JP2024521696A5 - - Google Patents

Info

Publication number
JP2024521696A5
JP2024521696A5 JP2023571764A JP2023571764A JP2024521696A5 JP 2024521696 A5 JP2024521696 A5 JP 2024521696A5 JP 2023571764 A JP2023571764 A JP 2023571764A JP 2023571764 A JP2023571764 A JP 2023571764A JP 2024521696 A5 JP2024521696 A5 JP 2024521696A5
Authority
JP
Japan
Prior art keywords
egfr
subject
seq
administered
bispecific anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2023571764A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024521696A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/054628 external-priority patent/WO2022243900A1/en
Publication of JP2024521696A publication Critical patent/JP2024521696A/ja
Publication of JP2024521696A5 publication Critical patent/JP2024521696A5/ja
Withdrawn legal-status Critical Current

Links

JP2023571764A 2021-05-18 2022-05-18 併用治療のためのがん患者を同定するための方法 Withdrawn JP2024521696A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163190004P 2021-05-18 2021-05-18
US63/190,004 2021-05-18
PCT/IB2022/054628 WO2022243900A1 (en) 2021-05-18 2022-05-18 Methods for identifying cancer patients for combination treatment

Publications (2)

Publication Number Publication Date
JP2024521696A JP2024521696A (ja) 2024-06-04
JP2024521696A5 true JP2024521696A5 (https=) 2025-05-19

Family

ID=81927585

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023571764A Withdrawn JP2024521696A (ja) 2021-05-18 2022-05-18 併用治療のためのがん患者を同定するための方法

Country Status (11)

Country Link
US (1) US20220372581A1 (https=)
EP (1) EP4341440A1 (https=)
JP (1) JP2024521696A (https=)
KR (1) KR20240007758A (https=)
CN (1) CN117716050A (https=)
AU (1) AU2022276181A1 (https=)
BR (1) BR112023024079A2 (https=)
CA (1) CA3220465A1 (https=)
MX (1) MX2023013784A (https=)
TW (1) TW202309094A (https=)
WO (1) WO2022243900A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021016149A2 (pt) 2019-02-26 2021-10-13 Janssen Biotech, Inc. Terapias de combinação e estratificação de pacientes com anticorpos biespecíficos anti-egfr/c-met
CN120131659B (zh) * 2025-05-09 2025-10-28 中国医学科学院基础医学研究所 Mobocertinib与抗PD-1抗体联合应用治疗癌症的方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0281604B1 (en) 1986-09-02 1993-03-31 Enzon Labs Inc. Single polypeptide chain binding molecules
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2156149T3 (es) 1992-12-04 2001-06-16 Medical Res Council Proteinas de union multivalente y multiespecificas, su fabricacion y su uso.
AUPO591797A0 (en) 1997-03-27 1997-04-24 Commonwealth Scientific And Industrial Research Organisation High avidity polyvalent and polyspecific reagents
EP3042964A1 (en) 2004-06-04 2016-07-13 Genentech, Inc. Egfr mutations
WO2006028936A2 (en) 2004-09-02 2006-03-16 Genentech, Inc. Heteromultimeric molecules
AU2006232287B2 (en) 2005-03-31 2011-10-06 Chugai Seiyaku Kabushiki Kaisha Methods for producing polypeptides by regulating polypeptide association
DE102005028778A1 (de) 2005-06-22 2006-12-28 SUNJÜT Deutschland GmbH Mehrlagige Folie mit einer Barriere- und einer antistatischen Lage
PT1999154E (pt) 2006-03-24 2013-01-24 Merck Patent Gmbh Domínios proteicos heterodiméricos modificados
JP2009541275A (ja) 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー/エス 二重特異性抗体の生産
KR20100058509A (ko) 2007-07-31 2010-06-03 메디뮨 엘엘씨 다중특이적 에피토프 결합 단백질 및 이의 용도
US20090162359A1 (en) 2007-12-21 2009-06-25 Christian Klein Bivalent, bispecific antibodies
US8227577B2 (en) 2007-12-21 2012-07-24 Hoffman-La Roche Inc. Bivalent, bispecific antibodies
US8242247B2 (en) 2007-12-21 2012-08-14 Hoffmann-La Roche Inc. Bivalent, bispecific antibodies
US9266967B2 (en) 2007-12-21 2016-02-23 Hoffmann-La Roche, Inc. Bivalent, bispecific antibodies
WO2010129304A2 (en) 2009-04-27 2010-11-11 Oncomed Pharmaceuticals, Inc. Method for making heteromultimeric molecules
HRP20241208T1 (hr) 2010-04-20 2024-11-22 Genmab A/S Heterodimerni proteini koji sadrže fc fragment protutijela i postupci za njihovu proizvodnju
MX2013002084A (es) * 2010-08-31 2013-05-09 Genentech Inc Biomarcadores y metodos de tratamiento.
ES2758994T3 (es) 2010-11-05 2020-05-07 Zymeworks Inc Diseño anticuerpo heterodimérico estable con mutaciones en el dominio Fc
BR112014010580B1 (pt) 2011-11-04 2021-01-12 Zymeworks, Inc. constructo de fc heteromultimérico isolado, composição, uso de um constructo de fc heteromultimérico isolado, composição de ácido nucléico e método para expressar o constructo de fc heteromultimérico isolado
MX361088B (es) 2012-11-21 2018-11-26 Janssen Biotech Inc Anticuerpos del receptor del factor de crecimiento epidérmico aislado/del receptor del factor de crecimiento de hepatocitos (egfr/c-met) biespecíficos.
EP2929350A4 (en) * 2012-12-04 2016-11-16 Caris Mpi Inc MOLECULAR PROFILING OF CANCER
JP2016515380A (ja) * 2013-03-15 2016-05-30 ライフ テクノロジーズ コーポレーション 肺癌の分類及び実施可能性インデックス
US20200157563A1 (en) * 2017-07-18 2020-05-21 The Broad Institute, Inc. Methods of producing human cancer cell models and methods of use

