JP2024534169A5 - - Google Patents
Info
- Publication number
- JP2024534169A5 JP2024534169A5 JP2024513142A JP2024513142A JP2024534169A5 JP 2024534169 A5 JP2024534169 A5 JP 2024534169A5 JP 2024513142 A JP2024513142 A JP 2024513142A JP 2024513142 A JP2024513142 A JP 2024513142A JP 2024534169 A5 JP2024534169 A5 JP 2024534169A5
- Authority
- JP
- Japan
- Prior art keywords
- pyrazole
- amino
- pyrimidine
- pyridine
- cyclopropylsulfonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163237647P | 2021-08-27 | 2021-08-27 | |
| US63/237,647 | 2021-08-27 | ||
| PCT/KR2022/012696 WO2023027518A1 (en) | 2021-08-27 | 2022-08-25 | Substituted aminopyridine compounds as egfr inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024534169A JP2024534169A (ja) | 2024-09-18 |
| JP2024534169A5 true JP2024534169A5 (enExample) | 2025-07-31 |
| JP7894442B2 JP7894442B2 (ja) | 2026-07-23 |
Family
ID=85321881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024513142A Active JP7894442B2 (ja) | 2021-08-27 | 2022-08-25 | Ｅｇｆｒ阻害剤としての置換アミノピリジン化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11981658B2 (enExample) |
| EP (1) | EP4392415A4 (enExample) |
| JP (1) | JP7894442B2 (enExample) |
| KR (1) | KR20240052797A (enExample) |
| CN (1) | CN117980297A (enExample) |
| AR (1) | AR126892A1 (enExample) |
| TW (1) | TW202317106A (enExample) |
| WO (1) | WO2023027518A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024188338A1 (zh) * | 2023-03-16 | 2024-09-19 | 微境生物医药科技(上海)有限公司 | Kif18a抑制剂 |
| TW202513556A (zh) * | 2023-06-09 | 2025-04-01 | 南韓商柳韓洋行 | 嘧啶/吡啶衍生物或其鹽及以此為成分之藥物組成物 |
| CN118955498A (zh) * | 2024-07-25 | 2024-11-15 | 浙江大学 | 一种靶向Tau蛋白的新型PET显像剂及其制备方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4316893B2 (ja) | 2001-05-16 | 2009-08-19 | バーテックス ファーマシューティカルズ インコーポレイテッド | Ｓｒｃおよび他のプロテインキナーゼのインヒビター |
| EP1590341B1 (en) * | 2003-01-17 | 2009-06-17 | Warner-Lambert Company LLC | 2-aminopyridine substituted heterocycles as inhibitors of cellular proliferation |
| US7642354B2 (en) | 2004-04-13 | 2010-01-05 | Icagen, Inc. | Polycyclic pyrazines as potassium ion channel modulators |
| EP1737852A2 (en) | 2004-04-13 | 2007-01-03 | Icagen, Inc. | Polycyclic pyridines as potassium ion channel modulators |
| JP2007532669A (ja) | 2004-04-13 | 2007-11-15 | イカジェン インコーポレイテッド | カリウムイオンチャネル調節剤としての多環式ピリミジン |
| WO2006106721A1 (ja) | 2005-03-30 | 2006-10-12 | Shionogi & Co., Ltd. | チロシンキナーゼ阻害作用を有するピリミジン誘導体 |
| GB0719644D0 (en) | 2007-10-05 | 2007-11-14 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| US7989465B2 (en) * | 2007-10-19 | 2011-08-02 | Avila Therapeutics, Inc. | 4,6-disubstituted pyrimidines useful as kinase inhibitors |
| JP5600063B2 (ja) * | 2007-10-19 | 2014-10-01 | セルジーン アビロミクス リサーチ， インコーポレイテッド | ヘテロアリール化合物およびその使用 |
| JP6469567B2 (ja) | 2012-05-05 | 2019-02-13 | アリアド・ファーマシューティカルズ・インコーポレイテッド | Ｅｇｆｒ発動性がんの細胞増殖阻害用化合物 |
| WO2013192125A1 (en) | 2012-06-20 | 2013-12-27 | Merck Sharp & Dohme Corp. | Pyrazolyl derivatives as syk inhibitors |
| EP3181564B1 (en) | 2012-11-20 | 2019-09-18 | H. Hoffnabb-La Roche Ag | Aminopyrimidine compounds as inhibitors of t790m containing egfr mutants |
| RU2015147601A (ru) | 2013-05-01 | 2017-06-05 | Ф. Хоффманн-Ля Рош Аг | С-связанные гетероциклоалкилзамещенные пиримидины и их применения |
| CN104761544B (zh) * | 2014-01-03 | 2019-03-15 | 北京轩义医药科技有限公司 | Egfr酪氨酸激酶的临床重要突变体的选择性抑制剂 |
| US20170166598A1 (en) | 2014-05-13 | 2017-06-15 | Ariad Pharmaceuticals, Inc. | Heteroaryl compounds for kinase inhibition |
| CA2949793C (en) * | 2014-06-19 | 2024-02-27 | Ariad Pharmaceuticals, Inc. | Heteroaryl compounds for kinase inhibition |
| CN106588885B (zh) | 2016-11-10 | 2019-03-19 | 浙江大学 | 2-取代芳环-嘧啶类衍生物及制备和应用 |
| WO2019126731A1 (en) * | 2017-12-22 | 2019-06-27 | Petra Pharma Corporation | Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors |
| WO2019222538A1 (en) | 2018-05-16 | 2019-11-21 | The University Of North Carolina At Chapel Hill | Aminopyrimidines and aminopyridines as mertk inhibitors and their application in cancer treatment |
| KR102297587B1 (ko) * | 2018-08-07 | 2021-09-06 | 재단법인 대구경북첨단의료산업진흥재단 | 치환된 n-헤테로아릴 유도체, 이의 제조방법 및 이를 유효성분으로 포함하는 암의 예방 또는 치료용 약학적 조성물 |
| US20220177459A1 (en) | 2019-04-02 | 2022-06-09 | Hinova Pharmaceuticals Inc. | Aromatic amine compound and use thereof in preparation of ar and brd4 dual inhibitors and regulators |
| TW202112767A (zh) | 2019-06-17 | 2021-04-01 | 美商佩特拉製藥公司 | 作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物 |
| HRP20241633T1 (hr) * | 2019-06-28 | 2025-02-14 | Chengdu Zenitar Biomedical Technology Co., Ltd. | 2,4-disupstituirani derivat pirimidina, postupak njegove pripreme i njegova uporaba |
| JP2023502969A (ja) | 2019-11-15 | 2023-01-26 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | ＭｅｒＴＫおよびＴＹＲＯ３の二重阻害剤としてのアリールアミノピリミジンおよびその方法 |
-
2022
- 2022-08-24 TW TW111131849A patent/TW202317106A/zh unknown
- 2022-08-25 EP EP22861726.2A patent/EP4392415A4/en active Pending
- 2022-08-25 KR KR1020247009721A patent/KR20240052797A/ko active Pending
- 2022-08-25 CN CN202280062421.XA patent/CN117980297A/zh active Pending
- 2022-08-25 JP JP2024513142A patent/JP7894442B2/ja active Active
- 2022-08-25 WO PCT/KR2022/012696 patent/WO2023027518A1/en not_active Ceased
- 2022-08-26 US US17/822,450 patent/US11981658B2/en active Active
- 2022-08-26 AR ARP220102310A patent/AR126892A1/es unknown
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