|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US5585362A
(en)
|
1989-08-22 |
1996-12-17 |
The Regents Of The University Of Michigan |
Adenovirus vectors for gene therapy
|
|
US5350674A
(en)
|
1992-09-04 |
1994-09-27 |
Becton, Dickinson And Company |
Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US5928906A
(en)
|
1996-05-09 |
1999-07-27 |
Sequenom, Inc. |
Process for direct sequencing during template amplification
|
|
PT904392E
(pt)
|
1996-10-17 |
2001-06-29 |
Oxford Biomedica Ltd |
Vectores retrovirais
|
|
GB9720465D0
(en)
|
1997-09-25 |
1997-11-26 |
Oxford Biomedica Ltd |
Dual-virus vectors
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
ES2373406T3
(es)
|
1997-12-22 |
2012-02-03 |
Oxford Biomedica (Uk) Limited |
Vectores basados en el virus de la anemia infecciosa equina (vaie).
|
|
GB9803351D0
(en)
|
1998-02-17 |
1998-04-15 |
Oxford Biomedica Ltd |
Anti-viral vectors
|
|
FR2777909B1
(fr)
|
1998-04-24 |
2002-08-02 |
Pasteur Institut |
Utilisation de sequences d'adn de structure triplex pour le tranfert de sequences de nucleotides dans des cellules, vecteurs recombinants contenant ces sequences triplex
|
|
GB0009760D0
(en)
|
2000-04-19 |
2000-06-07 |
Oxford Biomedica Ltd |
Method
|
|
US9085778B2
(en)
|
2006-05-03 |
2015-07-21 |
VL27, Inc. |
Exosome transfer of nucleic acids to cells
|
|
EP2498823B1
(en)
|
2009-11-13 |
2018-08-29 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Direct protein delivery with engineered microvesicles
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
CN103946952A
(zh)
|
2011-09-16 |
2014-07-23 |
宾夕法尼亚大学董事会 |
用于治疗癌症的rna改造的t细胞
|
|
ES2642276T3
(es)
*
|
2011-09-29 |
2017-11-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Vectores lentivirales pseudotipados con glicoproteínas de envoltura BaEV mutantes
|
|
EP2844746A4
(en)
|
2012-03-26 |
2016-07-20 |
Univ California |
PSEUDOTYPIZED LENTIVIRES WITH NIPAH VIRUS COVERS AND METHOD OF USE THEREOF
|
|
CN105051192B
(zh)
|
2012-11-13 |
2020-04-17 |
科迪艾克生物科学公司 |
治疗剂的递送
|
|
EP2990416B1
(en)
|
2014-08-29 |
2018-06-20 |
GEMoaB Monoclonals GmbH |
Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
|
|
WO2016077639A2
(en)
|
2014-11-12 |
2016-05-19 |
VL27, Inc. |
Nanovesicular therapies
|
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
|
US11623950B2
(en)
*
|
2015-07-09 |
2023-04-11 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Lentiviral vector expressing membrane-anchored or secreted antibody
|
|
US20180291080A1
(en)
|
2015-09-28 |
2018-10-11 |
Trustees Of Dartmouth College |
Chimeric antigen receptor, regulatory cells and methods of use
|
|
JP2018534264A
(ja)
|
2015-09-28 |
2018-11-22 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
自己免疫および同種免疫への治療的介入としてのキメラ抗原受容体（ｃａｒ）ｔ細胞
|
|
WO2017068077A1
(en)
|
2015-10-20 |
2017-04-27 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Methods and products for genetic engineering
|
|
US11903974B2
(en)
|
2015-11-30 |
2024-02-20 |
Flagship Pioneering Innovations V, Inc. |
Methods and compositions relating to chondrisomes from cultured cells
|
|
CA3017586A1
(en)
|
2016-03-15 |
2017-09-21 |
Codiak Biosciences, Inc. |
Therapeutic membrane vesicles
|
|
EP3235908A1
(en)
|
2016-04-21 |
2017-10-25 |
Ecole Normale Superieure De Lyon |
Methods for selectively modulating the activity of distinct subtypes of cells
