JP2024534169A5 - - Google Patents
Info
- Publication number
- JP2024534169A5 JP2024534169A5 JP2024513142A JP2024513142A JP2024534169A5 JP 2024534169 A5 JP2024534169 A5 JP 2024534169A5 JP 2024513142 A JP2024513142 A JP 2024513142A JP 2024513142 A JP2024513142 A JP 2024513142A JP 2024534169 A5 JP2024534169 A5 JP 2024534169A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrazole
- amino
- pyrimidine
- pyridine
- cyclopropylsulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163237647P | 2021-08-27 | 2021-08-27 | |
| US63/237,647 | 2021-08-27 | ||
| PCT/KR2022/012696 WO2023027518A1 (en) | 2021-08-27 | 2022-08-25 | Substituted aminopyridine compounds as egfr inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024534169A JP2024534169A (ja) | 2024-09-18 |
| JP2024534169A5 true JP2024534169A5 (https=) | 2025-07-31 |
Family
ID=85321881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024513142A Pending JP2024534169A (ja) | 2021-08-27 | 2022-08-25 | Ｅｇｆｒ阻害剤としての置換アミノピリジン化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11981658B2 (https=) |
| EP (1) | EP4392415A4 (https=) |
| JP (1) | JP2024534169A (https=) |
| KR (1) | KR20240052797A (https=) |
| CN (1) | CN117980297A (https=) |
| AR (1) | AR126892A1 (https=) |
| TW (1) | TW202317106A (https=) |
| WO (1) | WO2023027518A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024188338A1 (zh) * | 2023-03-16 | 2024-09-19 | 微境生物医药科技(上海)有限公司 | Kif18a抑制剂 |
| AR132866A1 (es) * | 2023-06-09 | 2025-08-06 | Yuhan Corp | Derivados de pirimidina / piridina o sales de los mismos y composiciones farmacéuticas que los comprenden |
| CN118955498A (zh) * | 2024-07-25 | 2024-11-15 | 浙江大学 | 一种靶向Tau蛋白的新型PET显像剂及其制备方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002092573A2 (en) | 2001-05-16 | 2002-11-21 | Vertex Pharmaceuticals Incorporated | Heterocyclic substituted pyrazoles as inhibitors of src and other protein kinases |
| MXPA05007503A (es) | 2003-01-17 | 2005-09-21 | Warner Lambert Co | Heterociclicos 2-aminopiridina sustituidos como inhibidores de proliferacion celular. |
| CA2561831A1 (en) | 2004-04-13 | 2005-12-22 | Icagen, Inc. | Polycyclic pyrazines as potassium ion channel modulators |
| AU2005233642A1 (en) | 2004-04-13 | 2005-10-27 | Astellas Pharma Inc. | Polycyclic pyridines as potassium ion channel modulators |
| CA2561895A1 (en) | 2004-04-13 | 2005-10-27 | Icagen, Inc. | Polycyclic pyrimidines as potassium ion channel modulators |
| WO2006106721A1 (ja) * | 2005-03-30 | 2006-10-12 | Shionogi & Co., Ltd. | チロシンキナーゼ阻害作用を有するピリミジン誘導体 |
| GB0719644D0 (en) | 2007-10-05 | 2007-11-14 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| TWI552752B (zh) * | 2007-10-19 | 2016-10-11 | 賽基艾維洛米斯研究股份有限公司 | 雜芳基化合物及其用途 |
| US7989465B2 (en) * | 2007-10-19 | 2011-08-02 | Avila Therapeutics, Inc. | 4,6-disubstituted pyrimidines useful as kinase inhibitors |
| WO2013169401A1 (en) * | 2012-05-05 | 2013-11-14 | Ariad Pharmaceuticals, Inc. | Compounds for inhibiting cell proliferation in egfr-driven cancers |
| EP2863914B1 (en) | 2012-06-20 | 2018-10-03 | Merck Sharp & Dohme Corp. | Pyrazolyl derivatives as syk inhibitors |
| WO2014081718A1 (en) * | 2012-11-20 | 2014-05-30 | Genentech, Inc. | Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants |
| JP6523251B2 (ja) | 2013-05-01 | 2019-05-29 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｃ−結合ヘテロシクロアルキル置換ピリミジン類及びそれらの用途 |
| CN104761544B (zh) * | 2014-01-03 | 2019-03-15 | 北京轩义医药科技有限公司 | Egfr酪氨酸激酶的临床重要突变体的选择性抑制剂 |
| JP6468611B2 (ja) * | 2014-05-13 | 2019-02-13 | アリアド ファーマシューティカルズ， インコーポレイテッド | キナーゼ阻害のためのヘテロアリール化合物 |
| EP3778584A1 (en) * | 2014-06-19 | 2021-02-17 | ARIAD Pharmaceuticals, Inc. | Production process of 2-chloro-4-heteroaryl-pyrimidine derivatives |
| CN106588885B (zh) | 2016-11-10 | 2019-03-19 | 浙江大学 | 2-取代芳环-嘧啶类衍生物及制备和应用 |
| WO2019126731A1 (en) * | 2017-12-22 | 2019-06-27 | Petra Pharma Corporation | Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors |
| WO2019222538A1 (en) | 2018-05-16 | 2019-11-21 | The University Of North Carolina At Chapel Hill | Aminopyrimidines and aminopyridines as mertk inhibitors and their application in cancer treatment |
| KR102297587B1 (ko) * | 2018-08-07 | 2021-09-06 | 재단법인 대구경북첨단의료산업진흥재단 | 치환된 n-헤테로아릴 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| KR20210125558A (ko) | 2019-04-02 | 2021-10-18 | 하이노바 파마슈티컬스 인코포레이티드 | 방향족 아민계 화합물 및 이의 ar 및 brd4 이중 억제제 및 조절제의 제조에서의 용도 |
| TW202112767A (zh) | 2019-06-17 | 2021-04-01 | 美商佩特拉製藥公司 | 作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物 |
| WO2020259683A1 (zh) * | 2019-06-28 | 2020-12-30 | 成都赜灵生物医药科技有限公司 | 2，4-二取代嘧啶衍生物及其制备方法和用途 |
| WO2021097326A1 (en) | 2019-11-15 | 2021-05-20 | The University Of North Carolina At Chapel Hill | Aryl aminopyrimidines as dual mertk and tyro3 inhibitors and methods thereof |
-
2022
- 2022-08-24 TW TW111131849A patent/TW202317106A/zh unknown
- 2022-08-25 WO PCT/KR2022/012696 patent/WO2023027518A1/en not_active Ceased
- 2022-08-25 JP JP2024513142A patent/JP2024534169A/ja active Pending
- 2022-08-25 KR KR1020247009721A patent/KR20240052797A/ko active Pending
- 2022-08-25 CN CN202280062421.XA patent/CN117980297A/zh active Pending
- 2022-08-25 EP EP22861726.2A patent/EP4392415A4/en active Pending
- 2022-08-26 AR ARP220102310A patent/AR126892A1/es unknown
- 2022-08-26 US US17/822,450 patent/US11981658B2/en active Active
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