JP2024520987A5 - - Google Patents

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Publication number
JP2024520987A5
JP2024520987A5 JP2023560188A JP2023560188A JP2024520987A5 JP 2024520987 A5 JP2024520987 A5 JP 2024520987A5 JP 2023560188 A JP2023560188 A JP 2023560188A JP 2023560188 A JP2023560188 A JP 2023560188A JP 2024520987 A5 JP2024520987 A5 JP 2024520987A5
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JP
Japan
Prior art keywords
probe
fragment
amplifier
tertiary
primary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023560188A
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English (en)
Japanese (ja)
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JP2024520987A (ja
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Application filed filed Critical
Priority claimed from PCT/US2022/021826 external-priority patent/WO2022250774A1/en
Publication of JP2024520987A publication Critical patent/JP2024520987A/ja
Publication of JP2024520987A5 publication Critical patent/JP2024520987A5/ja
Pending legal-status Critical Current

Links

JP2023560188A 2021-05-24 2022-03-24 指数関数的な放射輝度と結びつく連鎖増幅 Pending JP2024520987A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163192554P 2021-05-24 2021-05-24
US63/192,554 2021-05-24
PCT/US2022/021826 WO2022250774A1 (en) 2021-05-24 2022-03-24 Linked amplification tethered with exponential radiance

Publications (2)

Publication Number Publication Date
JP2024520987A JP2024520987A (ja) 2024-05-28
JP2024520987A5 true JP2024520987A5 (https=) 2025-04-01

Family

ID=81308076

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023560188A Pending JP2024520987A (ja) 2021-05-24 2022-03-24 指数関数的な放射輝度と結びつく連鎖増幅

Country Status (7)

Country Link
US (1) US20240240237A1 (https=)
EP (1) EP4347874A1 (https=)
JP (1) JP2024520987A (https=)
KR (1) KR20240013728A (https=)
CN (1) CN117460837A (https=)
CA (1) CA3213718A1 (https=)
WO (1) WO2022250774A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025007154A1 (en) * 2023-06-30 2025-01-02 California Institute Of Technology Signal amplification methods and compositions for molecular target detection by iterative probe deposition
WO2025194315A1 (zh) * 2024-03-18 2025-09-25 深圳华大智造科技股份有限公司 核酸检测方法及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681697A (en) * 1993-12-08 1997-10-28 Chiron Corporation Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
US8481268B2 (en) * 1999-05-21 2013-07-09 Illumina, Inc. Use of microfluidic systems in the detection of target analytes using microsphere arrays
WO2011038403A1 (en) * 2009-09-28 2011-03-31 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
US20120004132A1 (en) * 2010-07-02 2012-01-05 Affymetrix, Inc. Detection of Nucleic Acids and Proteins
US8658361B2 (en) * 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
CN103649331A (zh) * 2011-02-15 2014-03-19 莱卡生物系统纽卡斯尔有限责任公司 用于mrna的定位的原位检测的方法
CN116200462B (zh) * 2016-05-16 2025-10-03 布鲁克空间生物学公司 用于检测样品中目标核酸的方法
EP4556575A3 (en) * 2016-11-21 2025-10-08 Bruker Spatial Biology, Inc. A method for sequencing nucleic acids
CN118345145A (zh) * 2016-12-09 2024-07-16 乌尔蒂维尤股份有限公司 用于使用标记的核酸成像剂进行多路复用成像的改进方法
EP4063519B1 (en) * 2018-04-09 2023-09-13 Advanced Cell Diagnostics, Inc. Methods to further enhance signal amplification for the in situ detection of nucleic acids
EP3894583A4 (en) * 2018-12-13 2022-11-09 President and Fellows of Harvard College AMPLIFICATION METHODS AND SYSTEMS FOR MERFISH AND OTHER APPLICATIONS

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