JP2024532734A5 - - Google Patents

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Publication number
JP2024532734A5
JP2024532734A5 JP2024507879A JP2024507879A JP2024532734A5 JP 2024532734 A5 JP2024532734 A5 JP 2024532734A5 JP 2024507879 A JP2024507879 A JP 2024507879A JP 2024507879 A JP2024507879 A JP 2024507879A JP 2024532734 A5 JP2024532734 A5 JP 2024532734A5
Authority
JP
Japan
Prior art keywords
fluoro
pyrrolidine
methoxy
pyrimidine
fluorotetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024507879A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024532734A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/039971 external-priority patent/WO2023018812A1/en
Publication of JP2024532734A publication Critical patent/JP2024532734A/ja
Publication of JP2024532734A5 publication Critical patent/JP2024532734A5/ja
Pending legal-status Critical Current

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JP2024507879A 2021-08-10 2022-08-10 複素環式化合物及び使用方法 Pending JP2024532734A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163231543P 2021-08-10 2021-08-10
US63/231,543 2021-08-10
US202163289579P 2021-12-14 2021-12-14
US63/289,579 2021-12-14
PCT/US2022/039971 WO2023018812A1 (en) 2021-08-10 2022-08-10 Heterocyclic compounds and methods of use

Publications (2)

Publication Number Publication Date
JP2024532734A JP2024532734A (ja) 2024-09-10
JP2024532734A5 true JP2024532734A5 (https=) 2025-08-19

Family

ID=85201014

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024507879A Pending JP2024532734A (ja) 2021-08-10 2022-08-10 複素環式化合物及び使用方法

Country Status (7)

Country Link
EP (1) EP4384160A4 (https=)
JP (1) JP2024532734A (https=)
AU (1) AU2022325771A1 (https=)
CA (1) CA3228310A1 (https=)
MX (1) MX2024001893A (https=)
TW (1) TW202330529A (https=)
WO (1) WO2023018812A1 (https=)

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CA3247639A1 (en) 2022-05-06 2023-11-09 PAQ Therapeutics Inc. CHIMERAS TARGET KRAS-G12D PROTEOLYSIS
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WO2024008068A1 (en) * 2022-07-04 2024-01-11 Jacobio Pharmaceuticals Co., Ltd. K-ras mutant protein inhibitors
WO2024012519A1 (zh) * 2022-07-13 2024-01-18 北京华森英诺生物科技有限公司 Pan-kras抑制剂
WO2024041606A1 (zh) * 2022-08-24 2024-02-29 泰励生物科技(上海)有限公司 具有抗kras突变肿瘤活性的化合物
TW202430179A (zh) 2022-11-21 2024-08-01 美商樹線生物科學公司 螺環二氫哌喃并嘧啶KRas抑制劑
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CN121100123A (zh) 2023-04-14 2025-12-09 锐新医药公司 Ras抑制剂的结晶形式
CN121464140A (zh) 2023-04-14 2026-02-03 锐新医药公司 Ras抑制剂的结晶形式、含有其的组合物及其使用方法
TW202508595A (zh) 2023-05-04 2025-03-01 美商銳新醫藥公司 用於ras相關疾病或病症之組合療法
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TW202528315A (zh) 2023-09-21 2025-07-16 美商樹線生物科學公司 螺環二氫哌喃并吡啶KRas抑制劑
CN121941690A (zh) 2023-10-03 2026-04-28 Paq医疗公司 Kras蛋白水解靶向嵌合体
TW202529804A (zh) 2023-10-06 2025-08-01 美商安進公司 用於癌症治療的組合療法
US20250114346A1 (en) 2023-10-09 2025-04-10 Incyte Corporation Combination therapy using a kras g12d inhibitor and pd-1 inhibitor or pd-l1 inhibitor
US20250114339A1 (en) 2023-10-09 2025-04-10 Incyte Corporation Combination therapy comprising a kras g12d inhibitor and an egfr inhibitor
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TW202602882A (zh) * 2024-03-14 2026-01-16 美商安進公司 作為kras調節劑的大環化合物及其用途
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CN117222650A (zh) * 2021-04-30 2023-12-12 劲方医药科技(上海)有限公司 吡啶或嘧啶并环类化合物,其制法与医药上的用途
BR112023024906A2 (pt) * 2021-05-28 2024-02-15 Redx Pharma Plc Compostos

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