JP2024522642A5 - - Google Patents
Info
- Publication number
- JP2024522642A5 JP2024522642A5 JP2023576018A JP2023576018A JP2024522642A5 JP 2024522642 A5 JP2024522642 A5 JP 2024522642A5 JP 2023576018 A JP2023576018 A JP 2023576018A JP 2023576018 A JP2023576018 A JP 2023576018A JP 2024522642 A5 JP2024522642 A5 JP 2024522642A5
- Authority
- JP
- Japan
- Prior art keywords
- functional
- gulo
- protein
- liver
- liver organoid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163209908P | 2021-06-11 | 2021-06-11 | |
| US63/209,908 | 2021-06-11 | ||
| PCT/US2022/033066 WO2022261471A2 (en) | 2021-06-11 | 2022-06-10 | Liver organoid model for hyperbilirubinemia and methods of making and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024522642A JP2024522642A (ja) | 2024-06-21 |
| JP2024522642A5 true JP2024522642A5 (https=) | 2025-06-23 |
Family
ID=84426428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023576018A Pending JP2024522642A (ja) | 2021-06-11 | 2022-06-10 | 高ビリルビン血症のための肝臓オルガノイドモデル及びその作製方法及び使用方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20240368556A1 (https=) |
| EP (1) | EP4352206A4 (https=) |
| JP (1) | JP2024522642A (https=) |
| WO (1) | WO2022261471A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| SG10201801654RA (en) | 2014-05-28 | 2018-04-27 | Childrens Hospital Med Ct | Methods and systems for converting precursor cells into gastric tissues through directed differentiation |
| EP4553082A3 (en) | 2016-11-04 | 2025-08-20 | Children's Hospital Medical Center | Liver organoid compositions and methods of making and using same |
| JP7248586B2 (ja) | 2017-04-14 | 2023-03-29 | チルドレンズ ホスピタル メディカル センター | 複数ドナー幹細胞組成物およびそれを作製する方法 |
| EP3694603B1 (en) | 2017-10-10 | 2026-04-08 | Children's Hospital Medical Center | Esophageal tissue and/or organoid compositions and methods of making same |
| EP3727394A4 (en) | 2017-12-21 | 2021-09-08 | Children's Hospital Medical Center | DIGITALIZED HUMAN ORGANOIDS AND METHOD OF USING THEREOF |
| EP4678727A3 (en) | 2018-07-26 | 2026-03-11 | Children's Hospital Medical Center | Hepato-biliary-pancreatic tissues and methods of making same |
| CA3112026A1 (en) | 2018-09-12 | 2020-03-19 | Children's Hospital Medical Center | Organoid compositions for the production of hematopoietic stem cells and derivatives thereof |
| US12600943B2 (en) | 2019-02-01 | 2026-04-14 | The University Of Hong Kong | Innervated organoid compositions and methods of making same |
| AU2020283048A1 (en) | 2019-05-31 | 2021-12-23 | Children's Hospital Medical Center | Shaped organoid compositions and methods of making same |
| US12497597B2 (en) | 2019-05-31 | 2025-12-16 | Children's Hospital Medical Center | Methods of generating and expanding hematopoietic stem cells |
| WO2024206911A2 (en) * | 2023-03-30 | 2024-10-03 | Children's Hospital Medical Center | Clinical-grade organoids |
| WO2025231435A1 (en) * | 2024-05-02 | 2025-11-06 | R.P. Scherer Technologies, Llc | Development of human hepatocyte differentiation and detection method using ipscs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3350313B1 (en) * | 2015-09-15 | 2025-11-26 | Agency For Science, Technology And Research (A*star) | Derivation of liver organoids from human pluripotent stem cells |
| WO2018226267A1 (en) * | 2017-06-09 | 2018-12-13 | Children's Hospital Medical Center | Liver organoid compositions and methods of making and using same |
| EP3856204A4 (en) * | 2018-09-27 | 2022-06-29 | Children's Hospital Medical Center | Liver support system comprising liver organoids and methods of making and using same |
| JP7556502B2 (ja) * | 2019-05-09 | 2024-09-26 | フジフィルム セルラー ダイナミクス，インコーポレイテッド | ヘパトサイトの作製方法 |
-
2022
- 2022-06-10 JP JP2023576018A patent/JP2024522642A/ja active Pending
- 2022-06-10 WO PCT/US2022/033066 patent/WO2022261471A2/en not_active Ceased
- 2022-06-10 US US18/568,764 patent/US20240368556A1/en active Pending
- 2022-06-10 EP EP22821137.1A patent/EP4352206A4/en active Pending
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