-07-31
IL311354A (en) 2024-05-01
US20240425492A1 (en) 2024-12-26
JP2024534517A (ja) 2024-09-20
KR20240099193A (ko) 2024-06-28
CA3231697A1 (en) 2023-03-30
CN119110799A (zh) 2024-12-10
WO2023049168A1 (en) 2023-03-30

Similar Documents

Publication Publication Date Title
MX2024003475A (es) Polimorfos como inhibidores de erbb.
CR20220354A (es) Inhibidores de egfr
MX2023010411A (es) Inhibidores de erbb/btk.
MX2025002170A (es) Inhibidores de kras g12c
ZA202110422B (en) Heterocyclic compounds, preparation methods and uses thereof
MX2024001893A (es) Compuestos heterociclicos y metodos de uso.
MX2023012726A (es) Compuestos heterociclicos y metodos de uso.
MX2023008954A (es) Inhibidores de los receptores erbb.
MX2023000025A (es) Inhibidores de la quinasa progenitora hematopoyética 1 y usos de estos.
MX2023000333A (es) Sales y formas de un inhibidor wee1.
MX2025001648A (es) Inhibidores del oncogen homologo del virus de sarcoma de rata kirsten (kras)
MX2024000230A (es) Inhibidores de cdk2.
MX2025015502A (es) Inhibidores del oncogén de sarcoma de rata de kirsten (kras)
MX2026003002A (es) Inhibidores de kras
MX2020010181A (es) Compuestos de piperidina como inhibidores covalentes de menina.
PH12021553233A1 (en) Imidazopyrimidines as eed inhibitors and the use thereof
GEP20115304B (en) PYRIDOPYRIMIDINONE INHIBITORS OF PI3Kα
MX2020008678A (es) Metodos de uso para derivados de benzotriazol trisustituidos.
MX2025001982A (es) Inhibidores de kif18a y usos de estos
CR20240014A (es) Pirimidinil-pirazoles sustituidos como inhibidores de cdk2
SA521420951B1 (ar) مركبات ترايازول تعمل كمثبطات للجليكولات أوكسيداز
ZA202006071B (en) Antiproliferation compounds and uses thereof
MX2024008868A (es) Inhibidores de la apolipoproteína l1 (apol1) y métodos de uso.
MX2024013095A (es) Compuestos inhibidores de fgfr2
PH12022551282A1 (en) Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use