|
|
CA3062426A1
(en)
|
2017-05-08 |
2018-11-15 |
Flagship Pioneering Innovations V, Inc. |
Compositions for facilitating membrane fusion and uses thereof
|
|
KR102761791B1
(ko)
|
2017-06-26 |
2025-02-05 |
더 브로드 인스티튜트, 인코퍼레이티드 |
표적화된 핵산 편집을 위한 crispr/cas-아데닌 데아미나아제 기반 조성물, 시스템 및 방법
|
|
WO2019005886A1
(en)
|
2017-06-26 |
2019-01-03 |
The Broad Institute, Inc. |
CRISPR / CAS-CYTIDINE DEAMINASE COMPOSITIONS, SYSTEMS AND METHODS FOR TARGETED EDITING OF NUCLEIC ACIDS
|
|
US20210187018A1
(en)
|
2017-12-07 |
2021-06-24 |
Flagship Pioneering Innovations V, Inc. |
Cytobiologics and therapeutic uses thereof
|
|
WO2019126709A1
(en)
|
2017-12-22 |
2019-06-27 |
The Broad Institute, Inc. |
Cas12b systems, methods, and compositions for targeted dna base editing
|
|
EP3728576A4
(en)
|
2017-12-22 |
2021-11-24 |
The Broad Institute, Inc. |
CAS12B SYSTEMS, METHODS AND COMPOSITIONS FOR SPECIFIC EDITING OF RNA BASES
|
|
US20210079366A1
(en)
|
2017-12-22 |
2021-03-18 |
The Broad Institute, Inc. |
Cas12a systems, methods, and compositions for targeted rna base editing
|
|
WO2019157319A1
(en)
|
2018-02-12 |
2019-08-15 |
Flagship Pioneering Innovations V, Inc. |
Devices and methods for delivering material into a biological tissue or cell
|
|
AU2019222560B2
(en)
|
2018-02-17 |
2025-07-03 |
Flagship Pioneering Innovations V, Inc. |
Compositions and methods for membrane protein delivery
|
|
SG11202011015QA
(en)
|
2018-05-15 |
2020-12-30 |
Flagship Pioneering Innovations V Inc |
Fusosome compositions and uses thereof
|
|
CN112955174A
(zh)
|
2018-07-09 |
2021-06-11 |
旗舰先锋创新V股份有限公司 |
融合剂脂质体组合物和其用途
|
|
WO2020051562A2
(en)
|
2018-09-07 |
2020-03-12 |
Beam Therapeutics Inc. |
Compositions and methods for improving base editing
|
|
AU2019378883A1
(en)
|
2018-11-14 |
2021-06-03 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for T cell delivery
|
|
US20220008557A1
(en)
|
2018-11-14 |
2022-01-13 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for cns delivery
|
|
CN113631718A
(zh)
|
2018-11-14 |
2021-11-09 |
旗舰先锋创新V股份有限公司 |
用于特定隔室货物递送的组合物和方法
|
|
EP3880832A1
(en)
|
2018-11-14 |
2021-09-22 |
Flagship Pioneering Innovations V, Inc. |
Fusosome compositions for hematopoietic stem cell delivery
|
|
WO2020181195A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenine excision
|
|
WO2020181202A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
A:t to t:a base editing through adenine deamination and oxidation
|
|
WO2020181178A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through thymine alkylation
|
|
WO2020181193A1
(en)
|
2019-03-06 |
2020-09-10 |
The Broad Institute, Inc. |
T:a to a:t base editing through adenosine methylation
|
|
WO2020191233A1
(en)
|
2019-03-19 |
2020-09-24 |
The Broad Institute, Inc. |
Methods and compositions for editing nucleotide sequences
|
|
US12473543B2
(en)
|
2019-04-17 |
2025-11-18 |
The Broad Institute, Inc. |
Adenine base editors with reduced off-target effects
|
|
EP4100519A2
(en)
|
2020-02-05 |
2022-12-14 |
The Broad Institute, Inc. |
Adenine base editors and uses thereof
|
|
IL297761A
(en)
|
2020-05-08 |
2022-12-01 |
Broad Inst Inc |
Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence
|
|
CA3193099A1
(en)
|
2020-09-24 |
2022-03-31 |
David R. Liu |
Prime editing guide rnas, compositions thereof, and methods of using the same
|