JP2024526984A5 - - Google Patents
Info
- Publication number
- JP2024526984A5 JP2024526984A5 JP2024504199A JP2024504199A JP2024526984A5 JP 2024526984 A5 JP2024526984 A5 JP 2024526984A5 JP 2024504199 A JP2024504199 A JP 2024504199A JP 2024504199 A JP2024504199 A JP 2024504199A JP 2024526984 A5 JP2024526984 A5 JP 2024526984A5
- Authority
- JP
- Japan
- Prior art keywords
- heterocycloalkyl
- independently selected
- heteroatoms independently
- bond
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163225401P | 2021-07-23 | 2021-07-23 | |
| US63/225,401 | 2021-07-23 | ||
| PCT/US2022/038084 WO2023004163A1 (en) | 2021-07-23 | 2022-07-22 | Bifunctional compounds for degrading btk with enhanced imid activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024526984A JP2024526984A (ja) | 2024-07-19 |
| JP2024526984A5 true JP2024526984A5 (https=) | 2025-07-25 |
Family
ID=82898772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024504199A Pending JP2024526984A (ja) | 2021-07-23 | 2022-07-22 | 増進されたＩＭｉＤ活性を伴ってＢＴＫを分解するための二官能性化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250017922A1 (https=) |
| EP (1) | EP4373493A1 (https=) |
| JP (1) | JP2024526984A (https=) |
| KR (1) | KR20240039001A (https=) |
| CN (1) | CN118019539A (https=) |
| AU (1) | AU2022313210A1 (https=) |
| CA (1) | CA3226590A1 (https=) |
| IL (1) | IL310269A (https=) |
| MX (1) | MX2024000947A (https=) |
| WO (1) | WO2023004163A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021004191A (es) | 2018-10-15 | 2021-05-27 | Nurix Therapeutics Inc | Compuestos bifuncionales para degradar la tirosina cinasa de bruton (btk) mediante la trayectoria de ubiquitina proteosoma. |
| US12582722B2 (en) | 2019-02-13 | 2026-03-24 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading BTK via ubiquitin proteosome pathway |
| WO2021113557A1 (en) | 2019-12-04 | 2021-06-10 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
| JP2024524480A (ja) * | 2021-07-01 | 2024-07-05 | ハンチョウ、ヘルズン、セラピューティクス、カンパニー、リミテッド | ブルトン型チロシンキナーゼ及びその突然変異体の分解剤、組成物並びにそれらの応用 |
| CA3236073A1 (en) | 2021-10-26 | 2023-05-04 | Robert J. Brown | Piperidinylpyrazine-carboxamide compounds for treating and preventing cancer and for degrading btk |
| CN120202200A (zh) * | 2023-06-01 | 2025-06-24 | 标新生物医药科技(上海)有限公司 | 基于氧代异吲哚啉基取代的四氢嘧啶二酮的化合物及其应用 |
| WO2025162210A1 (zh) * | 2024-02-04 | 2025-08-07 | 上海超阳药业有限公司 | 一种具备降解酪氨酸蛋白激酶btk活性的化合物及其制备方法和用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2021004191A (es) | 2018-10-15 | 2021-05-27 | Nurix Therapeutics Inc | Compuestos bifuncionales para degradar la tirosina cinasa de bruton (btk) mediante la trayectoria de ubiquitina proteosoma. |
| WO2021113557A1 (en) | 2019-12-04 | 2021-06-10 | Nurix Therapeutics, Inc. | Bifunctional compounds for degrading btk via ubiquitin proteosome pathway |
-
2022
- 2022-07-22 CN CN202280064042.4A patent/CN118019539A/zh active Pending
- 2022-07-22 WO PCT/US2022/038084 patent/WO2023004163A1/en not_active Ceased
- 2022-07-22 KR KR1020247006052A patent/KR20240039001A/ko active Pending
- 2022-07-22 CA CA3226590A patent/CA3226590A1/en active Pending
- 2022-07-22 IL IL310269A patent/IL310269A/en unknown
- 2022-07-22 AU AU2022313210A patent/AU2022313210A1/en active Pending
- 2022-07-22 MX MX2024000947A patent/MX2024000947A/es unknown
- 2022-07-22 US US18/290,920 patent/US20250017922A1/en active Pending
- 2022-07-22 JP JP2024504199A patent/JP2024526984A/ja active Pending
- 2022-07-22 EP EP22754662.9A patent/EP4373493A1/en active Pending
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