JP2024527313A5 - - Google Patents
Info
- Publication number
- JP2024527313A5 JP2024527313A5 JP2023580435A JP2023580435A JP2024527313A5 JP 2024527313 A5 JP2024527313 A5 JP 2024527313A5 JP 2023580435 A JP2023580435 A JP 2023580435A JP 2023580435 A JP2023580435 A JP 2023580435A JP 2024527313 A5 JP2024527313 A5 JP 2024527313A5
- Authority
- JP
- Japan
- Prior art keywords
- raav
- vector
- sequence
- pharmaceutical composition
- capsid protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163215833P | 2021-06-28 | 2021-06-28 | |
| US63/215,833 | 2021-06-28 | ||
| US202263267440P | 2022-02-02 | 2022-02-02 | |
| US63/267,440 | 2022-02-02 | ||
| US202263342240P | 2022-05-16 | 2022-05-16 | |
| US63/342,240 | 2022-05-16 | ||
| PCT/US2022/035091 WO2023278305A1 (en) | 2021-06-28 | 2022-06-27 | Methods and compositions for tau reduction gene therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024527313A JP2024527313A (ja) | 2024-07-24 |
| JP2024527313A5 true JP2024527313A5 (https=) | 2025-06-25 |
Family
ID=82694082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023580435A Pending JP2024527313A (ja) | 2021-06-28 | 2022-06-27 | タウ低減遺伝子療法のための方法および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240269161A1 (https=) |
| EP (1) | EP4362986A1 (https=) |
| JP (1) | JP2024527313A (https=) |
| AU (1) | AU2022301044A1 (https=) |
| CA (1) | CA3223506A1 (https=) |
| WO (1) | WO2023278305A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025027577A1 (en) * | 2023-08-02 | 2025-02-06 | Consejo Nacional De Investigaciones Científicas Y Técnicas (Conicet) | Micrornas designed against the microtubule-associated protein tau for the treatment of tauopathies |
| WO2025122644A1 (en) * | 2023-12-05 | 2025-06-12 | Voyager Therapeutics, Inc. | Compositions and methods for regulating mapt |
| US20250197862A1 (en) * | 2023-12-15 | 2025-06-19 | Genzyme Corporation | ARTIFICIAL microRNAs TARGETING TAU |
| US12551569B2 (en) | 2024-03-31 | 2026-02-17 | Arrowhead Pharmaceuticals, Inc. | RNAi agents for inhibiting expression of microtubule associated protein tau (MAPT), compositions thereof, and methods of use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7056502B2 (en) | 2000-04-28 | 2006-06-06 | The Trustees Of The University Of Pennsylvania | Recombinant aav vectors with AAV5 capsids and AAV5 vectors pseudotyped in heterologous capsids |
| DE10120265A1 (de) | 2001-04-25 | 2002-11-14 | Deutsches Krebsforsch | AAV-Helferplasmide zur Helfervirus-freien Verpackung und Pseudotypisierung von AAV-Vektoren |
| US9434928B2 (en) | 2011-11-23 | 2016-09-06 | Nationwide Children's Hospital, Inc. | Recombinant adeno-associated virus delivery of alpha-sarcoglycan polynucleotides |
| CN112501208A (zh) * | 2017-10-03 | 2021-03-16 | 普利维尔治疗公司 | 用于溶酶体障碍的基因疗法 |
| WO2020210615A1 (en) * | 2019-04-10 | 2020-10-15 | Prevail Therapeutics, Inc. | Gene therapies for lysosomal disorders |
-
2022
- 2022-06-27 JP JP2023580435A patent/JP2024527313A/ja active Pending
- 2022-06-27 US US18/569,019 patent/US20240269161A1/en active Pending
- 2022-06-27 CA CA3223506A patent/CA3223506A1/en active Pending
- 2022-06-27 WO PCT/US2022/035091 patent/WO2023278305A1/en not_active Ceased
- 2022-06-27 AU AU2022301044A patent/AU2022301044A1/en active Pending
- 2022-06-27 EP EP22747202.4A patent/EP4362986A1/en active Pending
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