Similar Documents

Publication Publication Date Title
Dziadziuszko et al. Afatinib in NSCLC with HER2 mutations: results of the prospective, open-label phase II NICHE trial of European Thoracic Oncology Platform (ETOP)
Tan et al. Next-generation epidermal growth factor receptor tyrosine kinase inhibitors in epidermal growth factor receptor-mutant non-small cell lung cancer
CN110678483B (zh) 用抗pd-1抗体治疗肿瘤的方法
CN111032082B (zh) Her2阳性癌症的治疗
US20150231238A1 (en) Overcoming resistance to erbb pathway inhibitors
JP2022521610A5 (https=)
CN110325191A (zh) 以较少的副作用治疗egfr-驱动的癌症
US11845994B2 (en) Response to EGFR blockade
US8426418B2 (en) Method to treat melanoma in BRAF inhibitor-resistant subjects
TW201032796A (en) Treatment of lung cancer with a PARP inhibitor in combination with a growth factor inhibitor
CN112912403A (zh) 治疗肿瘤的方法
McPherson et al. A phase 2 trial of buparlisib in patients with platinum‐resistant metastatic urothelial carcinoma
JP2024521696A5 (https=)
US20190269666A1 (en) Combination therapy with merestinib and anti-pd-l1 or anti-pd-1 inhibitors for use in the treatment of cancer
CN103717616A (zh) 表皮生长因子受体基因中的突变
Kim et al. Pembrolizumab plus mFOLFOX7 or FOLFIRI for microsatellite stable/mismatch repair-proficient metastatic colorectal cancer: KEYNOTE-651 cohorts B and D
Spicer et al. A phase II study of neoadjuvant opnurasib KRAS G12C inhibitor in patients with surgically resectable non-small cell lung cancer (CCTG IND. 242A): A substudy of the IND. 242 platform master protocol
CN107949401A (zh) 联合施用酪氨酸激酶抑制剂来抑制表皮生长因子/表皮生长因子受体途径的方法及组合物
Kim et al. An open-label, phase IB/II study of abemaciclib with paclitaxel for tumors with CDK4/6 pathway genomic alterations
WO2023159066A1 (en) Use of niraparib for the treatment of brain cancer
CN117561062A (zh) 使用贝伐拉非尼和考比替尼或使用贝伐拉非尼、考比替尼和阿特珠单抗的组合疗法
TW202320790A (zh) 治療癌症之方法
RU2023132992A (ru) Способы выявления пациентов с онкологическими заболеваниями для комбинированного лечения
JP2023523450A5 (https=)
US20260116962A1 (en) Plk1 inhibitor in combination with anti-angiogenics for treating metastatic cancer