JP2024521792A - 補体媒介性疾患の治療法 - Google Patents

補体媒介性疾患の治療法 Download PDF

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JP2024521792A
JP2024521792A JP2023572828A JP2023572828A JP2024521792A JP 2024521792 A JP2024521792 A JP 2024521792A JP 2023572828 A JP2023572828 A JP 2023572828A JP 2023572828 A JP2023572828 A JP 2023572828A JP 2024521792 A JP2024521792 A JP 2024521792A
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sirna
antisense strand
nucleotide
strand
sense strand
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JP2024521792A5 (https=
JPWO2022251484A5 (https=
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シャイブラー，ルーカス
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Apellis Pharmaceuticals Inc
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Apellis Pharmaceuticals Inc
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2023572828A 2021-05-26 2022-05-26 補体媒介性疾患の治療法 Pending JP2024521792A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163193573P 2021-05-26 2021-05-26
US63/193,573 2021-05-26
PCT/US2022/031115 WO2022251484A1 (en) 2021-05-26 2022-05-26 Treatment of complement-mediated disorders

Publications (3)

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JP2024521792A true JP2024521792A (ja) 2024-06-04
JP2024521792A5 JP2024521792A5 (https=) 2025-06-02
JPWO2022251484A5 JPWO2022251484A5 (https=) 2025-06-02

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ID=84229204

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JP2023572828A Pending JP2024521792A (ja) 2021-05-26 2022-05-26 補体媒介性疾患の治療法

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US (1) US20250002910A1 (https=)
EP (1) EP4346844A4 (https=)
JP (1) JP2024521792A (https=)
WO (1) WO2022251484A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11510939B1 (en) 2019-04-19 2022-11-29 Apellis Pharmaceuticals, Inc. RNAs for complement inhibition
WO2022226127A1 (en) * 2021-04-20 2022-10-27 Alexion Pharmaceuticals, Inc. Compositions and methods for inhibiting complement component 3 expression
CN120265773A (zh) * 2022-10-14 2025-07-04 美国圣因生物股份有限公司 靶向c3的小干扰rna及其用途
EP4600358A1 (en) * 2023-04-14 2025-08-13 Rigerna Therapeutics (Suzhou) Co., Ltd. Compound for inhibiting c3 gene expression, pharmaceutical composition and use thereof
AU2024312039A1 (en) * 2023-06-21 2026-01-22 Changzhou Hansoh Pharmaceutical Co., Ltd. Sirna, conjugate which contain sirna, pharmaceutical composition and uses thereof
CN117050998B (zh) * 2023-08-25 2024-02-09 青岛农业大学 一种miRNA在防治溴氰虫酰胺抗性烟粉虱中的应用
JPWO2025143000A1 (https=) * 2023-12-27 2025-07-03
WO2025168134A1 (zh) * 2024-02-08 2025-08-14 北京安龙生物医药有限公司 靶向补体成分c3基因的寡核苷酸及其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019113301A (ru) * 2016-10-17 2020-11-17 Апеллис Фармасьютикалс, Инк. Комбинированная терапия для ингибирования с3
AU2018360697A1 (en) * 2017-11-01 2020-05-14 Alnylam Pharmaceuticals, Inc. Complement component C3 iRNA compositions and methods of use thereof

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WO2022251484A9 (en) 2023-10-12
EP4346844A4 (en) 2025-09-10
EP4346844A1 (en) 2024-04-10
US20250002910A1 (en) 2025-01-02
WO2022251484A1 (en) 2022-12-01

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