JP2024528982A5 - - Google Patents
Info
- Publication number
- JP2024528982A5 JP2024528982A5 JP2024506658A JP2024506658A JP2024528982A5 JP 2024528982 A5 JP2024528982 A5 JP 2024528982A5 JP 2024506658 A JP2024506658 A JP 2024506658A JP 2024506658 A JP2024506658 A JP 2024506658A JP 2024528982 A5 JP2024528982 A5 JP 2024528982A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- branched
- haloalkyl
- hydroxyalkyl
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163229882P | 2021-08-05 | 2021-08-05 | |
| US63/229,882 | 2021-08-05 | ||
| PCT/US2022/039529 WO2023014943A1 (en) | 2021-08-05 | 2022-08-05 | Methods of treating migraine with mnk inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024528982A JP2024528982A (ja) | 2024-08-01 |
| JP2024528982A5 true JP2024528982A5 (https=) | 2025-08-13 |
Family
ID=85154787
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024506658A Pending JP2024528982A (ja) | 2021-08-05 | 2022-08-05 | Ｍｎｋ阻害剤による片頭痛の治療方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250205244A1 (https=) |
| EP (1) | EP4380566A4 (https=) |
| JP (1) | JP2024528982A (https=) |
| KR (1) | KR20240055743A (https=) |
| CN (1) | CN118076354A (https=) |
| AU (1) | AU2022324472A1 (https=) |
| CA (1) | CA3228265A1 (https=) |
| IL (1) | IL310590A (https=) |
| MX (1) | MX2024001560A (https=) |
| WO (1) | WO2023014943A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4646266A1 (en) * | 2023-01-04 | 2025-11-12 | 4E Therapeutics, Inc. | Solid state forms of mnk inhibitors |
| CN116735759B (zh) * | 2023-08-14 | 2023-11-07 | 南京威凯尔生物医药科技有限公司 | 一种高效液相色谱法检测乌布吉泮中间体及其对映体杂质的方法 |
| WO2026006417A1 (en) * | 2024-06-26 | 2026-01-02 | 4E Therapeutics, Inc. | Formulations of mnk inhibitors |
| WO2026006453A1 (en) * | 2024-06-26 | 2026-01-02 | 4E Therapeutics, Inc. | Solid dispersion formulations of mnk inhibitors |
| WO2026006442A1 (en) * | 2024-06-26 | 2026-01-02 | 4E Therapeutics, Inc. | Deuterated mnk inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080039450A1 (en) * | 2006-06-22 | 2008-02-14 | Jensen Annika J | Compounds |
| US10280168B2 (en) * | 2012-03-30 | 2019-05-07 | Agency For Science, Technology And Research | Bicyclic heteroaryl derivatives as MNK1 and MNK2 modulators and uses thereof |
| TWI713455B (zh) * | 2014-06-25 | 2020-12-21 | 美商伊凡克特治療公司 | ＭｎＫ抑制劑及其相關方法 |
| TW201831479A (zh) * | 2017-01-20 | 2018-09-01 | 德商拜耳製藥公司 | 經取代二氫咪唑并吡啶二酮 |
| US20190388425A1 (en) * | 2017-01-20 | 2019-12-26 | Bayer Pharma Aktiengesellschaft | Substituted imidazopyridinpyrimidines |
| EP3972593B1 (en) * | 2019-05-23 | 2025-07-02 | Board of Regents, The University of Texas System | Inhibitor of mnk for the treatment of neuropathic pain |
-
2022
- 2022-08-05 EP EP22853939.1A patent/EP4380566A4/en active Pending
- 2022-08-05 CA CA3228265A patent/CA3228265A1/en active Pending
- 2022-08-05 IL IL310590A patent/IL310590A/en unknown
- 2022-08-05 WO PCT/US2022/039529 patent/WO2023014943A1/en not_active Ceased
- 2022-08-05 KR KR1020247007155A patent/KR20240055743A/ko active Pending
- 2022-08-05 AU AU2022324472A patent/AU2022324472A1/en active Pending
- 2022-08-05 MX MX2024001560A patent/MX2024001560A/es unknown
- 2022-08-05 CN CN202280062076.XA patent/CN118076354A/zh active Pending
- 2022-08-05 US US18/294,823 patent/US20250205244A1/en active Pending
- 2022-08-05 JP JP2024506658A patent/JP2024528982A/ja active Pending
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